Clinical trials: Normal Skin
Atopic Disease
Microbiome and Atopy in Mali
This study is about allergic diseases in people living in Mali. Allergic diseases can cause health problems like asthma or skin rashes.
- Trial name
- NCT07051902
- Where
- 2 sites in Mali
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Skin Cancer
Chemical Peels and Fractional Laser on IGF-1 Levels in Skin
The purpose of this study is to evaluate the impact of fractional laser versus chemical peels on IGF-1 levels in skin.
- Trial name
- NCT03775031
- Testing
- Fractional Laser and Chemical Peel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Normal Healthy Volunteers
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Minocin (Minocycline) for Injection in Healthy Adults
This was a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose study of the safety, tolerability, and pharmacokinetics of Minocin (minocycline) for injection in healthy adult participants.
- Trial name
- NCT02802631
- Testing
- Minocin (minocycline) for Injection
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.)
Systemic Sclerosis (SSc), Sexual Dysfunctions
Relationship Between Pelvic Floor Dysfunctions and Sexual Dysfunction in Female Patients with Systemic Sclerosis
Relationship Between Pelvic Floor Dysfunctions and Sexual Dysfunction in Female Patients with Systemic Sclerosis
- Conditions
- Systemic Sclerosis (SSc), Sexual Dysfunctions, Pelvic Floor Disorder
- Trial name
- NCT06769399
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Normal Healthy
Single Dose, Repeated Dose, and Conditional Food Effect Study of PF-05221304 in Healthy Subjects
The current study is the first clinical trial proposed with PF-05221304. It is designed to evaluate the safety, tolerability, and pharmacokinetics (PK) following administration of single and repeated doses of PF-05221304 to…
- Trial name
- NCT02871037
- Testing
- PF-05221304
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Pfizer
Recurrent/Metastatic Breast Cancer
Clinical Trial for Effect of TQB3616 Capsule on Pharmacokinetics in Healthy Adult Subjects
TQB3616 capsule is a small molecule oral drug developed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd., which inhibits cyclin-dependent kinases 4 and 6 (CDK4/6).
- Trial name
- NCT05344729
- Testing
- TQB3616 Capsule
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Acne
Study Evaluating the Efficacy and Safety of TheraClearX on Mitigating Mild to Moderate Acne
The goal of this clinical trial is to further substantiate the effectiveness and safety of TheraClearX as a stand-alone treatment of mild to moderate acne in healthy teenagers and adults ages 12-40 over the course of 7 weeks.
- Trial name
- NCT06043102
- Testing
- TheraClearX
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ablon Skin Institute Research Center
Skin and Subcutaneous Tissue Fungal Infections
Superficial and Cutaneous Fungal Infections Among Drug-users in Northeast Region of Iran
The purpose of this study was about survey of prevalence of fungal infections among drug users referring to methadone wards of Hospitals in northeast region of Iran
- Trial name
- NCT02681458
- Testing
- Direct Examination
- Where
- Iran
- Volunteers
- 1,436 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University of Mashhad
Stretch Marks
Effect of Radiofrecuency on Stretch Marks
This study aims to explore the effects of fractional Radiofrecuency (RF), as well as demonstrate the performance of the new semi-ablative radiofrequency model in the treatment of stretch marks.
- Trial name
- FRF (NCT03931525)
- Testing
- Fractitional Radiofrecuency with Drug Delivery, Fractitional Radiofrecuency
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Quiropraxia y Equilibrio
Acne Rosacea
A Pilot Study on the Use of Seysara for Rosacea
This is a prospective, parallel group, randomized, investigator-blinded pilot study. Approximately 100 subjects will be randomized at a 3:1 ratio to Seysara (sarecycline) at a weight-based dose per label or Centrum Adult…
- Trial name
- NCT04555525
- Testing
- sarecycline, Centrum Adult Multivitamin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Infection, Soft Tissue, Infection, Wound
Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion
This study focuses on a new drug delivery system (Direct Antibiotic Delivery) to treat soft tissue infections. In this study, cefazolin is delivered directly to the target tissues using subcutaneous injection of antibiotic…
- Conditions
- Infection, Soft Tissue, Infection, Wound, Cellulitis, Diabetic Foot Ulcer
- Trial name
- DAD (NCT01238276)
- Testing
- Cefazolin, Silberg Tissue Preparation System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sonescence, Inc.
