Clinical trials: Nutrition Processes
Cardiopulmonary Bypass, Obesity
Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery
Standard Heparin management, based on total body weight, is not well established for obese patients undergoing cardiac surgery with cardiopulmonary bypass (CPB).
- Trial name
- NCT03302195
- Testing
- Heparin, cardiopulmonary bypass pump flow rate
- Where
- Canada
- Volunteers
- 410 people
- Sponsor
- Laval University
Crohn's Disease, Short Bowel Syndrome
Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn's Disease Patients
Citrulline is an amino acid produced in the intestine and in the liver, but the liver does not contribute significantly to circulating citrulline concentrations.
- Conditions
- Crohn's Disease, Short Bowel Syndrome, Malabsorption Syndromes, Celiac Disease
- Trial name
- NCT00138879
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- St Mark's Hospital Foundation
Vitamin A Deficiency, Maternal Mortality
Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh
The purpose of this trial is to determine whether providing women with a weekly oral supplement of vitamin A, either preformed or as beta-carotene, at a dosage equivalent to a recommended intake from early pregnancy through three…
- Conditions
- Vitamin A Deficiency, Maternal Mortality, Infant Mortality
- Trial name
- NCT00198822
- Testing
- Vitamin A or Beta-Carotene Supplements
- Where
- 3 sites in United States, Bangladesh
- Volunteers
- 59,666 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Hyperuricemia, Insulin Resistance
Tart Cherry Juice and Markers of Inflammation, CVD, and Diabetes
In this study, the investigators recruited at-risk individuals (n=26) who were overweight (25.0-29.9 kg/m2) and obese (> 30.0 kg/m2) and likely to exhibit one or more conditions associated with Metabolic Syndrome (MetS).
- Conditions
- Hyperuricemia, Insulin Resistance, Obesity, CVD
- Trial name
- NCT03636529
- Testing
- Tart cherry juice
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Esophageal Cancer, Nutrition Disorders
Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery
The incidence of oesophagogastric cancer has increased by 400% since the 1970s in Ireland and the United Kingdom. In addition, refinement of perioperative management and the now widespread use of multimodal protocols for patients…
- Conditions
- Esophageal Cancer, Nutrition Disorders, Appetite Disorders, Dumping Syndrome
- Trial name
- EndoGut (NCT03734627)
- Testing
- Octreotide Acetate, Saline Solution, Paracetamol
- Where
- 2 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Bariatric Surgery Candidate, Obesity, Morbid
Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery
Obesity is a complex chronic disease, in which both genetic and environmental factors are involved, that shows a great heterogeneity in the response to different weight loss programs.
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Genetic Predisposition, Metabolic Syndrome
- Trial name
- GENBASU (NCT06226194)
- Where
- Spain
- Volunteers
- 6,966 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Obesity, Child Development
CrescNet - Growth Monitoring Network
CrescNet is a network of primary care physicians and pediatricians (n=219) and endocrinological treatment centers (n=33), established in Leipzig in 1998, whose aim is to improve the early detection of growth disorders.
- Conditions
- Obesity, Child Development, Growth Disorders
- Trial name
- CrescNet (NCT03072537)
- Where
- Germany
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Hemodialysis, Probiotics
Effect of Probiotic and Synbiotic Administration on Nutritional Status in Hemodialysis Patients
This study aims to investigate the impact of probiotics and synbiotics on the nutritional status of patients with end-stage kidney disease (ESRD) who are undergoing hemodialysis.
- Conditions
- Hemodialysis, Probiotics, Synbiotics, Nutritional Status
- Trial name
- ProSyn-HD (NCT06891105)
- Testing
- Lactogemikan (Probiotic Supplement), Lactogemikan + Prebiotic Fiber (Synbiotic Supplement)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Premature Birth, Premature Infant
Growing Little PEAPODS Study
The goal of this clinical trial is to learn more about how the food and nutrition babies receive while in the Neonatal Intensive Care Unit (NICU) influences their ability to gain weight and fat-free mass, and their future growth…
- Conditions
- Premature Birth, Premature Infant, Premature, Intrauterine Growth Restriction
- Trial name
- NCT06226051
- Testing
- PEAPOD Infant Body Composition measuring device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Wisconsin, Madison
Bariatric Surgery Candidate
Pre-operative Exercise and Nutrition Therapy on Cardio-metabolic Health in Patients Undergoing Bariatric Surgery
Obesity is a major health concern that has been associated with an estimated 2.8 million deaths worldwide each year. The number of individuals considered obese with a Body Mass Index (BMI) above 30 kg/m2 has grown to more than…
- Trial name
- NCT03854981
- Testing
- Exercise, Standard Care
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Ultra-Processed Food Consumption, Obesity Prevention
Sustainable and AI-Enabled Adolescents and Youth-Centred Interventions to Upgrade Food Choices and Promote Healthy, Sustainable Diets
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-supported, context-aware digital nudging intervention designed to reduce ultra-processed food consumption and improve dietary sustainability among…
- Conditions
- Ultra-Processed Food Consumption, Obesity Prevention, Dietary Behaviour, Unhealthy Diet
- Trial name
- STAY-UP (NCT07514312)
- Testing
- Artificial intelligence-supported digital nudging
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease
The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation
Patients suffering chronic hypercapnic respiratory insufficiency (e.g. in chronic obstructive pulmonary disease, obesity hypoventilation syndrome) benefit from home mechanical ventilation.
