Clinical trials: Normal Volunteers
Healthy
Safety, Pharmacokinetics, and Pharmacodynamics of SD-101 in Healthy Normal Males
The main purpose of this study is to assess the safety, tolerability, and biological activity of SD-101 compared with placebo in healthy male volunteers.
- Trial name
- NCT00599001
- Testing
- SD-101
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Dynavax Technologies Corporation
Anxiety Disorder, Head Injury
Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning…
- Conditions
- Anxiety Disorder, Head Injury, Mood Disorder, Schizophrenia
- Trial name
- NCT00001192
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Ovarian Cancer, Healthy Volunteers
Safety and Biodistribution of Technetium Tc 99m EC20 in Normal Volunteers and Ovarian Cancer Patients
Open-label, single-center, single-treatment group, baseline-controlled (for safety) study of the safety and biodistribution of Technetium Tc 99m EC20 in four normal subjects and four subjects with known or suspected ovarian…
- Trial name
- NCT01689636
- Testing
- Tc 99m EC20
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Endocyte
Pruritus
Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance P
The purpose of this study is to test whether VLY-686 can prevent or reduce the itch and dermatological reaction observed after healthy volunteers are injected with Substance P in comparison with placebo.
- Trial name
- NCT01919944
- Testing
- VLY-686
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Microbiome of the Axillae
Effects of a Zinc Oxide Underarm Formula on Normal and Injured Skin in Healthy Volunteers
Bothersome odor from the axilla is in most cases caused by Corynebacterium spp. Anti-microbial effects of zinc oxide (ZnO) are well documented.
- Trial name
- ZINC-ON (NCT03221699)
- Testing
- Formula with ZnO, Formula without ZnO
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lars Nannestad Jorgensen
Acne Vulgaris
A Phase 1, 3 Day Study of Safety and Tolerability of NVN1000 Topical Gel in Healthy Volunteers
A Phase I, Single-Center, Open-Label, Randomized, Parallel Group, 3 Day Study Evaluating the Safety and Cutaneous Tolerability of NVN1000 Topical Gel in Healthy Volunteers
- Trial name
- NCT01755247
- Testing
- Topical Gel Vehicle, 8% NVN1000 Topical Gel, 8% NVN1000 Topical Gel and moisturizer
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Acne Vulgaris
A Safety, Tolerability, Efficacy and Exposure Study of XEN801 Topical Gel
Phase 1/2 study enrolling up to 60 healthy volunteers in Phase 1 followed by approximately 150 subjects with acne vulgaris in Phase 2.
- Trial name
- NCT02656043
- Testing
- XPF-005
- Where
- 20 sites in Canada
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Xenon Pharmaceuticals Inc.
Healthy Tissue, Muscles
Deep Optical Imaging of Tissue (DOIT)
In medical imaging, X-ray-based methods are widely used, which means that patients are exposed to ionizing radiation. In addition, invasive tissue samples often need to be taken with biopsy needles to, for example, safely…
- Conditions
- Healthy Tissue, Muscles, Extremity, Breast
- Trial name
- DOIT (NCT07754500)
- Testing
- Mk1
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University
Bone Marrow Stromal Cells
Collection of Bone Marrow From Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) Products
Background: Bone marrow stromal cells (BMSCs) can be grown from bone marrow provided by healthy volunteers. Volunteer bone marrow donors for BMSCs are generally required to meet the same healthy history and infectious disease…
- Trial name
- NCT01071577
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Volunteers, Sepsis
The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation
Severe sepsis still carries a high mortality rate despite advantages in intensive care medicine and antimicrobial therapy. The inflammatory and procoagulant host response to infection are intricately linked and interactions…
- Trial name
- NCT01099566
- Testing
- Prasugrel
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Allergic Conjunctivitis
Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
The purpose of this study is to evaluate the safety of a novel contact lens in healthy normal volunteers
- Trial name
- NCT00569777
- Testing
- K-Lens (generic name not established) and Ketotifen
- Where
- 3 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Vistakon Pharmaceuticals
Tuberculosis, HIV
Collection of Tissue Specimens in Mali, West Africa, for HIV and Tuberculosis Research
This study, conducted in Bamako, Mali (West Africa), will collect blood and sputum samples to establish normal values for laboratory test results among Malians.
- Trial name
- NCT00341042
- Where
- Mali
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atopic Dermatitis
A First-in-Human Study of CEE321 in Adult Subjects
Open label, non-randomized, uncontrolled, First-in-Human Phase 1 Study in Healthy Subjects and Subjects with Atopic Dermatitis
- Trial name
- NCT04612062
- Testing
- CEE321
- Where
- 3 sites in United States, Japan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Healthy
Study to Investigate the Safety and Immunogenicity of a Tetravalent Chimeric Dengue Vaccine in Healthy Volunteers Between the Ages of 1.5 - 45 Years
The purpose of this study is to assess the safety of Takeda's tetravalent dengue vaccine (TDV) (previously DENVax) administered subcutaneously in healthy adults and children.
- Trial name
- NCT01511250
- Testing
- TDV
- Where
- 8 sites in Colombia, Puerto Rico and 2 more
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy Volunteers
Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule Under Fed Condition
The objective of the study is to compare the bioavailability and characterise the pharmacokinetic profile of Mycophenolate mofetil 250 mg capsules Panacea Biotech Ltd, India and Cellcept® 250 mg capsules Mycophenolate mofetil…
- Trial name
- NCT01080417
- Testing
- Mycophenolate Mofetil Capsule 250 mg
- Where
- India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Panacea Biotec Ltd
Healthy Volunteers, Effect of CPAP on Chest Movement
Effect of CPAP on Breath Hold and Chest Movement in Normal Volunteers
CPAP will be applied to normal volunteers inorder to understand CPAP's effects on breathing and chest wall motion.
- Trial name
- CPAP_normal (NCT02545686)
- Testing
- Chest wall movement assessment without CPAP, Breath hold assessment without CPAP, Chest wall movement assessment with CPAP
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Asthma
Phase1, Placebo-Controlled, Randomized, Double-blind, Single-ascending Dose Study in Healthy Subjects.
To evaluate the safety and tolerability of S-1226 composed of perflubron with ascending doses of carbon dioxide (4%, 8%, and 12% CO2) administered over 2 minute nebulisation to healthy subjects.
- Trial name
- NCT02616770
- Testing
- S1226 (4%), Saline (for 4%), S1226(8%)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- SolAeroMed Inc.
Dystonic Disorder, Healthy
Transcranial Magnetic Stimulation (TMS) Studies of Dystonia
This study will use transcranial magnetic stimulation to examine how the brain controls muscle movement in focal and generalized types of dystonia.
- Trial name
- NCT00017875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a phototoxic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01115322
- Testing
- Tazarotene Foam without irradiation, Tazarotene Foam with UVA and UVB irradiation, Tazarotene Foam with UVA, UVB, and visible light
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Oxygen Deficiency
Validation of Next Generation Cerebral and Tissue Oximeter
This is a validation study of a near-infrared spectroscopy (NIRS) device designed to measure the cerebral tissue oxygen saturation.
- Trial name
- NCT03128372
- Testing
- Desaturation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
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