Clinical trials: Normobaric Hypoxia
High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N)
Normobaric Hypoxia as a Strength Training Intensity Amplifier in Ice Hockey Players: Effects on Anaerobic Performance and Muscle Contraction Properties
The goal of this research study is to investigate the effects of resistance training performed under normobaric hypoxia (simulated altitude conditions) on anaerobic performance, lactate clearance, and muscle contractility in…
- Conditions
- High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N), High-intensity Strenght Training in Normobaric Hypoxia (H-H), Low-intensity Strenght Training in Normobaric Hypoxia (L-H)
- Trial name
- NCT06930027
- Testing
- Resistance Training (High-Intensity), Resistance Training (Low-Intensity), Normobaric Hypoxia
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Hypertension, Pulmonary
Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension Receiving Sildenafil
To study the effect of acute normobaric hypoxia during exercise in patients with pulmonary hypertension with/without Sildenafil
- Trial name
- HEXASH (NCT04697862)
- Testing
- Normobaric hypoxia (FiO2 15%) under Sildenafil, Normobaric hypoxia (FiO2 15%)
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Hypoxia, Hypoxia Brain
Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory.
The goal of this study is to investigate whether prospective memory, i.e., memory for delayed intentions, is impaired at moderate altitude (4,000m).
- Conditions
- Hypoxia, Hypoxia Brain, Hypoxia Altitude Simulation Test, Hypoxia in Healthy Individuals
- Trial name
- HYPRO (NCT07585227)
- Testing
- Hypoxia exposure, Oxygen administration, Air administration
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Overweight, Healthy
Effects of Normobaric Hypoxia and Different Exercise Modes on Blood Glucose Regulation in Overweight Adults
Obesity is a major global health issue and a primary risk factor for metabolic-related disorders. While physical inactivity is one of the main contributors to obesity, it is a modifiable risk factor with exercise training as an…
- Conditions
- Overweight, Healthy, Physical Inactivity
- Trial name
- NCT05627804
- Testing
- Low-moderate intensity exercise, Sprint interval training, Functional exercise
- Where
- Malaysia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Swinburne University of Technology
Hypoxia, Bone Resorption
Planetary Habitat Simulation: Bone Metabolism Studies
Bone losses are well known to occur in response to unloading (in microgravity or during immobilisation) and in patients with chronic obstructive airway disease (COPD).
- Trial name
- PlanHab (NCT02637921)
- Testing
- Hypoxia, Ambulatory, Normoxia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Peripheral Arterial Disease
Hypoxic Exercise in Lower Extremity Artery Disease
The aim of this randomized controlled trial is to: Phase I: To explore, in a first pilot phase, the adequate combination of hypoxia severity and exercise intensity in patients with symptomatic lower extremity artery disease…
- Trial name
- NCT03506607
- Testing
- Exercise in hypoxia 1500m, Exercise in hypoxia 2500m, Exercise in normoxia
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Hypoxia, Normobaric Hypoxia
The Impact of Hypoxia on the Biochemical and Morphological Parameters of Blood in Rowers.
The response to hypoxia is very individual and depending on many aspects, such as the type of training, duration, intensity, or hypoxic stimulus, hypoxia affects the athlete in various ways.
- Trial name
- IHOBMPBR (NCT06264193)
- Testing
- Normobaric hypoxia (LHTL)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Hypertension, Pulmonary
Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension With/Without Sildenafil
To study the effect of acute normobaric hypoxia during exercise in patients with pulmonary hypertension with/without Sildenafil
- Trial name
- HEXAS (NCT04704440)
- Testing
- Normobaric hypoxia (FiO2 15%), Normobaric hypoxia (FiO2 15%) under Sildenafil
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Hypoxia
Repeated Sprint Training in Normobaric Hypoxia
The aim of the current study was to examine the effects of 3-session repeated sprint training performed in a normobaric hypoxic condition with 48-hour rest intervals on sprint performance indices, arterial oxygen saturation…
- Trial name
- NCT05967767
- Testing
- Normobaric Hypoxia Exposure, Normobaric Normoxia Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara University
Body Temperature Changes, Heat Stress
Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain
Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers performing physically demanding work in hot environments.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07664462
- Testing
- Simulated Occupational heat exposure under normoxic conditions, Simulated Occupational heat exposure under hypoxic conditions
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Ottawa
Acute Mountain Sickness
Prevention of Acute Mountain Sickness by Intermittent Hypoxia
Acclimatization by mountaineering prior to high altitude sojourns have shown to be effective in prevention of acute mountain sickness (AMS).
