Clinical trials: Nutrition Disorders in Old Age
Obesity
Weight Loss and Exercise in Obese, Physically Limited, Older Women and Men
The purpose of this study is to determine the effect of weight loss and exercise on physical function, body fat and muscle mass, bone strength, and quality of life.
- Trial name
- NCT00146107
- Testing
- Diet, Exercise, Weight Loss and Exercise
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Washington University School of Medicine
Malnutrition
The Nutritional Health for the Elderly Reference Centre Study (The NHERC Study)
The prevalence of malnutrition among the elderly in Asia is high. The objective of this randomized, parallel, placebo controlled, double-blind study is to evaluate the effects of consuming an adult ONS plus dietary counseling…
- Trial name
- NHERC (NCT03245047)
- Testing
- Oral Nutritional Supplement with AN 777, Oral Nutritional Supplement
- Where
- 4 sites in Singapore
- Volunteers
- 811 people
- Sponsor
- Abbott Nutrition
Obesity, Healthy Lifestyle
Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects
All participants will undergo baseline biopsies of subcutaneous abdominal adipose tissue for cellular/molecular profiling via snRNA-seq and metabolic/physiological assessments (insulin sensitivity, glucose tolerance, and β-cell…
- Trial name
- NCT05653258
- Testing
- Lifestyle Intervention, Dasatinib 100 MG, Quercetin 1000mg
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Obesity, Frailty
Weight Loss and Exercise in Physically Limited Obese Elderly Subjects
The overall purpose of this research is to determine the effect of weight loss and physical training on quality of life, physical function, metabolism, bone strength, body fat and muscle mass.
- Conditions
- Obesity, Frailty, Elderly
- Trial name
- NCT00146133
- Testing
- diet, exercise
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Washington University School of Medicine
Nutrition Disorders in Old Age
Effects of Dairy- and Berry-based Snacks on Nutritional and Functional Status and Quality of Life in Older People
Malnutrition or its risk is common among older people, especially among those receiving home care services. It impairs the quality of life of the older people and results in significant costs to society.
- Trial name
- MAVIRE1 (NCT03352388)
- Testing
- Dairy- and berry-based snacks
- Where
- Finland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Frailty, Inflammation
Fighting Immunosenescence and Promoting Immunity by a Fasting-mimicking Diet Elderly.
Background: Immunosenescence is an aging-dependent phenomenon underlying age dependent deterioration in the function of the immune system, characterized by a decline in B and T cells with a relative increase in natural killer…
- Conditions
- Frailty, Inflammation, Immune System Disorder
- Trial name
- NCT04928963
- Testing
- Prolon - FMD
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Genova
Old Age; Atrophy
The Effect of a Combined Personalized Nutritional Intervention and a Personalized Graded Activity Functional Training Program on Physical Performance in Hospitalized Older Patients, Compared to Usual Care
This project aims to improve physical performance in older patients, by offering a personalized combined nutritional intervention with a physical activity training program.
- Trial name
- FITFOOD (NCT05413616)
- Testing
- FITFOOD lifestyle intervention
- Where
- Netherlands
- Volunteers
- 136 people
- Sponsor
- Radboud University Medical Center
Aging, Hypertension
Aging, Nitrate, Endothelial Function and Muscle Oxygenation
Aging has been associated with reduced bioavailability of nitric oxide (NO) and endothelial dysfunction. Beetroot consumption, a nitrate-rich food, has been associated with increased NO bioconversion, which may promote beneficial…
- Conditions
- Aging, Hypertension, Dyslipidemia, Abdominal Obesity
- Trial name
- NCT02772900
- Testing
- Beetroot-based nutritional gel
- Volunteers
- 25 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Gastroparesis, Hip Fracture
Gastric Emptying in Elderly With Hip Fracture
The gastric emptying of 400 ml 12.6% carbohydrate rich drink is investigated in elderly women, age 75-100, with acute hip fracture.
- Conditions
- Gastroparesis, Hip Fracture, Mild Insufficient Nutrition
- Trial name
- GASEMPHIP (NCT02753010)
- Testing
- Gastric emptying of carbohydrate-rich beverage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Obesity, Heart Failure
The Metabolic Effects of Empagliflozin in Patients With High Risk of Heart Failure
The aim of this trial is to assess the effect of Empagliflozin on lipid and glucose metabolism as well as volume homeostasis and renal function in elderly and obese patients with increased risk of developing heart failure.
