Clinical trials: Normal Skin
Atopic Dermatitis, Pediatric ALL
TRacking Atopic Dermatitis Infants and Their Microbiome (TRAM)
TRacking Atopic dermatitis Infants and their Microbiome: A study to primarily assess the user experience of parents of infants with early onset eczema and parents of healthy infants on OneBiome real-world evidence research…
- Trial name
- TRAM (NCT06578351)
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Glucose Intolerance
Dorzagliatin and 1st Phase Insulin and Beta-cell Glucose Sensitivity in IGT and NGT
Dorzagliatin, a novel dual allosteric activator of glucokinase. reduces blood glucose by increasing insulin secretion by enhancing sensitivity of beta cells to glucose.
- Trial name
- NCT05468229
- Testing
- Dorzagliatin
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Androgenetic Alopecia
Split Wound Comparison of Trichophytic Closure Techniques for Donor Site in Hair Transplantation
This study aim to compare cosmetic results between 3 trichophytic closure techniques for donor site (the trimming of upper, lower and both edge of linear incision) in hair transplantation.
- Trial name
- NCT01655602
- Testing
- Trichophytic closure upper edge trimming, Trichophytic closure lower edge trimming, Trichophytic closure both edge trimming
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Breast Cancer, Invasive Breast Carcinoma
Tissue- and Serum-Derived Exosomal microRNAs as Predictors of Neoadjuvant Chemotherapy Response in Breast Cancer
This prospective observational study aims to evaluate whether exosomal microRNA profiles derived from tumor tissue and blood serum are associated with pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in…
- Conditions
- Breast Cancer, Invasive Breast Carcinoma, Exosomal microRNA, Neoadjuvant Chemotherapy Response
- Trial name
- ExoTSS-BC (NCT07500129)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlas University
Healthy
Distinction of Cone Outer Segment Tips by Spectral-Domain Optical Coherence Tomography in Normal Eyes
The aim of this study is to investigate the incidence and possible causes of obscured or disrupted cone outer segment tips line at fovea in spectral-domain optical coherence tomography images of normal eyes.
- Trial name
- NCT01316003
- Testing
- Optical coherence tomography
- Where
- Japan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Kyorin University
Breast Neoplasms
Prevention of Female Cancers by Optimization of Selenium Levels in the Organism.
Hypothesis to be tested: Oral supplementation or diet modifications of selenium to a specified range will be effective in reducing the risk of developing cancer of any type in women with high risk of breast cancer, as compared to…
- Trial name
- SELINA (NCT04014283)
- Testing
- Diet modification
- Where
- Poland
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Read-Gene S.A.
Breast Cancer
Decision-aid on Breast Cancer Screening
The present study aim to assess the effect of an interactive web decision aid on informed choice - measured via knowledge, attitudes and intentions concerning breast cancer screening - comparing the decision aid with a standard…
- Trial name
- NCT03097653
- Testing
- Decision-aid, Standard information
- Where
- 7 sites in Italy
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Melanoma
Melanoma Perception and Health Literacy in People of Color
This study will examine the effectiveness of a targeted, health literate educational intervention for people of color compared to a standard melanoma education pamphlet for increasing knowledge and promoting early melanoma…
- Trial name
- NCT02437305
- Testing
- ABCDEs of Melanoma Skin Cancer, ABCDEs of Melanoma
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Breast Cancer, Weight Loss
Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk
The primary specific aim of this study was to determine if overweight and obese premenopausal women can lose weight and if long term weight loss impacts biomarkers associated with breast cancer risk.
- Trial name
- LEAF (NCT01559194)
- Testing
- Low Fat Diet plus exercise, Low Carbohydrate diet + Exercise
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Diabetic Foot, Health Behavior
Manipulating Narrative Presentations of Information to Encourage Good Foot Care Practice in People With and Without Diabetes Mellitus
The study explores the role of health messages (narrative, non-narrative vs. control condition [no message]) to enhance good foot care practices among people with diabetes and the general population.
