Clinical trials: Nutritional Deficiencies
Vitamin D Deficiency, Secondary Hyperparathyroidism
Vitamin D Status in Males in Jerusalem Area and Its Correlation to Parathyroid Hormone (PTH) Level and Bone Mineral Density
Because of its high sun exposure, Israel was traditionally supposed to be protected from vitamin D deficiency, and the country food products hardly contain vitamin D supplements.
- Conditions
- Vitamin D Deficiency, Secondary Hyperparathyroidism, Osteomalacia
- Trial name
- NCT01025128
- Testing
- 25 OH vitamin D
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Child Development, Parenting
The Sugira Muryango PLAY Collaborative
The Research Program on Children and Adversity (RPCA) has successfully grown its evidence-based home-visiting program-Sugira Muryango (SM)-in Rwanda, as policies and programs aligned with the Rwandan social protection system have…
- Conditions
- Child Development, Parenting, Parent-Child Relations, Child Malnutrition
- Trial name
- NCT04257383
- Testing
- Sugira Muryango
- Where
- Rwanda
- Volunteers
- 1,333 people, healthy volunteers welcome
- Sponsor
- Boston College
Burn, Growth
Bone Mineral Density, Body Composition and Growth Following Severe Burn Injury
The purpose of this study is two-fold. The first is to establish that bone mineral density is diminished among children admitted to this regional burn center as compared to healthy non-burned children.
- Conditions
- Burn, Growth, Malnutrition
- Trial name
- NCT00285090
- Testing
- Calcium, Vitamin D, Calcium,Vitamin D, Calcium, VitaminD
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kathy Prelack, PhD, RD
Iron-deficiency
Iron Absorption and Variations of Iron Status, Hepcidin, Inflammation and Sex Hormones During the Menstrual Cycle
Iron supplementation is the first line of treatment of iron deficiency in most women, but we do not know when the best time is to supplement in the context of the menstrual cycle.
- Trial name
- MBL_Abs (NCT05580783)
- Testing
- Test meal labelled with 54Fe, Test meal labelled with 57Fe, Test meal labelled with 58Fe
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Isabelle Herter-Aeberli
Vitamin D Deficiency
Vitamin D and Health Status of British African-Caribbean Women
Vitamin D deficiency remains a global public health issue (Wilson 2017). In the United Kingdom (UK). There is a lack of research looking at vitamin D status of the British African-Caribbean population.
- Trial name
- NCT04179370
- Testing
- N/A - no intervention. Observational study.
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Cerebral Amyloid Angiopathy
Balance Eyesight and Muscle Tension in the Cervical Spine in Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy (CAA) is one form of disease of the small vessels of the brain and can cause frequent cerebral hemorrhages as well as other types of stroke.
- Trial name
- NCT05082194
- Testing
- balance with open and closed eyes
- Where
- Poland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Anna Olczak
Deficiencies Micronutrient, Nutrition Disorders
Effect of Consuming Vitamin A-fortified Sugar on Serum Retinol Levels in Children
The increase in vitamin A deficiency (<20 mcg/dL) among children under five in Colombia (2010-2015) is a public health problem (27.3%).
- Trial name
- NCT07860060
- Testing
- white sugar fortified with retinol, refined white sugar for culinary use
- Where
- Colombia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Rickets
Study to Assess the Use of a Simple Lab Test to Screen for Rickets in Children
Some experts recommend that all breastfed babies receive supplemental vitamin D. The purpose of this study is to determine the rate of vitamin D use in breastfed babies, the recommendations of pediatricians regarding vitamin D…
- Trial name
- NCT00502866
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Iron Deficiency Anemia
Effect of Rice Fortification With Iron on Anemia Among Children
This was a double-blind community-based trial, placebo controlled. During 16 weeks, children in the intervention group (GI, n=180) received iron fortified rice, and children in the control group (GC, n=174) received rice with…
- Trial name
- NCT00727545
- Testing
- iron bisglycine chelate
- Where
- Brazil
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Micronutrient Deficiency
Comparison of Two Nutrition Interventions in Young Children in El Salvador
Adequate nutrition during the first years of life is essential to reach full body and brain development potential. Children under the age of 5 in Central America and El Salvador suffer from micronutrient deficiencies.
