Clinical trials: Numbness
Haemodialysis-induced Symptom
Symptom Management Program for Hemodialysis Patients
Self-management intervention may decrease symptom burden and improve functioning over time.
- Trial name
- NCT01620580
- Testing
- Self-management, Dietary Information
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Neuropathy;Peripheral, Thermal Hypesthesia
Effect of Topical Lidocaine on Warm and Cold Sensation in Healthy Individuals
The purpose of the present study is to systematically test the occurrence of paradoxical and illusory responses to cold and warm stimuli in healthy volunteers with artificial sensory loss.
- Trial name
- NCT04865185
- Testing
- Xylocaine spray 100mg/ml, Ethanol
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Teeth Staining, Numbness of the Tongue and Soft Tissue
Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine 0.12% \& Chlorhexidine 0.2%
- Conditions
- Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
- Trial name
- NCT07200063
- Testing
- nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Numbness
Lidocaine Versus Bupivacaine in Orthognathic Surgery
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery.
- Conditions
- Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
- Trial name
- NCT06450028
- Testing
- 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Inferior Alveolar Nerve Injury, Neurosensory Disturbance
Comparison of the Results of Biostimulation Treatment of Inferior Alveolar Nerve Injury Using Nd:YAG and Diode Lasers With Different Wavelengths.
Intraoral surgical procedures such as sagittal split osteotomy, dental implant placement, and surgical extraction of third molars are widely performed interventions in oral and maxillofacial surgery.
- Conditions
- Inferior Alveolar Nerve Injury, Neurosensory Disturbance, Paresthesia and Hypoesthesia, Nerve Regeneration
- Trial name
- NCT07416006
- Testing
- Nd:YAG Laser Biostimulation, Diode Laser Biostimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Anesthesia, Local, Anesthesia, Dental
Behavior of Children Related to Numbness After Dental Local Anesthesia
In children, behavior management is critical to the success of pediatric dental procedures. Most of the studies on local anesthesia performed in children deal with the question how to avoid or minimize pain during injection.
- Trial name
- NCT00363207
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Soft Tissue Anesthesia (Numbness)
Safety and Efficacy Study of NV-101 in Dental Patients
The purpose of this study was: to determine if NV-101 accelerates recovery from numbness compared to placebo to evaluate safety of NV-101
- Trial name
- NCT00154167
- Testing
- NV-101 (phentolamine mesylate solution)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Novalar Pharmaceuticals, Inc.
Ocular GVHD
The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients
The Investigators hypothesize that the recalcitrant nature of ocular GVHD may be related to corneal nerve damage and corneal hypoesthesia.
- Trial name
- NCT04700657
- Testing
- corneal sensation test
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Painful Diabetic Neuropathy
Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression
The UT Southwestern Medical Center at Dallas would like to give you information about a research study that is being done for patients with painful diabetic neuropathy and have not responded to medical treatment.
- Trial name
- DNND (NCT00703209)
- Testing
- Nerve Decompression
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Symptomatic Cervical Disc Disease
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease…
- Trial name
- SMART (NCT04012996)
- Testing
- prodisc C SK and/or Vivo, Mobi-C Cervical Disc
- Where
- 30 sites in United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Centinel Spine
Carpal Tunnel Syndrome
Avazzia HVPC Bio-Electrical Stimulation Technology (BEST™) Microcurrent CTS RCT
A clinical study at Activated Family Chiropractic \& Wellness, is being proposed to test the efficacy of a novel electrical stimulation platform named the Pro-Sport Ultra® designed by AVAZZIA to relieve pain and improve mobility…
- Trial name
- NCT04271319
- Testing
- BEST™ HVPC microcurrent electrical stimulation PRO-SPORT Ultra® Device
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Avazzia, Inc
Healthy
Ultrasound Guided Local Anesthetic Block: Thoracolumbar Interfascial Plane
The purpose of the study is to determine the effectiveness of a new approach to numbing (anesthetizing) nerves in the back and to measure how far the area of anesthesia extends on the skin of the back.
- Trial name
- TLIP (NCT02297191)
- Testing
- Thoracolumbar Interfascial Plane Block, Ropivicaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healthy, Cyclists
Effects of Contemporary Cycling Saddle Designs on Penile Transcutaneus Oxygen and Carbon Dioxide Levels in Elite Road Cyclists Riding on a Stationary Trainer
Aim of this research is to compare novel 3D printed cycling saddle with the bestselling saddles from two major cycling manufacturers in terms of effects on penile blood gasses and update these findings on current style of racing…
- Conditions
- Healthy, Cyclists, Blood Gas Monitoring, Transcutaneous, Penile Numbness
- Trial name
- EC-SADDLE (NCT05887193)
- Testing
- Biothesiometry, Transcutaneous blood gas monitoring, Cycling on a home trainer
- Where
- Czechia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Milan Martínek
Cybersickness, Reduced Sensation
Cybersickness in Different Multisensory Conditions in Virtual Reality
Cybersickness (CS) is characterized as a type of visually induced motion sickness, similar to traditional motion sickness, with specific clinical presentations such as dizziness, eyestrain, oculomotor disorders, blurred vision…
- Trial name
- NCT05534880
- Testing
- Binaural beats
- Where
- 2 sites in Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Piaui
Hypoesthesia
Multimodal Haptic Feedback for Plantar Sensory Substitution
The study will explore the use of a haptic device for sensory substitution in individuals with a movement disorder that has caused loss of plantar sensation. The haptic device consists of two components.
- Trial name
- NCT06232512
- Testing
- Haptic Device
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Carpal Tunnel Syndrome
Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome
This study applies the regenerative properties of autologous fat transfer to treat mild to moderate carpal tunnel syndrome in comparison to the current standard of care, corticosteroid treatment.
- Trial name
- NCT03722303
- Testing
- Fat Injection, Steroid Injection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Carpal Tunnel Syndrome, Susceptibility to
Non-surgical Intervention for Carpal Tunnel Syndrome
This randomized controlled trial graduate student research study will explore the effect of non-surgical intervention of the dorsal application of Kinesio Tape for carpal tunnel syndrome, and forearm wrist hand pain.
- Trial name
- NCT03360344
- Testing
- Kinesio 12 inch Tape, Kinesio 4 inch Tape, Cock up Splint and Lumbrical exercises
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Dry Eye
The THINK Study Incidence of Neurotrophic Keratopathy)
The study purpose is to evaluate corneal sensitivity in patients that have Stage 1 Neurotrphic Keratopathy (NK). Identifying patients with Stage 1 NK, may predict those who will in the future require rhNGF for optimal visual…
- Trial name
- THINK (NCT06482164)
- Testing
- Dry Eye Disease
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC