Clinical trials: Normal Skin
Hidradenitis Suppurativa
A Proof-of-Concept Study of LAD328 in Adults With Hidradenitis Suppurativa
The main purpose of this study is to evaluate the effect of LAD328 compared to placebo in participants with moderate-to-severe Hidradenitis Suppurativa (HS), and to access the safety, tolerability, pharmacokinetic and…
- Trial name
- NCT07547813
- Testing
- LAD328
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Almirall, S.A.
Lipodystrophy
Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management
This study aims to compare the hemodynamic parameters, postoperative plethysmography variability index, the total amount of postoperative intravenous fluid administration needed, and the urine output of two methods of fluid…
- Trial name
- NCT05930106
- Testing
- Intraoperative fluid ratio, Carotid Artery Doppler Peak Velocity Variation
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TJ Plast Advanced Center for Plastic Surgery
Breast Cancer
Gemcitabine Hydrochloride and Genistein in Treating Women With Stage IV Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as gemcitabine hydrochloride and genistein, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00244933
- Testing
- genistein, gemcitabine, Tumor biopsy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Solid Tumor
Neo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03)
The primary objective of this study is to evaluate the safety of Neo-T in combination with anti-PD1 in patients with solid tumors.
- Trial name
- NCT05798533
- Testing
- Neo-T, Toripalimab, Tislelizumab
- Where
- 2 sites in China
- Volunteers
- 6 people
- Sponsor
- BGI, China
Breast Cancer
Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy
The objective of the proposed research is to develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) for the diagnosis of breast cancer and test its performance as an…
- Trial name
- NCT00734838
- Testing
- High Resolution Microendoscope
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Duke University
HER 2 Positive Advanced Breast Cancer, Breast Cancer
Phase Ib/II Study of Zanidatamab Plus Tucatinib and Chemotherapy in HER2-Positive Advanced Breast Cancer
The JAZMINE study is a multicenter, open-label, non-comparative, phase Ib/II clinical trial to evaluate safety and preliminary efficacy of zanidatamab in combination with tucatinib and chemotherapy (capecitabine or eribulin…
- Trial name
- JAZMINE (NCT07494448)
- Testing
- Zanidatamab, Tucatinib, Capecitabine
- Volunteers
- 24 people
- Sponsor
- MedSIR
Breast Cancer
Individuals on Hormone Therapy Breast Cancer Screening Pilot
This investigation is a prospective breast cancer screening study open to all individuals on hormone therapy. Using a mixed methods approach, the study will 1) gather prospective quantitative breast imaging data in conjunction…
- Trial name
- NCT06383026
- Testing
- Breast Cancer Screening, Survey/Interview, Focus Group
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Aromatase Inhibitor-Associated Musculoskeletal Syndrome, Arthralgia Syndrome
AKU Study - Acupuncture for Aromatase Inhibitor-Induced Musculoskeletal Syndrome
Third-generation aromatase inhibitors (AIs) represent a standard adjuvant endocrine treatment for postmenopausal and high-risk premenopausal women with hormone receptor-positive early breast cancer.
- Conditions
- Aromatase Inhibitor-Associated Musculoskeletal Syndrome, Arthralgia Syndrome, Early Breast Cancer (EBC)
- Trial name
- AKU (NCT07909785)
- Testing
- Manual Acupuncture
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Masaryk Memorial Cancer Institute
Rheumatoid Arthritis
Predictive Analytics for Theranosis in RA
RA is the most common inflammatory, persistent and progressive disease of the joints with serious co-morbidities and huge health and socio-economic impact worldwide.
- Trial name
- PAnTheRA (NCT02928276)
- Testing
- RheumaKit: Prediction of the response to anti-TNFs DMARDs
- Where
- 5 sites in Belgium, Spain
- Volunteers
- 110 people
- Sponsor
- DNAlytics
Psoriasis
A Comparison Between Clobetasol Propionate 0.05% (Clobex®) Spray and Clobetasol Propionate 0.05% (Olux®) Foam
The primary objective of this study is to evaluate the efficacy and safety of clobetasol propionate 0.05% (Clobex®) spray compared to clobetasol propionate 0.05% (Olux®) foam.
- Trial name
- NCT00436540
- Testing
- Clobetasol Propionate 0.05% Spray, Clobetasol Propionate 0.05% Foam
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Galderma R&D
Osteoporosis, Breast Cancer
Effect Of Whole Body Vibration Versus Weight Bearing Exercises On Osteoporosis In Breast Cancer Patients After Chemotherapy
Chemotherapy can damage bone marrow and therefore impair the production of white blood cells, platelets and red blood cells with the resulting anemia and osteoporosis.