- Trial name
- NCT00559832
- Testing
- Hypoxic Exposure
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Obesity
Low Oxygen Exposure and Weight Status
The objective of the proposed double-blind, parallel-arm, randomized clinical trial is to evaluate changes in body weight and composition, assess determinants of energy balance (intake and expenditure), and measure modulators of…
- Trial name
- LOWS (NCT05289310)
- Testing
- Normobaric hypoxia (NH), Normobaric normoxia (NN)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Normobaric Hypoxia, Hypoventilation
Influence of Hypoxic, Normobaric and Hypobaric Training on the Immunometabolism of Post-covid-19 Athletes
COVID-19 has significantly impacted sports globally, with event postponements, training disruptions, and wide-ranging concerns. SARS-CoV-2 infection can result in hyperinflammation and cardiopulmonary changes, with hypoxia as an…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06128941
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Hypoxia-Ischemia, Brain, Ischemia, Vertebral Artery
Oxygen Concentration and Recovery After Carotid Endarterectomy
This study evaluates effects of high inspiratory oxygen on cerebral tissue oxygenation and patient recovery after carotid endarterectomy.
- Conditions
- Hypoxia-Ischemia, Brain, Ischemia, Vertebral Artery, Artery Stenosis, Carotid
- Trial name
- NCT02991976
- Testing
- Oxygen concentration
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- Osijek University Hospital
Overweight and Obesity
Daily Low Oxygen Exposure and Weight Status
The objective of this single-blind, parallel-arm, randomized clinical trial is to evaluate changes in body weight and composition, assess determinants of energy balance, and measure modulators of energy intake and expenditure…
- Trial name
- LOWS (NCT04801810)
- Testing
- Normobaric hypoxia, Normobaric normoxia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Florida State University
Stroke, Acute, Hypoxia-Ischemia, Brain
Normobaric Hyperoxia Combined With Endovascular Therapy in Patients With Stroke Within 6 Hours of Onset：Longterm Outcome
The overall incidence of good outcome for AIS following endovascular treatment is only proximately 50%. Whether NBO was safe and effective to improve acute ischemic stroke prognosis is still unclear.
- Conditions
- Stroke, Acute, Hypoxia-Ischemia, Brain, ENDOVASCULAR TREATMENT
- Trial name
- NBOL (NCT05039697)
- Testing
- oxygen
- Where
- China
- Volunteers
- 282 people
- Sponsor
- Capital Medical University
Healthy, Heart Disease
Effect of Training in Normobaric Hypoxia on Cardiac Markers
The goal of this study is to determine changes in the concentration of cardiac biomarkers in blood in response to a single bout of exercise performed until volitional exhaustion under hypoxic conditions, and in response to…
- Trial name
- HYPO-CARDIAC (NCT06896773)
- Testing
- Impact of Normobaric Hypoxia on Cardiac Biomarkers in trained men, Effects of Hypoxic Endurance Training on Cardiac Biomarkers in the IHT group, Effects of Hypoxic Strength Training on Cardiac Biomarkers in the NRT group
- Where
- Poland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Hypoxia, Altitude, Exercise
Oxygen Transport in Normobaric vs. Hypobaric Hypoxia
1) Oxygen Transport in Normobaric versus Hypobaric Hypoxia. 2) The purpose of this study is to examine acute responses in arterial and muscle tissue oxygenation during incremental exercise in normobaric versus hypobaric hypoxia.
- Trial name
- NCT03335917
- Testing
- Hypoxia, Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Hypertension, Pulmonary
Hemodynamic Effects During Exercise in Patients With Pulmonary Hypertension Receiving Sildenafil
To study hemodynamic effects of Sildenafil during exercise in patients with pulmonary hypertension.
- Trial name
- HEXASN (NCT04706546)
- Testing
- Hemodynamic effect of exercise under Sildenafil, Hemodynamic effect of exercise
- Where
- 2 sites in Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Cardiac Output, Stroke Volume
Exercise Induced Plasma Volume Expansion Lowers Cardiovascular Strain
The goal of this observational study was to better understand the impact of increased plasma volume on later exercise in hypoxia. Investigators examined young, healthy, males who regularly participated in aerobic exercise.
- Trial name
- NCT05800808
- Testing
- High Intensity Intervals, Moderate Exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- California Baptist University