Clinical trials: Normal Skin
Breast Cancer
Local Treatment by Thermic Destruction of Primitive Breast Cancer
Demonstrate the effectiveness of laser in the treatment of cancerous lesions by determinating with histological analysis of the specimen the percentage of tumor cells remaining in the area treated by the laser
- Trial name
- LASERBREAST1 (NCT01706016)
- Testing
- Thermic destruction of tissue by Laser using the Novilase device
- Where
- 3 sites in France
- Volunteers
- 16 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Ovarian Neoplasms, Colorectal Neoplasms
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy.
- Conditions
- Ovarian Neoplasms, Colorectal Neoplasms, Melanoma, Small Cell Lung Cancer
- Trial name
- NCT00132704
- Testing
- Ionizing radiation (IR) therapy, Ionizing radiation (IR)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Skin Inflammation
Broccoli Seed Extract and Skin Health
The primary objective of this study is to examine the influence of 4-weeks ingestion of TrueBroc®, (broccoli seed extract, BSE) with mustard seed powder (MSP) on improving skin health by evaluating skin physiological and…
- Trial name
- NCT05745636
- Testing
- Broccoli, mustard, vitamin C
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Grade 2 Hand-foot Syndrom
Efficacy of the Cosmetic Product "Onco-Repair" on Grade 2 Hand Foot Syndrome
The aim of the study is to assess the restorative efficacy of the cosmetic product "Onco-Repair" vs placebo of the most affected palmer face in subject with grade 2 HFS induced by targeted therapies or conventional chemotherapy.
- Trial name
- OCRP (NCT03612011)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Quanta Medical
Breast Cancer
Placebo-controlled Evaluation of Cocculine® Efficacy in the Management of Nausea After Chemotherapy in Breast Cancer.
The purpose of the study is to determine whether a homeopathic remedy (Cocculine®) is effective in the prevention of chemotherapy-induced nausea in non metastatic breast cancer.
- Trial name
- NCT00409071
- Testing
- Cocculine®
- Where
- France
- Volunteers
- 431 people
- Sponsor
- Centre Leon Berard
Rheumatic Diseases, Temporomandibular Joint Dysfunction
Treatment in Individuals With Rheumatoid Arthritis Who Have Temporomandibular Joint Dysfunction
This study was conducted to investigate the effect of manual therapy applications on pain, range of motion and joint position sense in individuals with rheumatoid arthritis who have temporomandibular joint dysfunction.
- Conditions
- Rheumatic Diseases, Temporomandibular Joint Dysfunction, Manuel Therapy
- Trial name
- NCT07171671
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sanko University
Solid Tumor, Gastric Cancer
A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors
This clinical study is to investigate the safety and tolerability of CCT303-406 CAR modified autologous T cells (CCT303-406) in subjects with relapsed or refractory stage IV metastatic HER2-positive solid tumors.
- Conditions
- Solid Tumor, Gastric Cancer, Breast Cancer, Ovarian Cancer
- Trial name
- NCT04511871
- Testing
- CCT303-406
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai PerHum Therapeutics Co., Ltd.
Colorectal Cancer, Non-Small Cell Lung Cancer
A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
This study will test the safety and effectiveness of a drug called IM-1617 in participants with solid tumors. Participants will have solid tumor cancer that has spread through the body (metastatic) or cannot be removed with…
- Conditions
- Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Esophageal Cancer
- Trial name
- NCT07578571
- Testing
- IM-1617
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Immunome, Inc.
Breast Cancer
FRAGRANCE Part A Safety: Study to Find a Genetic Signature of de Novo Resistance to Letrozole
Find a genetic signature of de novo resistance to letrozole in adjuvant breast cancer;
- Trial name
- NCT00199134
- Testing
- Letrozole
- Where
- Belgium
- Volunteers
- 49 people
- Sponsor
- Jules Bordet Institute
Rheumatoid Arthritis
Umbilical Cord Tissue-derived Mesenchymal Stem Cells for Rheumatoid Arthritis
Allogeneic human umbilical cord tissue-derived stem cells will be injected intravenously once per day for 5 days is a safe and useful procedure in inducing remission of RA in patients resistant to standard DMARD therapy.