- Conditions
- Diabetic Foot, Health Behavior, Foot Diseases
- Trial name
- NCT04623151
- Testing
- Online leaflet about foot care
- Where
- United Kingdom
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Chichester
Healthy, Type 1 Diabetes
Subcutaneous Administration of Lisofylline to Healthy Normal Subjects and Subjects With Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is an autoimmune disease. Autoimmune diseases happen when the immune system does not identify part of the body as belonging to it.
- Trial name
- NCT00896077
- Testing
- Lisofylline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DiaKine Therapeutics, Inc.
Breast Cancer
Evaluation of Real Imaging's 3D Functional Metabolic Imaging and Risk Assessment (MIRA) System
Three-dimensional functional Metabolic Imaging (3D MIRA) is a new infrared imaging technology using the Real Imager 8 (RI8) developed by Real Imaging.
- Trial name
- NCT02155075
- Testing
- MIRA device imaging
- Where
- Israel
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Real Imaging Ltd.
Increased Risk for Development of Breast Cancer
Pilot Study of Bazedoxifene Plus Conjugated Estrogen on Imaging and Blood Biomarkers
Pilot study to test feasibility of 6 months of bazedoxifene (BZA) plus conjugated estrogens (CE) to modulate breast MRI parameters.
- Trial name
- NCT04821375
- Testing
- bazedoxifene plus conjugated estrogens
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Rheumatoid Arthritis, Spondylitis, Ankylosing
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases
Introduction: Patients with autoimmune rheumatic diseases (ARDs), rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PAs), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), primary…
- Conditions
- Rheumatoid Arthritis, Spondylitis, Ankylosing, Spondyloarthritis, Systemic Lupus Erythematosus
- Trial name
- RZVRheum (NCT05879419)
- Testing
- Recombinant Herpes Zoster Vaccine (RZV), MTX Discontinuation, MMF Discontinuation
- Where
- Brazil
- Volunteers
- 2,005 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Psoriasis Vulgaris
Comparison of Refined and Crude Indigo Naturalis Ointment in Treating Psoriasis
To compare the efficacy and safety of refined indigo naturalis ointment with that of crude ointment in treating psoriasis.
- Trial name
- NCT01022502
- Testing
- refined indigo naturalis ointment, crude indigo naturalis ointment
- Where
- Taiwan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yin-ku Lin
Renal Impairment
Phase 1 Study of PK and Safety of HM15912 (Sonefpeglutide) in Subjects With Normal and Severe Kidney Function
An Open-label, Single-dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HM15912 in Subjects with Renal Impairment and Matched Control Subjects with Normal Renal Function
- Trial name
- NCT05711381
- Testing
- HM15912
- Where
- 4 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Melasma
Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy
This research is a clinical study with a single-blind randomized clinical trial design (randomized controlled trial) in RSCM-FKUI This study aims to Assess the effectiveness and safety of intradermal concentrated secretome…
- Trial name
- NCT06516419
- Testing
- Concentrated secretome Injection 2mL, Tranexamic acid injection, Triple Combination Cream
- Where
- 2 sites in Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Dyspepsia
Gastric Motor Function Measurement in Dyspepsia and Normal Subjects
This study is being done to measure the functions of the stomach after eating a meal and to develop a new method that will simultaneously measure both gastric emptying and the relaxation of the stomach after a meal using nuclear…
- Trial name
- NCT00296582
- Testing
- Gastric Motor Function Measurement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Normal Glucose Metabolism
Assessment of Non-Fasting vs. Fasting Lipid Measures in Diabetes Patients
This study will examine whether fasting and non-fasting lipid measures can provide similar clinical information in order to guide lipid management by primary physicians. It will compare fasting vs.
- Conditions
- Diabetes Mellitus, Normal Glucose Metabolism, Hyperlipidemia
- Trial name
- NCT00569959
- Testing
- fasting 12+ hours, Non-fasting
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Cutaneous Leishmaniasis
Safety and Efficacy of Low-Dose Pentavalent Antimony for Treatment of Cutaneous Leishmaniasis
The purpose of this study is to determine whether low-dose pentavalent antimony is equally effective when compared to the standard-dose regimen in patients with cutaneous leishmaniasis.
- Trial name
- Lowdosesb (NCT00317980)
- Testing
- Meglumine antimoniate
- Where
- Brazil
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
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