Clinical trials: Novel Algorithm
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Inflammatory Bowel Disease, Crohn Disease
Deep Endoscopic Remission Assessed by a Surrogate Biomarker in Patients With Inflammatory Bowel Disease
We hypothesize that the number of needed endoscopic procedure performed at IBD patients (adult and children), can be reduced by using an individualized algorithm of symptoms, blood and faecal biomarkers.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT01861288
- Where
- Denmark
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Healthy
The Evaluation of a New Sleep Algorithm
A new device is being developed to screen for sleep-breathing disorders. Within this device is a new software algorithm which will determine sleep/wake states.
- Trial name
- NCT01925430
- Testing
- Screening device, Comparative product
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- ResMed
Gait, Stumbling, Gait, Perturbation
Mimicking Slipping Responses Using a Novel Mechanical Perturbation Algorithm
Healthy subjects will be invited to fill out a questionnaire regarding falls and balance skills followed by normal walking trials on a treadmill at 9 different speeds (0.28-1.4 m/s).
- Trial name
- NCT05890755
- Testing
- Mechanical pertubation
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Peripheral Arterial Disease
Validation of a Novel Oscillometric-Based Algorithm for Determination of the Ankle-Brachial Index
Peripheral arterial disease (PAD) is a highly prevalent medical condition. Patients with PAD are usually diagnosed on the basis of the ankle-brachial index.
- Trial name
- NCT01165437
- Testing
- Blood Pressure Measurement
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Summit Doppler Systems, Inc.
Alcohol Drinking, Alcohol Intoxication
Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms
The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing…
- Trial name
- NCT05692830
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
ADHD
A Comparative Study to Evaluate a Novel Algorithm As a Diagnostic Aid for ADHD in Youth Ages 6-17.
This study aims to demonstrate the accuracy of the MT1 algorithm using the MindTension biometric sensor device as a diagnostic aid for healthcare providers in diagnosing ADHD in youth ages ≥ 6 to ≤17 years.
- Trial name
- NCT06728969
- Testing
- MT1 Auditory startle response patterns analysis algorithm, T.O.V.A. Continuous Performance Test
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MindTension
Epilepsies
Role of High-Frequency Oscillations on Scalp EEG in Identifying Epileptogenic Activity in Patients With Epilepsy and Healthy Controls
This observational case-control study aims to evaluate whether high-frequency oscillations (HFOs) detected on scalp electroencephalography (EEG) can differentiate patients with epilepsy from healthy controls.
- Trial name
- NCT07470931
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Delirium
With the Development of Research, New Algorithms and Technologies Have Emerged, One of Which is Machine Learning. Machine Learning Can Extract Key Factors From Vast Amounts of Data, Identify Underlying Patterns, and Predict Future Trends. In Recent Years, Machine Learning Has Been Widely Used in
The aim of this study is to construct a predictive model for postoperative delirium in elderly patients with hip fractures. The main question it answers is to construct a risk prediction model for hip fractures in the elderly…
- Trial name
- POD (NCT07121309)
- Where
- China
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University
Health, Subjective
Thermographic Analysis of Hemodynamics Changes Through & Following Wingate Test
Remote sensing and measurements of hemodynamic changes in blood flow for Wingate Anaerobic test using a novel image processing algorithm.
- Trial name
- NCT05361876
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Atherosclerosis, Wounds and Injuries
Machine Learning for Handheld Vascular Studies
The use of handheld arterial 'stethoscopes' (continuous wave Doppler devices) are ubiquitous in clinical practice. However, most users have received no formal training in their use or the interpretation of the returned data.
- Trial name
- DopplerZAM (NCT02932176)
- Testing
- Non-invasive vascular testing, machine-learning algorithm
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Duke University
Static and Dynamic Posture Standards
Posture Standards of a New Dynamic Platform
The objective is the determination of norms on healthy subjects, by age groups (20-29/30-39/40-49/50-59/60-69/70-79/80-89 years) for the posturological evaluation of four posture tests: the sensory organization test, the motor…
- Trial name
- VESTINORM (NCT05532176)
- Testing
- Posture standards
- Where
- France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Pregnancy Complications, Endothelial Dysfunction
Oxidative Stress and Endothelial Function in Pregnancy Complications
Pregnancy complications like pre-eclampsia (PE), pregnancy induced hypertension (PIH), intra-uterine growth restriction (IUGR) and preterm labor (PTL), (i.e.
- Trial name
- ENDOPREG (NCT02603913)
- Where
- Belgium
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Pancreatic Cancer
Epigenomic and Machine Learning Models to Predict Pancreatic Cancer
The goal of the multicentric and interdisciplinary IMAGene project is to pursue early diagnosis for Pancreatic Cancers in high-risk asymptomatic subject groups, by developing and validating a comprehensive cancer risk prediction…
- Trial name
- IMAGene (NCT06334458)
- Testing
- Early diagnosis for Pancreatic Cancers in high-risk asymptomatic subject groups
- Where
- 4 sites in France, Italy and 2 more
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Early Warning Score
The New Golden Standard: the Early Warning Score Algorithm
The objective is this study is the development and implementation of a smart algorithm to compute an early warning indicator able to predict early patient deterioration.
- Trial name
- EAGLE (NCT04292158)
- Testing
- SomnoTouch, MOX
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Liege
Diabetes
Study to Test Software Algorithm for Insulin Therapy and New Glucose Sensor
To investigate the performance of a software-algorithm based insulin therapy to control blood glucose in Type 1 diabetic patients.
- Trial name
- NCT01781533
- Testing
- algorithm
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Breast Cancer
Personalized Breast Cancer Screening
The purpose of the study is to measure short-term safety and efficacy of personalized vs. standard mammography screening among 50-67-year aged women.
- Trial name
- PRSONAL (NCT06060938)
- Testing
- Risk stratified arm, Control arm
- Where
- Denmark
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Software Evaluation for Visualizing Anatomical Structures Not Typically Identified on Clinical MR Images
Accuracy Evaluation of SIS Software-based Visualization of New Anatomical Brain Structure
SIS has developed a software technology, based on machine learning and image processing, designed to enhance standard clinical images for the visualization of anatomical structures.
- Trial name
- NCT04814277
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Surgical Information Sciences Inc.
Myopia, Astigmatism
New Treatment Algorithm to Reduce Spherical Aberration After LASIK Correction for Myopia
The purpose of this clinical trial is to demonstrate that treatments generated by an investigational algorithm reduces spherical aberration compared to currently available iDesign treatments.
- Trial name
- NCT01988415
- Testing
- VSS-Rx1 OPM vs Commercial iDesign Treatment
- Where
- Colombia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cognitive Dysfunction, Stroke
Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling…
- Conditions
- Cognitive Dysfunction, Stroke, Dementia, Depression
- Trial name
- VESPAR (NCT05649800)
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Leicester