Clinical trials: Nutrition Therapy
Nasopharyngeal Carcinoma, Nutritional Support
Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma
Concurrent chemoradiotherapy(CCRT) is the principal treatment for nasopharyngeal carcinoma(NPC). Studies have shown that malnutrition is very common in patients with NPC after chemoradiotherapy.
- Trial name
- NCT04823468
- Testing
- Abbott®Ensure, Intensity Modulated Radiation Therapy, cisplatin
- Where
- 13 sites in China
- Volunteers
- 236 people
- Sponsor
- Jinsheng Hong
Helicobacter Pylori Infection, Obesity, Morbid
THE EFFECT OF HELICOBACTER PYLORI ERADICATION THERAPY TO GASTRIC WALL THICKNESS BEFORE THE LAPAROSCOPIC SLEEVE GASTRECTOMY
Laparoscopic sleeve gastrectomy is one of the most popular bariatric surgery in the world. The most important complication about this surgery that the leakage from the stapler line because of the inconvenient stapler choice..The…
- Trial name
- NCT03757650
- Testing
- Bismuth Subsalicylate
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Obesity
Long-limb or Distal Gastric Bypass for Superobesity - Randomized Study
The main study objective: To evaluate long-limb gastric bypass (150 cm alimentary limb) vs. "distal" gastric bypass (common channel 150 cm) in the treatment of superobesity (BMI 50-60 kg/m2).
- Trial name
- NCT00821197
- Testing
- long-limb gastric bypass, distal gastric bypass
- Where
- Norway
- Volunteers
- 115 people
- Sponsor
- Oslo University Hospital
Malnutrition
Effect of Continued Nutritional Support at Hospital Discharge on Mortality, Frailty, Functional Outcomes and Recovery
This study is to compare the sustained post-discharge nutritional support to reach individual energy and protein goals to usual care home nutrition in medical patients at nutritional risk.
- Trial name
- EFFORT II (NCT04926597)
- Testing
- nutritional supplement, individualized nutritional guidelines, general nutritional information
- Where
- 18 sites in Spain, Switzerland
- Volunteers
- 1,200 people
- Sponsor
- Philipp Schuetz
Malnourished Children, Stunting of Growth
Comprehensive Nutritional Support for Children in Zambia (ZamCNC) - A Pilot Investigation
In a recently completed intervention study, more than 50% of children in Lusaka were found to be stunted by age two, even when nutritional supplements were provided.
- Trial name
- ZamCnC (NCT07153913)
- Testing
- Intensive growth support
- Where
- Zambia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Günther Fink
PreDiabetes, Obesity, Morbid
Effectiveness of Dapagliflozin for Weight Loss
Mexico has one of the highest prevalence of obesity, reported on 32.4 percent of people over 20 years old, with a prevalence of obesity class III of 1.8 percent on males and 4.1 percent on females.
- Conditions
- PreDiabetes, Obesity, Morbid, Diabetes Mellitus, Type 2
- Trial name
- NCT03968224
- Testing
- Dapagliflozin/Metformin, Metformin
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Centro Medico Nacional Siglo XXI IMSS
Overweight and Obesity
Teaching Obesity Treatment Options to Adult Learners Intervention Via VA Video Connect
The goal of this study is to assess the feasibility and acceptability of Teaching Obesity Treatment Options to Adult Learners (TOTAL intervention), which includes an educational video about obesity treatment options within VA in…
- Trial name
- TOTAL (NCT04878289)
- Testing
- TOTAL with Motivational Telemedicine Sessions
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Wisconsin, Madison
Esophagectomy, Pancreaticoduodenectomy
Preoperative Nutritional Support in Esophagectomy or Pancreaticoduodenectomy
We are proposing to evaluate the benefit of preoperative nutritional support with Impact Advanced Recovery in the most vulnerable group of elective gastrointestinal surgery patients who may experience a complication, esophagus…
- Trial name
- NCT00585624
- Testing
- Impact Advanced Recovery, No supplement
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Wisconsin, Madison
Obesity, Diabetes Mellitus, Type 2
A Study of the Efficacy and Safety of Topiramate in the Treatment fo Obese, Type 2 Diabetic Patients Treated With Metformin
The purpose of this study is to compare the efficacy (in terms of weight and hemoglobin type A1c [HbA1c]) and safety of topiramate (96 milligrams[mg] or 192 mg daily) with placebo in the treatment of obesity in Type 2 diabetic…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset
- Trial name
- NCT00231660
- Testing
- topiramate
- Volunteers
- 211 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Esophageal Cancer, Nutrition Aspect of Cancer
Nutritional Support During Induction Therapy for Esophageal Cancer
Patients diagnosed with esophageal cancer have difficulty eating, as the food pipe becomes obstructed by the cancer. This may impair the ability for the patient to receive appropriate calorie intake, especially during…
- Trial name
- NCT05314946
- Testing
- No feeding tube placed, Placement of a percutaneous feeding tube
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Mehdi Qiabi
Amyotrophic Lateral Sclerosis, Gastrointestinal Intolerance
Oral Intake of Enteral Nutrition Formula Preceding Placement and Feeding Via GTube and Its Impact on Formula Intolerance in pALS
The main objective of the proposed study is to evaluate if oral intake of EN formula preceding Gtube placement will impact tolerance upon placement and feeding via Gtube in pALS.