- Trial name
- NCT02567981
- Testing
- 21 micronutrient-fortified supplement, Cereal Fortificado (Fortified Cereal), Ferrous sulphate
- Where
- El Salvador
- Volunteers
- 4,577 people, healthy volunteers welcome
- Sponsor
- The Mathile Institute for the Advancement of Human Nutrition
Parkinson´s Disease, REM Sleep Behavior Disorder (iRBD)
The Swedish BioFINDER Sleep Study
BioFINDER-Sleep study was established in 2021 and will include patients with early Parkinson´s disease (PD) and persons with iRBD to provide essential insights into the underlying mechanisms of the progressive neurodegenerative…
- Conditions
- Parkinson´s Disease, REM Sleep Behavior Disorder (iRBD), Lewy Body Disease, Synucleinopathy
- Trial name
- NCT07533799
- Testing
- Dopamine transporter PET scan with [18F]FE-PE2I, Magnetic resonance imaging (MRI), [123I] MIBG scintigraphy of the heart
- Where
- Sweden
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Mitochondrial Diseases, Mitochondrial Respiratory Chain Deficiencies
A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease
This will be a double blind, randomised, placebo controlled, single and multiple oral dose study conducted in 3 parts: Part A, Part B and Part C.
- Conditions
- Mitochondrial Diseases, Mitochondrial Respiratory Chain Deficiencies, MELAS Syndrome, Mitochondrial Myopathies
- Trial name
- NCT03888716
- Testing
- KL1333
- Where
- 2 sites in United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Abliva AB
Vitamin D Deficiency
Environmental & Genetic Influences on Vitamin D Status
The purpose of this study is to determine the effect of environmental and genetic influences on Vitamin D status.
- Trial name
- NCT01208636
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Creighton University
MELAS Syndrome, Mitochondrial Respiratory Chain Deficiencies
Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers
The purpose of this First In Human study is to investigate the safety and tolerability of KL1333 after a single oral dose and to investigate the pharmacokinetic characteristics of KL1333 after a single oral dose.
- Trial name
- NCT03056209
- Testing
- KL1333 25 mg, KL1333 50 mg, KL1333 100 mg
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yungjin Pharm. Co., Ltd.
Malnutrition; Diabetes, Diabetes
Metabolic Characteristics of Lean Diabetes in Rural and Semi-urban India and in the United States
This purpose of this study is to define the metabolic characteristics of individuals with Lean Diabetes. We aim to determine whether differences in body composition, including any differences in lipid (fat) deposition, exist…
- Trial name
- NCT02987335
- Testing
- Pancreatic Clamp
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Amyotrophic Lateral Sclerosis
Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders
The purpose of this study is to collect, from patients with sporadic and familial ALS and their family members, clinical data and blood samples for extraction of DNA, RNA, preparation of lymphocytes, plasma and serum to establish…
- Trial name
- NCT05474235
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Appetite Loss, Physical Inactivity
APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
The APPETITE Trial aims to investigate the efficacy of innovative plant protein fibre (PPF) products (developed in a previous workpackage) as part of a personalised diet with/out physical activity on appetite and incidence of…
- Conditions
- Appetite Loss, Physical Inactivity, Undernutrition, Anorexia of Aging
- Trial name
- NCT05608707
- Testing
- Physical activity intervention, Personalised nutrition intervention
- Where
- 3 sites in Germany, Ireland and 1 more
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Healing Wound, Iron-deficiency
Impact of Iron Stores on Wound Healing in Plastic Surgery
In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight.
- Conditions
- Healing Wound, Iron-deficiency, Surgical Wound
- Trial name
- IRONPLAST (NCT04276168)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Virtual Peer-to-peer Support Programme for Carers of MND
Background/scope There is growing recognition that family caregiving is a serious public health issue requiring supportive interventions.
- Trial name
- NCT04695210
- Testing
- Virtual peer-to-peer support
- Where
- 25 sites in United Kingdom
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- King's College London
Diarrhea, Malnutrition
Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development
Malnutrition is considered one of the most prevalent risk factors for morbidity and mortality in children under five. An estimated 20% of children in the developing world are malnourished [1] and poor nutrition is linked to more…
- Conditions
- Diarrhea, Malnutrition, Stunting, Wasting
- Trial name
- MAL-ED (NCT02441426)
- Where
- 8 sites in Bangladesh, Brazil and 6 more
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health
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