- Trial name
- NCT05042973
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in Denmark
- Volunteers
- 165 people
- Sponsor
- Jacob Moller
Obesity, Aging
Semaglutide Use in Elderly Obese Patients
This is a single-center, prospective, controlled, randomized and open label study to investigate the effect of the semaglutide addition to standard of care weight loss intervention (personalized lifestyle and exercise) in elderly…
- Trial name
- NCT05302596
- Testing
- Semaglutide Pen Injector
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Sarcopenia, Obesity
Citrulline Supplementation Combined With Exercise: Effect on Muscle Function in Elderly People (CITEX Study)
The main objective of this study is to determine if oral supplementation of Citrulline, when combined with HIIT, can produce significant changes in body composition, muscle quality, muscle metabolism and functional capacity in…
- Trial name
- CITEX (NCT02417428)
- Testing
- Citrulline, Exercise, without exercise
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Avitaminosis, Delirium, Dementia, Amnestic, Cognitive Disorders
Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly
Low cobalamin (vitamin B12) levels are frequent in the elderly. Most often they reflect a mild metabolic abnormality without clinical symptoms (subclinical cobalamin deficiency).
- Trial name
- NCT00212147
- Testing
- General anesthesia with nitrous oxide, General anesthesia without nitrous oxide
- Where
- 2 sites in United States
- Volunteers
- 444 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Immunity to Polio Vaccines in Malnourished Infants, Immunity to Polio Vaccines in Non-malnourished Infants
IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi.
Chronic malnutrition is associated with lack of effective gut immunity which is a possible explanation for why we see polio cases among a proportion of children who have received 7 or more doses of OPV.Our proposed idea is to…
- Trial name
- MIPV (NCT01695798)
- Testing
- Injectable polio vaccine and Bivalent oral polio vaccine
- Where
- Pakistan
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Dementia, Agitation
Doll Therapy for Agitated Elderly Dementia People
This study is designed to determine the effect of doll therapy on the levels of agitation, nutrition, and daily living activities in elderly patients with dementia and agitation.
- Trial name
- DT (NCT06578819)
- Testing
- doll therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Lung Cancer, Nutrition, Healthy
The Effect of Nutritional Risk Parameters on Postoperative Pulmonary Complications in Geriatric Thoracic Surgery Cases
Preoperative evaluation of nutritional status in geriatric patients with lung cancer and implementation of these practices in elective patients are very important in terms of reducing postoperative complications and accelerating…
- Conditions
- Lung Cancer, Nutrition, Healthy, Postoperative Complications
- Trial name
- NCT05890820
- Testing
- Preoperative nutritional assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Elderly Patients, Malnutrition
Nutritional Intervention and Outcomes in Elderly After Hip Fracture Surgery
Hip fracture is one of the most frequently occurred injury in the elderly and usually requires surgical treatment. Malnutrition is common in elderly patients with hip fracture and is associated with worse outcomes.
- Conditions
- Elderly Patients, Malnutrition, Hip Fractures, Nutritional Intervention
- Trial name
- NCT04451538
- Testing
- Nutritional intervention group, Control group
- Where
- 3 sites in China
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Obese, Elderly
Effects of Aerobic Exercise on Basic Metabolic Panel Perceived Exertion and Exercise Adherence in Elderly
Participants were randomly assigned to two groups prior to their second visit: the High intensity interval training group A (HIIT) and Low intensity interval training group B (LIIT).
- Trial name
- NCT05865145
- Testing
- Electronic Bicycle Ergometer
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rana Elbanna
Periodontal Diseases, Malnutrition
The Association Between Periodontal Disease and Malnutrition in a Group of Elderly People in Thailand.
This study will be determine the association between periodontitis and malnutrition status in older adult.
- Trial name
- NCT05129826
- Testing
- the association between periodontitis and malnutrition status
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Obesity
Assessments of Dietary Restrictions in Young and Elderly Obese Men : Metabolism Obesity Nutrition Age
The prevalence of obesity is growing in elderly with heavy consequences in term of medical complications and mortality, so that this is nowadays an important public health issue.
- Trial name
- MONA (NCT02161926)
- Testing
- dietary restrictions
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Toulouse