Clinical trials: Nosocomial Infections
Clostridioides Difficile Infection, Healthcare Associated Infection
Evaluation of GeoHAI Implementation
Geographic Information Systems (GIS) and spatial analysis have become important tools in public health informatics but have rarely been applied to the hospital setting.
- Trial name
- NCT05612672
- Testing
- GeoHAI
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Nosocomial Infections
ED Residents MBP During CVC Placement: Sim Lab Based Training
1. Baseline performance in maximal barrier precaution technique of Emergency Medicine (EM) residents, certified in CVC placement, is poor 2.
- Trial name
- EM CVC MBP (NCT00791583)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Influenza
Asymptomatic Flu Project
Although clinical presentation of influenza is often symptomatic, asymptomatic cases also occur. The knowledge of the incidence of asymptomatic influenza among healthcare workers is very important because of the risk of…
- Trial name
- AFP (NCT02868658)
- Testing
- Blood sampling, Nasal swab
- Where
- France
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Inflammatory Response, Multi Organ Failure
Association of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis (TENS) Patients
This study will involve blood draws to test for specific cytokines. The study goal is to gain a better understanding of the role of inflammatory response in the development of specific complications in burn and TENS patients.
- Conditions
- Inflammatory Response, Multi Organ Failure, Nosocomial Infection, Deep Vein Thrombosis
- Trial name
- NCT04252651
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Joseph M. Still Research Foundation, Inc.
Nosocomial Pneumonia
The Role of Point-of-care Polymerase Chain Reaction in Managing Nosocomial Pneumonia
The study compares a device that is used for the detection of bacteria and MDR pathogens from skin, soft tissue and nose with the gold-standard (microbiological lab).
- Trial name
- NCT05928208
- Testing
- no intervention
- Where
- Romania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pseudomonas Aeruginosa, Colonization, Asymptomatic
Carbapenem-resistant Pseudomonas Aeruginosa: the SAMPAN Study.
Pseudomonas aeruginosa causes severe infections in hospitalized patients. The worldwide emergence of carbapenem-resistant P. aeruginosa (CRPA) makes infections by these pathogens almost untreatable.
- Conditions
- Pseudomonas Aeruginosa, Colonization, Asymptomatic, Nosocomial Infection
- Trial name
- SAMPAN (NCT05282082)
- Where
- 3 sites in Indonesia, Italy and 1 more
- Volunteers
- 2,105 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Nosocomial Infection
Evaluation of Body-worn Multimodal Hand Hygiene System. Impact on Health-Care Associated Infections
Evaluate the efficacy of a multimodal hand hygiene system in the intensive care unit environment and evaluate any impact on health care associated infections.
- Trial name
- Sprixx-ICU (NCT01050608)
- Testing
- Body worn alcohol gel dispenser, 62% ethanol based hand cleanser, Educational component with regard to teaching CDC guidelines
- Where
- United States
- Volunteers
- 2,954 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Catheter-Associated Infection
Clinical Evaluation of Copesilcup
Healthcare-associated infections (HAIs): HAIs are a problem for all institutions and countries worldwide. Currently, one of the main infections is catheter-associated urinary tract infection (CAUTI).
- Trial name
- Copesilcup (NCT07530328)
- Testing
- PEGylated Silicone Urinary Catheter with Copper Nanoparticles (COPESILCUP), Control Device
- Where
- Chile
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- WMAS SpA
Influenza, Influenza Prophylaxis
Oseltamivir and Baloxavir Marboxil for Prophylaxis Against Influenza Under a Hospital-based Setting
This study aims to randomly assign close contacts of hospitalized influenza virus patients to receive baloxavir marboxil prophylaxis, oseltamivir prophylaxis or no antiviral prophylaxis and monitor the incidence of clinical…
- Conditions
- Influenza, Influenza Prophylaxis, Nosocomial Infection
- Trial name
- NCT06762587
- Testing
- Baloxavir Marboxil, Oseltamivir
- Where
- China
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Death, Nosocomial Infection
Prophylactic Probiotics in Premature Infants
This study tries to determine whether the oral administration of a specific probiotic (good bacteria) in premature infants hospitalized in a neonatal intensive care unit may prevent infections and the development of a severe…
- Trial name
- C3P (NCT00727363)
- Testing
- Lactobacillus reuteri
- Where
- 8 sites in Colombia
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Colombian Neonatal Research Network
Children, Only, Educational Problems
Toy Hygiene Education For Hospitalized Mothers
The present study aims to evaluate the effectiveness of toy hygiene education given to mothers of hospitalized children on their knowledge and practices, as well as the cleanliness of toy surfaces.
