Clinical trials: Normal Skin
Schizophrenia
Comparison of Video Consent Versus Routine Consent for Participation in Research Studies
The purpose of this study is to examine a novel technique for improving the informed consent process for participation in research by the older psychiatric population.
- Trial name
- NCT00430391
- Testing
- DVD Consent, Routine Control
- Where
- United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Skin Aging, Sagging Skin
Facial Contouring With Monopolar RF and Continuous Water Cooling
The goal of this clinical trial is to assess whether a single RF-CWC (radiofrequency - continous water cooling) session can produce significant improvements in jawline contour and facial volume in women aged 38-50 years over 8…
- Conditions
- Skin Aging, Sagging Skin, Laxity; Skin
- Trial name
- NCT07317089
- Testing
- RF-CWC
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Contact Dermatitis
Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis
Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM.
- Trial name
- NCT06331390
- Testing
- niacinamide cosmetic product
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Facial Aging, Skin Laxity
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
The goal of this observational study is to evaluate the effectiveness and safety of microwave-assisted heating technology in facial fat reduction and skin tightening in Asians. The main questions it aims to answer are: 1.
- Conditions
- Facial Aging, Skin Laxity, Cheek Wrinkles
- Trial name
- NCT06925074
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chang Chang Cheng
DFU, VLU
BIO-SEE: Bioburden Imaging Outcome Study for Equivalence Evaluation
The study aims to demonstrate the substantial equivalence of the cureVision cV system's performance in detecting moderate to high bacterial loads in direct comparison to the comparator device for fluorescence imaging in wounds…
- Conditions
- DFU, VLU, Surgical Wound, Wounds
- Trial name
- NCT07611318
- Testing
- cureVision cV
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Capsicure, LLC
Orthopoxviral Disease, Smallpox
Phase I Trial of an Investigational Small Pox Medication
The purpose of this study was to evaluate the pharmacokinetic parameters and safety of a single dose of ST-246 400mg Form I versus ST-246 400mg Form V capsules in fed normal healthy volunteers.
- Conditions
- Orthopoxviral Disease, Smallpox, Monkey Pox
- Trial name
- NCT00728689
- Testing
- ST-246 Days 1 - 3, ST-246 Days 11 - 13
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- SIGA Technologies
Endotoxemia, Inflammation
In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia
Excessive inflammation is associated with tissue damage caused by over-activation of the innate immune system. This can range from mild disease to extreme conditions such as multiple organ failure (MOF).
- Conditions
- Endotoxemia, Inflammation, Multi Organ Dysfunction Syndrome
- Trial name
- VECTOR (NCT00785018)
- Testing
- C1-esterase inhibitor, Endotoxin administration
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Rheumatoid Arthritis, Healthy Volunteers
Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects.
The purpose of this study is to investigate the drug interaction between fostamatinib and rifampicin by comparing the safety, tolerability and plasma concentration of fostamatinib when administered alone and with rifampicin in…
- Trial name
- NCT01336218
- Testing
- fostamatinib, rifampicin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pregnancy, Systemic Lupus Erythematosus
Duke Autoimmunity in Pregnancy Registry
It is difficult to predict how a women with an autoimmune disease will do during pregnancy. Some women will improve, others will worsen. Some pregnancies progress normally and others become very complicated.
- Conditions
- Pregnancy, Systemic Lupus Erythematosus, Cutaneous Lupus, Rheumatoid Arthritis
- Trial name
- DAP Registry (NCT00513591)
- Where
- United States
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Duke University
Diet Interventions
The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)
The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.
- Trial name
- TASTY (NCT06758817)
- Testing
- MedDiet+ intervention, General dietary recommendations
- Where
- 2 sites in Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Breast Cancer
Increasing African Immigrant Women's Participation in Breast Cancer Screening
New York City (NYC) is home to a large and diverse immigrant population. Many of these groups face significant barriers to preventive health care, including lack of insurance, poor health care access and language difficulties.
