Clinical trials: Nulliparous
IUD Insertion Complication
Pain Management Associated With the Insertion of Jaydess® in Nulliparous Women
A multicenter prospective interventional comparative study that investigate pain management during Jaydess insertion in nulliparous women that will be tested by the analgesic affects of oral tramadol or 'verbal anesthesia' on the…
- Trial name
- Jaydess (NCT02706509)
- Testing
- Tramadol, Verbal anesthesia, Jaydess
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Fetal Macrosomatia, Lipid Metabolism Disorders
Influence of TyG Index and TG/HDL-C Ratio on Fetal Macrosomia
Metabolic disorders that can occur during pregnancy, in particular disorders of lipid metabolism and insulin resistance, can have a detrimental effect on pregnancy and the fetus.
- Conditions
- Fetal Macrosomatia, Lipid Metabolism Disorders, Hyperlipidemias
- Trial name
- NCT06463990
- Testing
- TyG index
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Cervical Spasm
Laminaria and Misoprostol Before Operative Hysteroscopy
Laminaria and Misoprostol before Operative Hysteroscopy
- Trial name
- NCT03388827
- Testing
- Laminaria tent, Laminaria plus Misoprostol
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Therapeutic Exercise, Motor Imagery
Mental Practice and Therapeutic Exercise in Young Nulliparous Women
Mental practice (both in isolation and also in combination with real practice) has been shown to improve somatosensory and motor variables but so far no study has taken it into the study of women's health.
- Conditions
- Therapeutic Exercise, Motor Imagery, Action Observation
- Trial name
- NCT06073210
- Testing
- Motor Imagery plus therapeutic exercise, Action observation plus therapeutic exercise
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cardiometabolic Health, Pregnancy Related
Cardiometabolic Health in First Time Pregnancy
Women who experience placental complications (syndromes) during pregnancy, such as pre-eclampsia (high blood pressure and kidney problems), gestational hypertension (high blood pressure during pregnancy) and fetal growth…
- Conditions
- Cardiometabolic Health, Pregnancy Related, Diabetes, Placental; Syndrome, Dysfunction
- Trial name
- POPPY (NCT05856318)
- Where
- 7 sites in United Kingdom
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Sexual Behavior
The Pelvic Floor Muscles Strength and Sexual Function in Primigravid and Non-pregnant Nulliparous
This study has two aims: a) to evaluate the pelvic floor muscles strength in primigravid and non-pregnant nulliparous women and to correlate with their sexual function and b) to compare PFM strength and sexual function between…
- Trial name
- NCT02866292
- Testing
- Pelvic floor muscle and sexual function evaluation
- Where
- Brazil
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Fear of Childbirth
The Effects of Antenatal Education and Counseling on Childbirth Fear of Nulliparous Women
This study investigates the effects of antenatal education and counseling on childbirth preparation and pain management given to nulliparous women during the last trimester on their childbirth fear and childbirth attitudes.
- Trial name
- NCT04173351
- Testing
- Education and Counseling
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Complication of Device Insertion
Comparison of the Difficulty on Insertion of IUD Devices Between Nulliparous and Multiparous Women
In this study the investigators compare the difficulty at insertion of IUD between nulliparous and parous women. The investigators compare the pain reported by the patient to the difficulty reported by the professional that…
- Trial name
- NCT01376947
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Pregnancy
The Effect of a Mindfulness-Based Stress Reduction Program Applied to Nulliparous Pregnant Women
Mindfulness-based stress reduction programs are among the effective methods that can contribute to managing anxiety during pregnancy, strengthening mother-fetus interaction, and supporting psychological well-being.
- Trial name
- NCT07510555
- Testing
- Intervention group (Mindfulness-Based Stress Reduction Program), Control group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amasya University
PROM
Pitocin or Oral Misoprostol for PROM IOL
Premature rupture of membranes (PROM) is a common occurrence of pregnancies at term. A delay from PROM to labor is associated with an increased risk of intrauterine infection and associated maternal and fetal morbidity…
- Trial name
- POM PROM (NCT04028765)
- Testing
- Misoprostol, Oxytocin
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Preterm Delivery, Cervical Length
RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short Cervix
The purpose of this study is to see if giving progesterone medication to pregnant women, who have never delivered a baby after 19 weeks of pregnancy and who have a short cervix, lowers the risk of early delivery and improves the…
- Trial name
- SCAN (NCT00439374)
- Testing
- 17 alpha-hydroxyprogesterone caproate
- Where
- 14 sites in United States
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Normal (no Known Injury) Anal Sphincter Female Anatomy
3-D Endoanal Ultrasound: Normative Anatomy of the Anal Sphincter in Nulliparous Females
The purpose of this research study is to measure the muscles that make up your anal sphincter (muscles that control bowel movements) by using ultrasound.
- Trial name
- NCT01123109
- Testing
- 3-D Endoanal Ultrasound
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Labor Long, Nulliparity
HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor
Aim. To evaluate the efficacy of optimizing hydration during labor in nulliparous women with respect to reducing the duration of dilation and the second stage of labor, lowering the incidence of Cesarean sections and fever, and…
- Conditions
- Labor Long, Nulliparity, Premature Rupture of Membrane, Pregnancy, Prolonged
- Trial name
- HYDRATA (NCT03607929)
- Testing
- optimal, variability
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Perineal Lacerations
A Trial of Bed Versus Stirrups Delivery in Nulliparous Women for Prevention of Perineal Lacerations
The investigators hypothesize that the rate of perineal lacerations in nulliparous women will be reduced by a simple change in common obstetrical delivery practice, i.e., bed delivery versus conventional delivery in obstetrical…
- Trial name
- NCT00895973
- Testing
- Stirrups delivery vs bed delivery
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Contraception
Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD Insertion
the aim of the present study is to compare the safety and efficacy of lidocaine spray versus misoprostol in reducing pain during IUD insertion in adolescents and nulliparous women
- Trial name
- NCT04339049
- Testing
- lidocaine spray, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Cairo University
Preeclampsia
Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women
Primary outcome 1. to identify biological changes in nulliparous women at high risk for preeclampsia defined by combined screening by Fetal Medicine Foundation (FMF) 2.
- Trial name
- PRERISK (NCT06200571)
- Where
- 2 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Pregnancy Induced Hypertension, Preeclampsia and Eclampsia
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension
The target population for our study is healthy nulliparous pregnant women (first pregnancy) between the 12-16 week of pregnancy. If a subject is eligible, written consent will be obtained by person to person contact.
- Conditions
- Pregnancy Induced Hypertension, Preeclampsia and Eclampsia, Gestational Hypertension
- Trial name
- NCT04979793
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pregnancy
Hydration and Rate of Cesarean Delivery Among Nulliparous
The hypothesis of the present study is the hydration of nulliparous women with 250ml/hour vs. 125ml/hrs would decrease the rate of primary cesarean section.
- Trial name
- NCT01944787
- Testing
- Routine, IV Hydration at 250cc hour
- Where
- United States
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Chauhan, Suneet P., M.D.