Pleural Infection
Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic
Parapneumonic effusions caused by an infection of the pleural membranes occur in 40-57% of cases of pneumonia. A variable percentage (10-20%) of parapneumonic effusions progresses to empyema (pus) and/or abscess formation…
- Trial name
- PENTAD-FT (NCT05903417)
- Testing
- Intrapleural fibrinolytic with alteplase 5mg and pulmozyme 5 mg, Saline irrigation with 250 mls normal saline (over 1 hour)
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Kawasaki Disease
Multi-center Prospective Randomized Control Trail of High Dose Aspirin in Acute Stage of Kawasaki Disease
Kawasaki disease (KD) is an acute multi-system vasculitis syndrome of unknown etiology occurring mostly in infants and children younger than 5 years of age.
- Trial name
- NCT02359643
- Testing
- Aspirin
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Rheumatoid Arthritis
Alloimmune Response to Citrullinated Shared Epitope Sequence in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune and sistemic disease,characterized by joint sinovitis and the production of autoantibodies (Ab).
- Trial name
- ABSEC (NCT03506035)
- Testing
- Research new biomarker for RA
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Breast Cancer
Assessment of Feasibility and Acceptability of Personalized Breast Cancer Screening
The overall objective is to assess the acceptability and feasibility of offering personalized breast cancer (BC) screening. The specific objectives are: 1) To design an information system; 2) To evaluate the barriers and…
- Trial name
- DECIDO (NCT03791008)
- Testing
- Risk based screening
- Where
- Spain
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Venous Thromboses, Venous Stasis
Evaluation of the OsciPulse Rapid Cycling Compression Device Effects on Venous Blood Flow
This study will evaluate the effects on venous blood flow of the investigational device, OsciPulse system, which is an external intermittent limb compression device.
- Trial name
- NCT05087108
- Testing
- OsciPulse system, Reference Therapy 1, Refence Therapy 2
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- OsciFlex LLC
Bioavailability of ASP015K, Pharmacokinetics of ASP015K
A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K
The purpose of this study is to determine the relative bioavailability and pharmacokinetic profiles from three strengths of a new tablet formulation of ASP015K and to evaluate the safety and tolerability after a single dose of…
- Conditions
- Bioavailability of ASP015K, Pharmacokinetics of ASP015K, Healthy Subjects
- Trial name
- NCT01486017
- Testing
- ASP015K
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Breast Neoplasms
FATLAS: Comprehensive Multi-level Characterization of Systemic and Mammary Adiposity in Breast Cancer Patients.
FATLAS is a prospective, interventional, non Investigational Medicinal Product (IMP) study aiming to characterize the micro- and macroenvironment of breast cancer according to patient adiposity in different histological and…
- Trial name
- FATLAS (NCT04200768)
- Testing
- Prospective data and sample collection
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy
Validation of an Assay to Measure Cyclooxygenase-1 Activity
The purpose of this study is to obtain a reference range for a newly developed assay of ex vivo platelet COX-1 activity in normal volunteers taking a routine clinical dose of aspirin.
- Trial name
- NCT00761891
- Testing
- Chewable aspirin
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
IUGR, Pregnancy
Transplacental Gradients and Transport in Intrauterine Growth Restricted (IUGR) Pregnancies Compared to Normal Pregnancies.
The purpose of this study is to determine whether the transplacental gradients for 6 polyols and mannose are altered in intrauterine growth restricted (IUGR) pregnancies compared to normal pregnancies and b) to determine the…
- Trial name
- NCT02397291
- Testing
- Mannose, Myoinositol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
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