- Conditions
- Amyotrophic Lateral Sclerosis, Gastrointestinal Intolerance, Enteral Nutrition Therapy
- Trial name
- NCT06609213
- Testing
- Medical Food
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Andrea Charvet
Obesity, Weight Loss
Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
The purpose of this registry study is to collect data through medical chart review and in patient visits on the efficacy and safety of various Endoscopic Bariatric therapies (EBTs).
- Conditions
- Obesity, Weight Loss, Gastro Esophageal Reflux, Bariatric Surgery Candidate
- Trial name
- EBT (NCT04494048)
- Testing
- Endoscopic Bariatric Therapies
- Where
- United States
- Volunteers
- 9,999 people
- Sponsor
- Weill Medical College of Cornell University
Obesity
Evaluation of Orlistat as Adjuvant Treatment of Obesity in Adults
The purpose of this study is to evaluate efficacy of orlistat 60 mg as adjuvant treatment of Obesity in adults.
- Trial name
- NCT01755676
- Testing
- Orlistat 60 mg
- Where
- 5 sites in Brazil
- Volunteers
- 638 people
- Sponsor
- EMS
Obesity, Morbid, Bariatric Surgery
Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds
The goal of this pilot study is to establish the feasibility and initial efficacy of the combination of phentermine and topiramate for adolescents and young adults who require additional risk reduction after bariatric surgery.
- Conditions
- Obesity, Morbid, Bariatric Surgery, Adolescent, Young Adult
- Trial name
- NCT04095104
- Testing
- Phentermine, Immediate Release Topiramate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver
Cancer-related Fatigue, Neoplasms (Cancer / Tumors)
Integrated Chinese and Western Therapy for Cancer-Related Fatigue
Cancer-related fatigue (CRF) is a common and debilitating symptom in patients with cancer. Evidence-based non-pharmacological approaches include sleep hygiene, physical activity, nutritional management, and traditional Chinese…
- Trial name
- NCT07445243
- Testing
- Integrated Chinese and Western Holistic Care Program
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Taichung Tzu Chi Hospital
Obesity/therapy
Rhomboid Intercostal Block with Subserratus Plane Block in Bariatric Surgery
Standard analgesic techniques such as patient-controlled analgesia (PCA) and continuous epidural analgesia (CEA) are effective but associated with considerable side effects, including nausea, hypotension, and respiratory…
- Trial name
- NCT06729515
- Testing
- PCA, CEA, RISS
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xiaguang Duan
Obesity
Weight Loss and Reversing T2D Through eHealth Coaching
Background: Systematic reviews conclude that Internet and mobile interventions can significantly change lifestyle in a short time span.
- Trial name
- LIVA (NCT03788915)
- Testing
- Online dietetic lifestyle counseling, Usual care
- Where
- 2 sites in Denmark
- Volunteers
- 340 people
- Sponsor
- University of Southern Denmark
Obesity & Overweight, Obesity
Genetic, Microbiological and Behavioral Factors in Obesity
This study will assess the impact of genetic markers, microbiological (microbiome) and behavioral factors on tolerance, adherence and effectiveness of dual GLP1/GIP RA in the treatment of obesity.
- Conditions
- Obesity & Overweight, Obesity, Genetics
- Trial name
- OPTIMIZE-GEN (NCT07650149)
- Testing
- genetic polymorphism, gut microbiome
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Jan Kochanowski University
Sleep Apnea, Obstructive, Bariatric Surgery
Effect of CPAP Versus APAP in Patients With Obesity Undergoing Bariatric Surgery Protocol
Introduction Obstructive sleep apnea (OSA) is a common disorder in obese patients, especially those undergoing bariatric surgery.
- Conditions
- Sleep Apnea, Obstructive, Bariatric Surgery, Obesity, Treatment Adherence and Compliance
- Trial name
- ObesAOS (NCT07001215)
- Testing
- In the intervention group, patients will be treated with auto-adjusting APAP, providing variable pressures throughout the sleep hours., CPAP
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Obesity
Internet Obesity Treatment Enhanced With Motivational Interviewing
Internet-based weight control programs have been shown effective in producing weight loss, but in-person delivery of behavioral weight control produces significantly greater weight loss than on-line delivery of the same program.
- Trial name
- iReach2 (NCT01232699)
- Testing
- Internet Obesity Treatment, Internet Obesity Treatment with MI, Contingent MI
- Where
- 2 sites in United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- University of Vermont