Clinical trials: Normal Weight
Obesity, Appetitive Behavior
Comparing EVCO and EVOO
The aim of this study is to compare acute effects of consuming extra virgin coconut oil (EVCO) as a source of medium chain fatty acids and extra virgin olive oil (EVOO) as a source of long chain fatty acids in normal weight and…
- Trial name
- NCT04738929
- Testing
- Extra virgin coconut oil or extra virgin olive oil
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Newborn Morbidity, Newborn Complication
Cord Blood Preptin Levels in Infants
In this study, cord blood preptin levels in infants with high or low birth weight will be compared to those in infants with normal birth weight.
- Trial name
- NCT06880003
- Testing
- During delivery, blood samples will be collected from the umbilical cord
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Osteoarthritis, Knee, Chondral Defect
Evaluation of Treatment of Osteoarthritis of the Knee in the Form of Chondromalacia of the Articular Cartilage Treated in the Arthroscopic Technique With the Use of:Autogenous Transplantation of Fragmented Adipose Tissue,PRP GF,Mesenchymal Cells,Hyaluronic Acid-low Molecular Weight and Cross-linked
The main objective of the research project is to evaluate the results of the treatment of chondromalacia of the cartilage in the knee joint with the use of: autogenous transplantation of fragmented adipose tissue taken from the…
- Conditions
- Osteoarthritis, Knee, Chondral Defect, Chondromalacia, Left Knee, Chondromalacia, Right Knee
- Trial name
- NCT07110402
- Testing
- Autogenous transplant of fragmented adipose tissue taken from abdominal integuments, PRP GF (platelet-rich plasma with growth factors), Mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- eMKa MED Medical Center
Obesity, Inflammation
Effects of Different Coffee Amounts on Energy Intake, Appetite, Glucose Metabolism and Inflammatory Markers
The purpose of the study is to investigate whether different doses of caffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and…
- Trial name
- NCT01495754
- Testing
- coffee
- Where
- Greece
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Asthma Bronchiale, Breast Neoplasms
Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity
The web application gp-multitool.de is a digital tool for implementing the German S3 clinical practice guideline for multimorbidity of the German Society of General Practitioners and Family Physicians in primary care.
- Conditions
- Asthma Bronchiale, Breast Neoplasms, Coronary Disease, Diabetes Mellitus, Type 2
- Trial name
- NCT06831994
- Testing
- gp-multitool.de
- Where
- Germany
- Volunteers
- 659 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Breast Cancer
Weight Loss Plus Omega-3 Fatty Acids or Placebo in High Risk Women
The purpose of this study is to determine if high dose supplementation with the omega-3 fatty acids EPA and DHA, when added to a weight loss program, is well tolerated in the study population and if there is an increase in the…
- Trial name
- NCT02101970
- Testing
- Omega-3 Fatty Acids, Diet and Exercise
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Whole Body Imaging, Magnetic Resonance Imaging
Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Whole body MRI will be performed in patients with neurofibromatosis Type 1 PURPOSE 1: To determine the total tumor load (neurofibroma) and to diagnose plexiform neurofibromas or malignant peripheral nerve sheath tumors.
- Conditions
- Whole Body Imaging, Magnetic Resonance Imaging, Neurofibromatosis 1, Diffusion Magnetic Resonance Imaging
- Trial name
- NEFIMAR (NCT01777451)
- Testing
- Additional imaging or surgery
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity
Longitudinal Follow-up of Brown Adipose Tissue Function and Structure
In Turku PET Centre, there have been 3 positron emission tomography studies on brown adipose tissue (BAT) activity in healthy adults. BATPET was performed between 2008 and 2009.
- Trial name
- BATFollowUp (NCT01985503)
- Where
- Finland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin…
- Conditions
- Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis, Chronic Inflammation
- Trial name
- NCT04232566
- Testing
- Bariatric surgery
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer, Overweight or Obesity
Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study
This is a single arm phase II study designed to determine the effects of pharmacotherapy and a remote behavioral weight loss intervention on weight loss in breast cancer survivors who are overweight or obese, and the impact of…
- Trial name
- A-NEW (NCT04499950)
- Testing
- Contrave, Behavioral Weight Loss
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Obesity
Beta-glucan and Insulin Sensitivity in Obese Humans
Obesity is an important health problem of modern civilization. In Western societies, almost half of the adult population has problems with an increased body weight.
