Clinical trials: Nutrition Sciences
Wound Surgical, Diabetes
Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty
This study is a single-center, prospective, randomized, open-label clinical trial evaluating three commercially available closed-incision negative pressure wound therapy (ciNPWT) devices: NPseal, PICO, and Prevena, in adult…
- Conditions
- Wound Surgical, Diabetes, Obesity, Chronic Kidney Diseases
- Trial name
- NCT07770633
- Testing
- NP Seal, PICO, Prevena
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Obesity
Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial
The purpose of this study is to develop an evidence-based precision medicine approach for obesity that enhances weight loss and promotes weight loss maintenance.
- Trial name
- NCT06770049
- Testing
- Standard Lifestyle Intervention (SLI) program, Phenotype-tailored Lifestyle Intervention (PLI) program
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Mayo Clinic
Obesity
Engaging Men From Blue-collar Industries in Weight Loss
Objectives*: Primary Objective: Aim 1: Examine the acceptability of tailored behavioral weight loss program and a standard program in men working in blue-collar occupations.
- Trial name
- NCT05386238
- Testing
- Standard behavioral weight loss program, Tailored behavioral weight loss program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Diseases
Inspire HER: Inspiring the Heart and Emotions for Radical Health
Poor heart health puts Black women at risk for a shorter life with more illness than people of any other non-indigenous racial group.
- Conditions
- Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Diseases, Hypertension, Diabetes
- Trial name
- NCT06966258
- Testing
- Inspire HER Intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Childhood Obesity
Abriendo Caminos 2: Clearing the Path to Hispanic Health
Obesity is significantly higher in specific ethnic groups and, in particular, Hispanics. There is an urgent need to implement culturally-sensitive lifestyle interventions and educational programs to decrease the burden of obesity…
- Conditions
- Obesity, Childhood Obesity, Nutrient; Excess, Community Health Education
- Trial name
- NCT03505658
- Testing
- Education and Behavior
- Where
- 5 sites in United States, Puerto Rico
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Obesity
Pilot Study of Laparoscopic Gastric Plication in Adolescents With Severe Obesity
The proposed study aims to investigate the effects of laparoscopic gastric plication (LGP) on excess body weight, body mass index, and weight-related medical and psychological co-morbidities in obese adolescents.
- Trial name
- NCT01980758
- Testing
- Laparoscopic Gastric Plication
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
Hepatic Steatosis, NAFLD
Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study)
Participants 13-18 years of age with extra fat stored in the liver will be randomly assigned to a protein supplement or placebo "fake supplement" for 2 months to see if the participants who get the protein supplement have less…
- Conditions
- Hepatic Steatosis, NAFLD, Adolescent Obesity
- Trial name
- AMINOS (NCT05935826)
- Testing
- Essential Amino Acid Supplement by Amino Co
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Colorado, Denver
Adult Women, Overweight
Effects of Flaxseed Flour in Appetite Sensations, Lipid Profile and Pressure Levels Among Overweighed and Obese Women
Inclusion of foods rich in fiber, such as flaxseed, is a nutritional strategy for treating obesity. The hypothesis of this study is to compare the effects of three types of flaxseed flour - whole brown flaxseed flour, brown…
- Conditions
- Adult Women, Overweight, Obese
- Trial name
- NCT01549626
- Testing
- Defatted flaxseed flour, Golden flaxseed flour, Whole brown flaxseed flour
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Cancer
Complications in Adults With Cancer Receiving an Artificial Parenteral Nutrition in the Central Vein
This observational study will evaluate the frequency of complications in adult cancer patients with central venous parenteral nutrition and the identification of aggravating factors.
- Trial name
- ONAC (NCT04479878)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Local Glucose Uptake, Glucose Metabolism Disorders
Unloading Induced Effects on Local Glucose Uptake Into m. Soleus
The present study aimed to investigate whether a daily intake of lupin protein and a neuromuscular electrical stimulation training twice a day can improve local glucose uptake into m.
