Clinical trials: Nulliparous
Labor Long, Nulliparity
HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor
Aim. To evaluate the efficacy of optimizing hydration during labor in nulliparous women with respect to reducing the duration of dilation and the second stage of labor, lowering the incidence of Cesarean sections and fever, and…
- Conditions
- Labor Long, Nulliparity, Premature Rupture of Membrane, Pregnancy, Prolonged
- Trial name
- HYDRATA (NCT03607929)
- Testing
- optimal, variability
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Perineal Lacerations
A Trial of Bed Versus Stirrups Delivery in Nulliparous Women for Prevention of Perineal Lacerations
The investigators hypothesize that the rate of perineal lacerations in nulliparous women will be reduced by a simple change in common obstetrical delivery practice, i.e., bed delivery versus conventional delivery in obstetrical…
- Trial name
- NCT00895973
- Testing
- Stirrups delivery vs bed delivery
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Contraception
Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD Insertion
the aim of the present study is to compare the safety and efficacy of lidocaine spray versus misoprostol in reducing pain during IUD insertion in adolescents and nulliparous women
- Trial name
- NCT04339049
- Testing
- lidocaine spray, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Risk Pregnancy
Correlation Between Early Induction of Labor and Cesarean Delivery in Low-risk Nulliparous Women
To elucidate whether induction of labor in primiparas with low-risk pregnancies at 38 + 0 to 40 + 6 gestational weeks will increase the cesarean rate, compared with those receiving labor induction at more than 41+0 gestational…
- Trial name
- NCT04412915
- Testing
- Labor induction
- Where
- Taiwan
- Volunteers
- 2,125 people
- Sponsor
- Far Eastern Memorial Hospital
Preeclampsia
Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women
Primary outcome 1. to identify biological changes in nulliparous women at high risk for preeclampsia defined by combined screening by Fetal Medicine Foundation (FMF) 2.
- Trial name
- PRERISK (NCT06200571)
- Where
- 2 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Pregnancy Induced Hypertension, Preeclampsia and Eclampsia
Role of L-citrulline in Prevention of Pregnancy Associated Hypertension
The target population for our study is healthy nulliparous pregnant women (first pregnancy) between the 12-16 week of pregnancy. If a subject is eligible, written consent will be obtained by person to person contact.
- Conditions
- Pregnancy Induced Hypertension, Preeclampsia and Eclampsia, Gestational Hypertension
- Trial name
- NCT04979793
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pregnancy
Hydration and Rate of Cesarean Delivery Among Nulliparous
The hypothesis of the present study is the hydration of nulliparous women with 250ml/hour vs. 125ml/hrs would decrease the rate of primary cesarean section.
- Trial name
- NCT01944787
- Testing
- Routine, IV Hydration at 250cc hour
- Where
- United States
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Chauhan, Suneet P., M.D.
Labor Onset and Length Abnormalities, Pregnancy Related
LaPPS: Labor Podcast for Patient Satisfaction
Patients will be enrolled at 28w0d-36w0d. Randomized to one of two arms: 1. Labor podcasts - Seven labor podcasts that can be downloaded for any podcast app 2. Usual care
- Trial name
- LaPPS (NCT04933708)
- Testing
- Labor Podcast
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Preeclampsia
Aspirin for Prevention of Preeclampsia in Healthy, Nulliparous Obese and Overweight Pregnant Women
Preeclampsia is a pregnancy-specific syndrome that affects 3 - 5% of pregnancies. It is one of the main causes of maternal, fetal and neonatal morbidity and mortality, resulting in approximately 40,000 maternal deaths worldwide…
- Trial name
- NCT03725891
- Testing
- Aspirin 162 mg, Aspirin 81 mg
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Aswan University Hospital
Nulliparous Patient With Unfavourable Cervix, Undergoing Labor Induction at Term ≥ 39SA
Prediction of Labor Induction Outcome in Nulliparous Women
Labor induction rates are increasing worldwide, yet nulliparous patients remain at high risk of failed induction and intrapartum cesarean delivery as well as prolonged labor which are associated with increased maternal morbidity…
- Trial name
- PREDISS (NCT07637318)
- Testing
- Vaginal sample
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intrauterine Contraception
The Effect of Uterine Size and Posture on Intrauterine Contraception in Nulliparous Women
As intrauterine contraception is an increasingly popular form of contraception the objective of our study is to examine if uterine size or posture affects the insertion or use of intrauterine devices.
- Trial name
- NCT01685164
- Testing
- Evaluation of uterine size and posture with ultrasound, IUD insertion, one year follow-up.
- Where
- Finland
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Prolonged Labor
Prediction of Delivery Mode by Ultrasound-assessed Fetal Position in Nulliparous Women With Prolonged First Stage of Labor.
In the past years, numerous studies have been published on the use of ultrasound during labor, showing this is an effective, accurate and objective tool for the assessment of the fetal head position and station.
- Trial name
- NCT05206409
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Uterine Anteflexion
Prospective Study of the Variation in the Angle of Anteflexion of the Uterus Before and After Micturition in Nulliparous Women With Uterine Anteversion.
A monocentric, prospective, comparative, and descriptive clinical study examining the uterine anteflexion angle before and after bladder emptying in nulliparous women with uterine anteversion.
- Trial name
- FLEXIMIX (NCT06669845)
- Testing
- Ultrasonography, Pelvic
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Nulliparous Women Who Scheduled for Labor Induction
Concurrent Membrane Sweeping With Dinoprostone Versus Dinoprostone in Labor Induction of Nulliparas at Term With an Unfavorable Cervix
To compare concurrent membrane sweeping with dinoprostone versus dinoprostone in labor induction for nulliparas at term with an unfavorable cervix
- Trial name
- NCT01792375
- Testing
- Concurrent membrane sweeping with Dinoprostone, 10mg Dinoprostone vaginal insert
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Seoul National University Hospital
Contraception
Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women
The purpose of this study is to see if inserting misoprostol in the vagina or between your cheek and gum before inserting an Intrauterine Device (IUD) in a woman who has never had a baby makes it easier and less painful.
- Trial name
- MPIIN (NCT00886834)
- Testing
- Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnancy Related
Elective Induction of Labour at Thirty Nine Weeks: a Prospective Observational Study
Adverse events are considered to increase in pregnancies extending beyond 39 weeks. For multiparous patients, especially those with a favourable cervix, it is perhaps easy to justify an elective induction at 39 weeks given the…
- Trial name
- EIOL39 (NCT04597528)
- Testing
- Elective Induction
- Where
- India
- Volunteers
- 315 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Arrest of Dilation in Labor
Oral Misoprostol for Labor Augmentation: A Pilot Study
A phase I, open-label trial to determine a safe dose of oral misoprostol required to augment labor in nulliparous women diagnosed with arrest of dilation.
- Trial name
- NCT00906126
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Texas Southwestern Medical Center
Pregnancy
PIEB-PCEA Versus CEI-PCEA for Labor Analgesia in Nulliparous
Epidural analgesia still have an impact on obstetric outcomes and especially on instrumented delivery rates. To assess the best maintainance regimen of epidural analgesia during labor the investigators plan to include 300…
- Trial name
- PIEB (NCT01856166)
- Testing
- Release analgesia by CADD SMITHS PCEA pump, Release analgesia by CADD SMITHS PIEB pump, Levobupivacaine
- Where
- 4 sites in France
- Volunteers
- 304 people
- Sponsor
- University Hospital, Montpellier