- Trial name
- NCT01393210
- Testing
- low calorie diet plus beta-glucan, low-calorie diet
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Marek Straczkowski
Obese
Monounsaturated Fatty Acids and Brown/Beige Adipose Tissue in Humans
Considering the high prevalence of obesity its comorbidities in Brazil and in the world, different therapeutic measures have been suggested.
- Trial name
- NCT03024359
- Testing
- Extra virgin olive oil
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Pregnancy; Nutritional Diseases
Growth and Adiposity in Newborns: The Influence of Prenatal Docosahexaenoic Acid (DHA) Supplementation
The purpose of this study is to learn if participants in the ADORE study (NCT02626299), who took a DHA supplement during pregnancy, see favorable body fat in their infants from birth to 24 months, and if excessive or appropriate…
- Trial name
- ADORE-GAINS (NCT03310983)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Obesity
Study of the Effect of Vagus Nerve Stimulation on Human Brown Adipose Tissue Activity
To evaluate the effect of vagus nerve stimulation for refractory epilepsy on the activity of human brown adipose tissue.
- Trial name
- NCT01491282
- Testing
- Enabling and disabling VNS
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Maastricht University
Pregnancy Complications, Maternal Obesity
Gasdermin-D and Pannexin-1 in Pregnancy
One -third of fertile women around the world are overweight or obese. This means increasing risk for both the mother and the child.
- Trial name
- NCT05475951
- Testing
- Biomarker measurement of pannexin-1 and gasdermin-D
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Healthy, Obese
Exercise Regulation of Human Adipose Tissue
The purpose of this study is to determine whether exercise training leads to changes in the white adipose tissue that are beneficial to the body's regulation of sugar and body weight.
- Conditions
- Healthy, Obese, Diabetes Mellitus, Type 2
- Trial name
- NCT03133156
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Breast Cancer, Primary Hormone Receptor Positive Breast Cancer
A Study of the Body's Response to Exercise and a Plant-Based Diet in Overweight Postmenopausal Women With Breast Cancer
The purpose of this study is to find out what effects, if any, exercise and a plant-based diet have on aromatase levels in postmenopausal women who are overweight and being treated with an aromatase inhibitor for their HR+ breast…
- Trial name
- NCT04298086
- Testing
- Exercise Treatment, Plant-Based Diet, Physical activity
- Where
- 7 sites in United States
- Volunteers
- 43 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
End-Stage Kidney Disease, Hemodialysis
Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients
This is a prospective, randomized, double-blind, parallel group trial to assess the efficacy and safety of intravenous dextrose 5% solution compare with normal saline (standard care) in wash back procedure during haemodialysis in…
- Trial name
- NSD5 (NCT02590081)
- Testing
- Dextrose 5%, normal saline
- Where
- 15 sites in Malaysia
- Volunteers
- 434 people
- Sponsor
- Penang Hospital, Malaysia
Breast Cancer, Insomnia
The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
The investigators propose a randomized controlled clinical trial in 250 women with a history of early stage breast cancer who are overweight or obese with insomnia to test whether a brief, cognitive-behavioral intervention for…
- Conditions
- Breast Cancer, Insomnia, Weight Gain
- Trial name
- COIN (NCT05780814)
- Testing
- Cognitive-Behavioral Therapy for Insomnia (CBT-I), Sleep Education Control (EDU)
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins University
Obesity, Overweight and Obesity
Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
Obesity, affecting 40% of US adults and costing 173b annually, represents a significant health care burden (1). It is associated with increased risk for multiple chronic diseases including hypertension, type 2 diabetes (T2D)…
- Conditions
- Obesity, Overweight and Obesity, Overweight
- Trial name
- NCT05912621
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University