- Trial name
- NCT01985464
- Testing
- Umbilical cord mesenchymal stem cells
- Where
- Panama
- Volunteers
- 20 people
- Sponsor
- Translational Biosciences
Rheumatic Diseases, Inflammatory Arthritis
The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic Conditions
The goal of this prospective observational quality improvement study is to determine if a physician tool, MedSafer, combined with educational brochures for patients, can help to reduce the use of 'potentially inappropriate…
- Conditions
- Rheumatic Diseases, Inflammatory Arthritis, Systemic Lupus Erthematosus (SLE), Vasculitis
- Trial name
- NCT07278609
- Testing
- MedSafer deprescribing opportunity reports, EMPOWER brochures
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Arthritis, Rheumatoid
Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis
The purpose of this study is to determine the long-term effectiveness and safety of CP-690,550 for the treatment of rheumatoid arthritis.
- Trial name
- NCT00413699
- Testing
- CP-690,550
- Where
- 469 sites in United States, Argentina and 41 more
- Volunteers
- 4,488 people
- Sponsor
- Pfizer
Advanced Cancers
Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)
The goal of this clinical research study is to find the highest tolerable doses of the combinations of lenalidomide and other drugs that can be given to patients with advanced cancer.
- Trial name
- NCT01183663
- Testing
- Lenalidomide, Bevacizumab, Sorafenib
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- M.D. Anderson Cancer Center
Healthy
Tolerability Study of the Application of a 3M Microstructure Transdermal System
The purpose of this study is to evaluate the safety and tolerability of an experimental device that introduces microscopic channels into the skin.
- Trial name
- NCT01257763
- Testing
- Transdermal Microchannel Skin System
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Breast Cancer, Mastectomy; Lymphedema
Breast Reconstruction by Exclusive Lipomodulin : Feasibility, Evaluation of the Aesthetic Result and Quality of Life
Breast cancer is the leading female cancer in metropolitan France in terms of incidence and death. Among the therapeutic arsenal for the treatment of these cancers, surgery plays a very important role and even if a conservative…
- Trial name
- EXCLUFAT (NCT04625621)
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Cancer
Risk Assessment Tool in Saudi Arabia
This study will have great impact and influence in the medical setting as the targeted model that will be derived from this study will be the pioneer in our region.
- Trial name
- NCT02781116
- Where
- Saudi Arabia
- Volunteers
- 2,000 people
- Sponsor
- National Guard Health Affairs
Breast Cancer
Online Stress Management and Coping Skills Training for Women With Breast Cancer
Stress Management interventions have been shown to decrease cancer-related distress, foster emotional growth and improve immune functioning during treatment for breast cancer.
- Trial name
- NCT01335152
- Testing
- Coping with Breast Cancer web-based workbook
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Talaria, Inc
Melasma
Efficiency And Safety Of Association Arbutin, Triamcinolone And Tretinoin In Treatment Of Melasma
The objective of this study is evaluating the clinical activity of the association (tretinoin + arbutin + triamcinolone) in the treatment of epidermal melasma.
- Trial name
- melasma (NCT00717652)
- Testing
- arbutin, tretinoin, triamcinolone, Triluma
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Azidus Brasil
Breast Cancer
Adjunctive Efficacy Study Of The SoftScan® Optical Breast Imaging System
The primary study endpoint -SoftScan adjunctive accuracy- will be used to test the hypothesis that the adjunctive combination of the SoftScan with x-ray mammography provides diagnostic accuracy that is significantly better than…
- Trial name
- NCT00267449
- Testing
- SoftScan Optical Breast Imaging System
- Where
- 6 sites in United States, Canada
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- ART Advanced Research Technologies Inc.
Juvenile Idiopathic Arthritis
Open-Label Extension of the Dose Finding Study (DSC/08/2357/36) in Patients With Poly Juvenile Idiopathic Arthritis
Primary Objective of the study: the purpose of this extension study was to determine the safety of Givinostat in a long term treatment of patients who participated in DSC/08/2357/36 study with good results (clinical benefit at…
- Trial name
- NCT01557452
- Testing
- Givinostat
- Where
- Czechia
- Volunteers
- 1 people
- Sponsor
- Italfarmaco
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