- Conditions
- Children, Only, Educational Problems, Hospital Infection
- Trial name
- NCT06199804
- Testing
- Toy Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sibel Küçükoğlu
COVID-19
COVID-19 Infection in Healthcare Workers
Introduction: The SARS-Cov-2 outbreak in France and the concomitant massive increase in the number of cases requiring hospital management create a major risk of COVID-19 infection for hospital staff.
- Trial name
- HOP-COVID (NCT04386759)
- Testing
- Cohort
- Where
- France
- Volunteers
- 1,858 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Influenza
Study to Evaluate Nosocomial Transmission of Influenza
The purpose of this study is to investigate whether influenza can be reliably transmitted from children to susceptible contacts in a health care setting.
- Trial name
- NCT00798421
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Hospital Infection, Standardized Antibiotic Prescribing Ratio (SAR)
InPART RX - Epicenters
InPART Rx is a collaborative research study to measure the impact of a planned quality improvement initiative to reduce unnecessary antibiotic prescribing by the Hospital Medicine Service through a process of receiving…
- Trial name
- InPART RX (NCT07368660)
- Testing
- Messaging Hospitalists, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Emory University
Patient With Influenza Like Illness
Effect of Influenza Vaccination of Healthcare Workers (HCW) on the Risk of Influenza in Patients Hospitalized in Short Stays Units
Hospital acquired influenza is associated with significant morbidity and mortality in hospitalized patients notably elderly patients. Vaccination of HCW is recommended to prevent influenza transmission in healthcare setting.
- Trial name
- NCT02198638
- Testing
- A nasal swab
- Where
- 2 sites in France
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Nosocomial Infections
Nosocomial Respiratory Virus Infection
Hospital-acquired Viral Respiratory Infections (HAVRI) are associated with substantial burden on health care systems. The prevention and control of these viral infections rely on multiple measures such as hand hygiene or wearing…
- Trial name
- NOSOVIRUS (NCT06643039)
- Testing
- Nasopharyngeal swab, Questionnaire
- Where
- 6 sites in France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthcare Associated Infection, Hand Hygiene
Effect of Video Camera Monitoring Feedback on Hand Hygiene Compliance and Infections in NICU
The purpose of this study is to determine if use of the video camera surveillance system for HH observation and performance feedback about HH compliance rates can improve the HH compliance of HCWs and reduce healthcare-associated…
- Conditions
- Healthcare Associated Infection, Hand Hygiene, Neonatal Infection
- Trial name
- CaM-HAI (NCT04053257)
- Testing
- Hand hygiene compliance observation with video camera surveillance system and performance feedback of the HH rates to HCWs
- Where
- Turkey (Türkiye)
- Volunteers
- 8,335 people, healthy volunteers welcome
- Sponsor
- Marmara University
Infection
Use of Provodine to Protect HCW Hands (Aim II.1)
The investigators will assess whether applying Provodine, an FDA-approved hand hygiene product with a long duration of anti-microbial action, to healthcare workers' hands protects against self-contamination during the removal of…
- Trial name
- NCT03972826
- Testing
- Provodine
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Infection Viral
COVID-19 - Multicentre Study on Nosocomial Transmission of SARS-CoV-2 Virus: an Ancillary Study (NOSO-COR IMMUNO)
There are still uncertainties about the existence of protective immunity and the duration of protective antibodies in patients infected with SARS-CoV-2.
- Trial name
- NCT04637867
- Testing
- Collection of blood, salivary and nasopharyngeal samples.
- Where
- 2 sites in France
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Coronavirus Infections, Healthcare Associated Infection
NO Prevention of COVID-19 for Healthcare Providers
Thousands of healthcare workers have been infected with SARS-CoV-2 and contracted COVID-19 despite their best efforts to prevent contamination. No proven vaccine is available to protect healthcare workers against SARS-CoV-2.
- Trial name
- NOpreventCOVID (NCT04312243)
- Testing
- Inhaled nitric oxide gas
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital