Clinical trials: Nutrition Sciences
Cancer Colorectal, Cancer Cervix
Building Connections
Building Connections seeks to address health and healthcare inequities in socially vulnerable communities. The project will be conducted in collaboration with clinical practices across Massachusetts, serving a diverse population…
- Conditions
- Cancer Colorectal, Cancer Cervix, Depression, Anxiety, Obesity
- Trial name
- NCT07091032
- Testing
- Treatment as Usual, Building Connections Intervention
- Where
- United States
- Volunteers
- 3,600 people
- Sponsor
- Massachusetts General Hospital
Cachexia; Cancer, Muscle Wasting
Muscle Wasting in Children and Adolescents With Cancer
The series of the 3-year study aims to explore parents' experience of caring for a child's weight change among parents of children and adolescents with cancer, examine the associations and trends among muscle wasting and…
- Conditions
- Cachexia; Cancer, Muscle Wasting, Child Development, Adolescent Development
- Trial name
- NCT04353063
- Testing
- Multidisciplinary care with a personalized care
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- National Taiwan University Hospital
Prader-Willi Syndrome
Follow-up of Prader Willi Syndrome Infants Treated by Oxytocin and Comparison With Not-treated Infants.
The objective of this study is to collect data on tolerance and effects of early treatment with oxytocin in children with Prader Willi Syndrome aged from 3 to 4 years and to compare these infants with not treated age-matched…
- Trial name
- OT2SUITE (NCT03081832)
- Testing
- Oxytocin, Control
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Toulouse
Overweight or Obesity
The Effect of AMG 133 on Gastric Emptying
The primary objective of the trial is to evaluate the effect of AMG 133 versus placebo on acetaminophen pharmacokinetics (PK), a marker for gastric emptying, in participants living with overweight or obesity.
- Trial name
- NCT07429032
- Testing
- AMG 133, Acetaminophen
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Amgen
Obesity
Mentors in Motion: A Physical Activity Intervention for Obese Adolescents
Assesing the impact of mentoring on the lifestyle choices of adolescents who are overweight
- Trial name
- MIM (NCT00475163)
- Testing
- Behavior modification
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Obesity
Comparison of Supervised and Unsupervised Physical Activity Programs During a Weight Loss Intervention for Adults
Adults who are overweight or obese are typically prescribed a calorie-restricted diet and physical activity to promote weight loss and improve health.
- Trial name
- REACH (NCT02693132)
- Testing
- Supervised (SUP-PA), Unsupervised (UNSUP-PA), Step-based (STEP)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Type 2
Exercise Timing and the Circadian Clock in Individuals With Type 2 Diabetes and Those at Risk
Many investigations have been done to determine the exercise that can elicit the greatest benefits on glycemic control and metabolic health, with findings suggesting that incorporation of higher intensity and longer duration of…
- Trial name
- EX-TIMING (NCT06136013)
- Testing
- HIIT
- Where
- Portugal
- Volunteers
- 34 people
- Sponsor
- Faculdade de Motricidade Humana
NAFLD, Obesity
Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters.
The study in question is an interventional study with nutritional intervention. The aim of the study is to evaluate whether the adoption of two different models of Mediterranean Diet, based on the different percentage of…
- Conditions
- NAFLD, Obesity, IBS
- Trial name
- NAFLD-POS5 (NCT06275906)
- Testing
- Mediterranean diet and moderate intensity physical exercise (outdoor walking).
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Obesity
MIND Diet Intervention and Cognitive Performance
This single-center, randomized trial examined the effect of MIND diet intervention on cognition and brain structure changes of healthy obese women over three months.
- Trial name
- MIND (NCT04383704)
- Testing
- New Dietary pattern ( Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND))
- Where
- Iran
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Healthy
Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin (JNJ-28431754) in Otherwise Healthy Obese Volunteers
The purpose of this study is to assess the pharmacokinetics (ie, how the body affects the drug) and pharmacodynamics (ie, how the drug affects the body) of increasing doses of canagliflozin (JNJ-28431754) in healthy obese…
- Trial name
- NCT01756404
- Testing
- Canagliflozin (JNJ-28431754)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Fetal Macrosomia, Gestational Diabetes
Regulation Of Maternal Fuel Supply And Neonatal Adiposity
The purpose of this study is to determine whether unrecognized maternal hyperglycemia and postprandial lipemia early or late in gestation predicts excess neonatal adiposity.