- Conditions
- Hypoventilation Syndrome, Chronic Obstructive Pulmonary Disease, Obesity Hypoventilation Syndrome, Restrictive Lung Disease
- Trial name
- NCT03506906
- Testing
- Sleep studies under noninvasive ventilation therapy, Routine tests
- Where
- Germany
- Volunteers
- 105 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Skin Health
Nutritional Study of Fish Oil in Skin Quality in Healthy Women
The skin acts as a barrier against the external environment and prevents water loss from the body. Aging is a natural process leading to changes in the skin and fish oil has been shown to prevent inflammation, hyperpigmentation…
- Trial name
- OPTIHUD (NCT05128240)
- Testing
- Ceto 10
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Epax Norway AS
Frail Elderly, Hip Fracture
Effects of Long-term Intensive Home-based Physiotherapy on Older People With an Operated Hip Fracture or Frailty (RCT).
Our objective is to study the effects of 12 months' intensive home-based physiotherapy (physical exercise) with 12 months' follow-up in two groups of older people: 1) those with an operated hip fracture (60+ y), and 2) those with…
- Trial name
- HIPFRA (NCT02305433)
- Testing
- Home-based physiotherapy (physical exercise)
- Where
- Finland
- Volunteers
- 421 people
- Sponsor
- South Karelia, Social and Health Care District
Chronic Kidney Disease
Low-protein Formula Supplements in Chronic Kidney Disease
Prospective randomized contorl study.Comparing clinical outcome between chronic kidney disease who were prescribed 6% low-protein nutrition supplement along with dietatian regular nutrition education and those without oral…
- Trial name
- NCT05318014
- Testing
- Intervention group, Regular nutrition education
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- Taichung Veterans General Hospital
Obesity, Metabolic Syndrome
Rutazyme Lemon Fermented Product Capsules for Metabolic Function in Adults With Obesity
This study evaluates whether a fruit- and vegetable-based fermented product (Rutazyme® lemon fermented product) taken as a capsule can improve metabolic health in adults with obesity.
- Trial name
- NCT07540949
- Testing
- Rutazyme® Lemon Fermented Product Capsule
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan Sport University
Critically Ill
INTENT-Muscle (A Sub-study of INTENT)
The currently recruiting randomised controlled trial "Intensive Nutrition Therapy Compared to Usual Care in Critically Ill Adults" (INTENT, NCT03292237) is the first multi-centre trial to compare an intensive, individualised…
- Trial name
- NCT04896515
- Testing
- Supplemental parenteral nutrition
- Where
- 6 sites in Australia, New Zealand
- Volunteers
- 21 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Critical Illness, Children
Early Versus Late Parenteral Nutrition in the Pediatric Intensive Care Unit
In the PEPaNIC trial it is investigated whether withholding parenteral nutrition during the first week in critically ill children is beneficial, compared to the current standard of the early start of parenteral nutrition.
- Trial name
- PEPaNIC (NCT01536275)
- Testing
- Late parenteral nutrition
- Where
- 3 sites in Belgium, Canada and 1 more
- Volunteers
- 1,440 people
- Sponsor
- KU Leuven
Bariatric Surgery, Chronic Kidney Diseases
Bariatric Surgery and Chronic Renal Disease
Obesity can be a major driver for the development of chronic kidney disease (CKD), which is a leading cause of death and significant loss in quality of life.
- Conditions
- Bariatric Surgery, Chronic Kidney Diseases, Obesity
- Trial name
- BARICADE (NCT05240443)
- Testing
- Bariatric Surgery + Medical Management of CKD., Medical Management for CKD
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Hyperglycemia, Postprandial, Overweight and Obesity
Ketone Supplementation, Glucose Control, and Cardiovascular Function
Post-prandial hyperglycemic excursions induce a cascade of deleterious effects on the body, including increased inflammation, production of reactive oxygen species, and impaired cardiovascular function.
- Conditions
- Hyperglycemia, Postprandial, Overweight and Obesity, Diabetes Mellitus Risk
- Trial name
- NCT03817749
- Testing
- Exogenous ketone monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
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