- Trial name
- AIBCS (NCT04450264)
- Testing
- African Immigrant Breast Cancer Education Program
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetic Foot Ulcer, Type 2 Diabetes
Development of a Cellular Biomarker for the Diagnosis and Treatment of Diabetic Foot Ulcers
This project aims to result in the identification of such markers, and the development of a feasible quantitative method of distinguishing between tissue that has the capacity to heal and tissue that does not, thus identifying a…
- Trial name
- NCT02329366
- Testing
- Specimen Collection
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Rheumatoid Arthritis
Investigation of Muscle Oxygenation in Patients With Rheumatoid Arthritis
The aim of this study is to investigate respiratory muscle strength, respiratory muscle endurance, muscle oxygenation, upper extremity and lower extremity exercise capacity in rheumatoid arthritis patients compared with healthy…
- Trial name
- NCT06769386
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Rheumatoid Arthritis, Healthy Volunteers
Effects of Administration of Fostamatinib on Blood Concentrations of Pioglitazone in Healthy Subjects
The purpose of this study is to investigate the drug interaction between fostamatinib and pioglitazone by comparing the safety, tolerability and plasma concentration of pioglitazone when administered alone and with fostamatinib…
- Conditions
- Rheumatoid Arthritis, Healthy Volunteers, Pharmacokinetics, Pioglitazone
- Trial name
- NCT01309854
- Testing
- fostamatinib, pioglitazone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Diaper Rash
Clinical Study to Evaluate the Efficacy and Safety of Two Marketed Investigational Products in Children With Diaper Rash
To evaluate whether Desitin; Zinc Oxide Diaper Rash Ointment (Desitin Original) and Desitin Creamy; Zinc Oxide Diaper Rash Ointment (Desitin Creamy) provide relief of the signs and symptoms associated with diaper rash after 12…
- Trial name
- NCT00219466
- Testing
- Zinc Oxide Diaper Rash Ointment, Aloe Vera/Tocopherol/Zinc Oxide Cream
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Acne Vulgaris
Polymorphism of Extrapituitary Promoter of PRL Gene and Relationships With Serum Prolactin Levels in Acne Vulgaris.
Acne vulgaris is one of the most common skin diseases. It is a disease of the pilosebaceous units, clinically characterized by seborrhea, comedones, papules, pustules, nodules and, in some cases, scarring.
- Trial name
- NCT03186222
- Testing
- blood sample
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Skin Hyperpigmentation, Dry Skin; Eczema
Efficacy and Safety Assessment of Niacinamide Cosmetic Preparation: a Randomized Controlled Trial
Niacinamide in lower concentrations has been recognized as a cosmetic ingredient with hydrating properties. Therefore, aim was to test the efficacy and safety of niacinamide cosmetic preparation in A Randomized, Controlled Trial.
- Trial name
- NCT06189105
- Testing
- miss alice face it you love me serum, No treatment (usual skincare rutine)
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Mammogram Uptake, Breast Cancer
Trial to Evaluate the Impact of Various Pragmatic Interventions to Increase Mammography Uptake Among Defaulted Repeat Screeners in Singapore
Breast cancer is the most common cancer among women in Singapore, accounting for nearly 30% of all female cancers. While regular biennial mammography can reduce mortality, screening rates in Singapore remain low at 34.7%; well…
- Conditions
- Mammogram Uptake, Breast Cancer, Breast Neoplasm, Early Detection of Cancer
- Trial name
- REMIND1 (NCT07651345)
- Testing
- Arm 2: One mailed reminder, Arm 3: Two mailed reminders, Arm 4: Mailed reminder with prescheduled appointment
- Where
- Singapore
- Volunteers
- 12,750 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Psoriasis
Efficacy of Two Algae Formulations on Lipid Metabolism, Inflammation and Oxidative Stress Status in Individuals With Psoriasis
Our overall goal is to evaluate the safety and efficacy of consumption of two algae formulations compared to a placebo on: degree of severity of skin lesions, plasma lipid levels, as well as other health-related markers, in…
- Trial name
- PCA (NCT01045395)
- Testing
- Corn starch, Unique Marine Algae Concentrate (UMAC), Golden brown algae
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Labour Analgesia
Spinal Analgesia in Labour Pain
To evaluate the efficacy and safety of dexmedetomidine as an adjuvant to bupivacain and fentanyl in spinal Analgesia to decreases pain during normal labour
- Trial name
- NCT07332130
- Testing
- injecting dexmedetomidine, injecting mixture of bupivacaine fentanyl
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minia University Hospital
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