- Trial name
- NCT00826904
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
OBESITY, INFLAMMATION
Healthy Effects of an Innovative Probiotic Pasta
The aim of the project was the evaluation of the antioxidant and anti-inflammatory effects of a whole grain pasta, enriched in barley β-glucans and fortified with strains of Bacillus coagulans, versus a control wheat pasta on…
- Conditions
- OBESITY, INFLAMMATION, DYSLIPIDEMIA, CONSTIPATION
- Trial name
- SFLABPASTA (NCT02236533)
- Testing
- whole grain pasta
- Where
- 2 sites in Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Parma
Obesity Morbid, Obesity-Associated Insulin Resistance
Role NLRP3 Inflammasome in Weight Loss Following Sleeve Gastrectomy in Morbidly Obese Patients
Epidemiological studies show a very rapid increase in the epidemic of obesity in the Caribbean population. 6 out of 10 adults are overweight and 1 out of 4 is obese. Most are women.
- Trial name
- BARIAMITRI (NCT04814147)
- Testing
- Sleeve gastrectomy
- Where
- Martinique
- Volunteers
- 20 people
- Sponsor
- University Hospital Center of Martinique
Morbid Obesity
Laparoscopic Adjustable Gastric Banding Versus Laparoscopic Sleeve Gastrectomy
The investigators aim to determine the clinical and metabolic outcomes of two available bariatric restrictive procedures: laparoscopic adjustable gastric banding (LAP-BAND) and laparoscopic sleeve gastrectomy for the treatment of…
- Trial name
- NCT00434655
- Testing
- Laparoscopic restrictive procedure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- North Texas Veterans Healthcare System
Prediabetes, Brain Insulin Sensitivity
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals
Primary aim of the study is to assess the effect of 12-week daily avocado consumption on cerebral blood flow and markers of cardio- and vascular health in both, the periphery and the brain, in pre-diabetic individuals with…
- Conditions
- Prediabetes, Brain Insulin Sensitivity, Cerebral Blood Flow, Satiety and Food Intake
- Trial name
- NCT07752225
- Testing
- Avocados
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht University Medical Center
Overweight, Obesity
Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy Range
This study will look how well semaglutide tablets taken once daily helps people with body weight above the healthy range. Participants will either get semaglutide 25 milligram (mg) once daily or placebo once daily.
- Trial name
- OASIS 4 (NCT05564117)
- Testing
- Semaglutide
- Where
- 23 sites in United States, Canada and 2 more
- Volunteers
- 307 people
- Sponsor
- Novo Nordisk A/S
Mediterranean Diet, Overweight or Obese Adults
ENERGY2MOB STUDY: OBESITY MANAGEMENT IN BERGUEDÀ
Background: Obesity is a prevalent multifactorial disease worldwide and has become a significant public health concern. The latest data from the 2022 Catalonia Health Survey show that 56.2% of men and 43.7% of women are…
- Conditions
- Mediterranean Diet, Overweight or Obese Adults, Exercise Therapy, Cardiovascular Diseases
- Trial name
- ENERGY2MOB (NCT06988904)
- Testing
- Energy2MOB
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cancer, Nutrition Related Cancer
Study to Evaluate the Organoleptic Perception of Oral Nutritional Supplements for Oncological Patients
Nutritional therapy is key to helping cancer patients get the nutrients they need to maintain body weight, strength, tissue and organ integrity, and face likely infections.
- Conditions
- Cancer, Nutrition Related Cancer, Malnutrition
- Trial name
- SENSORIAL (NCT05488184)
- Testing
- Flavoured Oral Nutritional Supplement (ONS)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Obesity and Overweight
Effects of Antagonizing the Ghrelin Receptor on Brain Food Cue Reactivity in Obesity
The naturally occurring peptide hormone liver-expressed antimicrobial peptide 2 (LEAP2) in an antagonist/inverse agonist towards the ghrelin receptor.
- Trial name
- LEAP2fMRI (NCT06845033)
- Testing
- LEAP2 infusion
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Infertility, Female, Vitamin D Deficiency
Vitamin D Status Among Infertile Women in Sweden
The goal of this prospective cohort study is to learn about the overall and seasonal prevalence of vitamin D insufficiency and its determinants in a population of women with infertility who will go through in vitro fertilization…
- Trial name
- NCT05848349
- Where
- Sweden
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
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