- Trial name
- NutriHEP (NCT02698878)
- Testing
- lupin protein, Neuromuscular electrical stimulation, HEPHAISTOS unloading orthotic device
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Obesity
Modifying Diet to Improve Gut Microbiome
The investigators will conduct a 2-arm randomized controlled pilot, feasibility feeding study in which 28 participants will be randomized to receive either a calorie-restricted Dietary Approaches to Stop Hypertension (DASH) diet…
- Trial name
- NCT03924778
- Testing
- DASH diet, standard American diet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Obesity
ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss
The purpose of this clinical research trial is to study safety and effectiveness of the TransPyloric Shuttle System (TPSS) for weight reduction in patients who are considered medically obese.
- Trial name
- NCT02518685
- Testing
- TransPyloric Shuttle, Lifestyle Counseling
- Where
- 9 sites in United States
- Volunteers
- 302 people
- Sponsor
- BaroNova, Inc.
Infant Nutrition
Effect of Feeding Mode on Infant Growth and Cognitive Function
This study is intended to compare growth, nutritional status, and brain development in children fed an Investigational cow's milk based formula containing a nutrient-rich whey protein, a standard cow's milk based formula, or fed…
- Trial name
- NCT02626143
- Testing
- Investigational nutrient-rich whey protein formula, Cow's milk based formula
- Where
- Chile
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
X-linked Hypophosphatemia
Dental Implants in Patients With X-linked Hypophosphatemia
X-linked hypophosphatemia (XLH) is a rare genetic skeletal disease where increased phosphate wasting in the kidney leads to hypophosphatemia and prevents normal mineralization of bone and dentin, with osteomalacia as a principal…
- Trial name
- IMPLANTS-XLH (NCT03879915)
- Testing
- Dental Implant placement
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Illness
A Trial of Enteral Colostrum on Intestinal Permeability in Critically Ill Patients
The effects of colostrum on intestinal permeability in critical ill patients has not been investigated. In current trial, intensive care unit patients with enteral feeding will receive either enteral colostrum or maltodextrin as…
- Trial name
- NCT03186716
- Testing
- Colostrum, Maltodextrin
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- National Nutrition and Food Technology Institute
Nutritional Status of Chinese Inpatients;Nutritional Service Capacity of Medical Institutions in China
China Nutrition Fundamental Data 2020
Malnutrition caused by reduced food intake or assimilation and varying degrees of acute or chronic inflammation is a serious and underappreciated risk factor for adverse clinical outcomes.
- Trial name
- CNFD 2020 (NCT05694104)
- Testing
- Malnutrition
- Where
- China
- Volunteers
- 54,677 people
- Sponsor
- Peking Union Medical College Hospital
Energy Metabolism, Nutrition, Healthy
Technologies and Systems for Assessing Human Energy Metabolism and Nutritional Rehabilitation
The objective of this observational study is to integrate the doubly labeled water (DLW) database from healthy individuals with multimodal data-including, but not limited to, weight, height, age, sex, race, elevation-from cohorts…
- Trial name
- NCT07056504
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Obesity
"Program "Cerdanya on Fitness" to Improve the Lifestyle of People With Obesity in Cerdanya (CF).
To evaluate the effectiveness of an intervention program called "Cerdanya on fitness" based on the prescription of physical activity, healthy nutritional habits and the promotion of positive mental health, adapted to people with…
- Trial name
- CF (NCT05420116)
- Testing
- Cerdanya on Fitness
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Obesity
Environmental Health Effects on Your Physiology
This study evaluates the associations between exposure to air pollutants, green space, and the gut microbiome and metabolome.
- Trial name
- HYPHY (NCT03986814)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Colorado, Boulder
Obesity
Evaluation of the Effect of Body Weight and Composition on Iron Absorption and Blood Volume
A total of 75 subjects will be recruited for this study (25 normal weight, 25 overweight, 25 obese). In each subject blood volume will be determined using the minimally invasive carbon monoxide-rebreathing method (substudy 1) and…
- Trial name
- NCT01884506
- Testing
- labeled iron solution, labeled iron solution and ascorbic acid
- Where
- Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
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