- Trial name
- NCT05970250
- Testing
- Whole body vibration group, Weight bearing exercises, vitamin D supplements and calcium
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Foot Ulcer, Diabetes Mellitus
The Prevalence of Foot Complaints/Problems and Ulcers in a Pre-dialysis Population
Diabetes mellitus is one of the main causes of chronic kidney disease (CKD) and an increased risk of foot complications is seen in patients suffering from both DM and CKD.
- Conditions
- Foot Ulcer, Diabetes Mellitus, Chronic Kidney Diseases, Pre-dialysis
- Trial name
- NCT04784650
- Testing
- Pre-dialysis population
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Malignant Neoplasm in the Brain
Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases
This phase II trial studies how well stereotactic radiosurgery works in treating patients with melanoma that has spread to more than 3 places in the brain.
- Conditions
- Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Pathologic Stage IV Cutaneous Melanoma AJCC v8
- Trial name
- NCT01644591
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- M.D. Anderson Cancer Center
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
This research trial is testing a combination of two experimental drugs, MSC1936369B (Mitogen-activated protein extracellular signal-regulated kinase (MEK) Inhibitor) and SAR245409 (Phosphatidylinositol 3-kinase (Pi3K)/Mammalian…
- Conditions
- Locally Advanced Solid Tumor, Metastatic Solid Tumor, Breast Cancer, Non Small Cell Lung Cancer
- Trial name
- NCT01390818
- Testing
- MSC1936369B (pimasertib), SAR245409 (PI3K and mTOR inhibitor)
- Where
- 8 sites in United States, Italy and 1 more
- Volunteers
- 146 people
- Sponsor
- EMD Serono
Breast Cancer, Uterine Cancer
Musicotherapy in the Reduction of Fatigue in Women With Breast or Gynecological Cancer Under Radiotherapy
OBJETIVE: To study the influence of musicotherapy in reduction of fatigue related to cancer in patients with breast's or gynecology's cancer, during the radiotherapy treatment.
- Conditions
- Breast Cancer, Uterine Cancer, Ovarian Cancer
- Trial name
- NCT01570218
- Testing
- Music therapy
- Where
- 2 sites in Brazil
- Volunteers
- 164 people
- Sponsor
- Universidade Federal de Goias
Breast Cancer, Age
The Association Between Age-related Peripheral Blood Components and Treatment Efficacy in Breast Cancer
This study is a single-center, prospective/retrospective, observational clinical research designed to compare the differences in peripheral blood components between young and elderly HR+HER2- breast cancer patients, and to…
- Trial name
- NCT06718010
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fudan University
Breast Cancer
Eradication of Malignant Carcinoma in the Breast Tissue
The purpose of this study is to confirm the findings of an early study and expand our knowledge of treating Malignant Carcinoma in the Breast Tissue Using an ATP (Adenosine-5'-Triphosphate) Inhibitor.
- Trial name
- NCT02286778
- Testing
- Acetogenins
- Volunteers
- 60 people
- Sponsor
- Optimal Health Research
Breast Cancer
Breast Cancer Surveillance Consortium
The Breast Cancer Surveillance Consortium (BCSC) database contains data from 1994-2009 on breast cancer screening, quality, and outcomes, and its main goal is to advance breast cancer research.
- Trial name
- BCSC (NCT01831778)
- Where
- United States
- Volunteers
- 2,345,817 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Ovarian Response
Androgens for Poor Responders in In Vitro Fertilization
it has been shown that androgens in non human primates may favour follicular growth in the ovaries when animals are treated with gonadotropins which are the hormones used in patients receiving treatment with in vitro…
- Trial name
- NCT00693108
- Testing
- Transdermal testosterone
- Where
- Spain
- Sponsor
- Hospital Clinic of Barcelona
Breast Cancer
Brain Mets - Capecitabine Plus Sunitinib and WBRT
The purpose of this study is to assess the efficacy and safety of concurrent whole brain radiotherapy (WBRT) and capecitabine followed by combination capecitabine and sunitinib in treating patients with CNS metastases from breast…
- Trial name
- NCT00570908
- Testing
- sunitinib, capecitabine, WBRT
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Baylor Breast Care Center
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