Clinical trials: Nutritional Supplement
Retinal Detachment
Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment
Retinal detachment occurs when fluid separates the retina (a thin, light sensing tissue) from its usual attachment at the back of the eye.
- Trial name
- NOMAD (NCT06587945)
- Testing
- Nicotinamide Riboside, Vitrectomy and Gas tamponade
- Where
- 5 sites in Australia
- Volunteers
- 144 people
- Sponsor
- Center for Eye Research Australia
Low Muscle Strength, Malnutrition
Efficacy of Oral Nutritional Supplement in Community-Dwelling Adults Following Acute Care
The study aims to determine the effects of Oral Nutritional Supplement (ONS) added to usual care on body weight compared with usual care alone in community-dwelling adults aged 55 years and older who are at risk of malnutrition…
- Trial name
- NCT07753239
- Testing
- ONS, Standard of Care (SOC)
- Where
- 7 sites in Thailand
- Volunteers
- 304 people
- Sponsor
- Abbott Nutrition
Metabolic Effects, Immunosuppressive Agents
Impact of SCFA Supplementation on Metabolic Profiles in Serum and Urine of Kidney Transplant Recipients.
This is a randomized, double-blind, placebo-controlled clinical trial evaluating the impact of short-chain fatty acid (SCFA) supplementation on the serum and urinary metabolome in stable kidney transplant recipients.
- Conditions
- Metabolic Effects, Immunosuppressive Agents, Adverse Events, Imunological Effects
- Trial name
- METAKID (NCT06951581)
- Testing
- Short Chain Fatty Acid
- Where
- Slovakia
- Volunteers
- 41 people
- Sponsor
- University Hospital, Martin
Low Birth Weight, Preterm Birth
Animal Source Food Supplement and Pregnancy in Vietnam
The purpose of this study is to determine if a nutrient-rich supplement of animal-source foods ingested 5d/wk from pre-conception to term improves maternal nutrient status, decreases infections, and improves birth weight and…
- Trial name
- VACVINA (NCT01235767)
- Testing
- Food
- Where
- Vietnam
- Volunteers
- 291 people
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Herb-Herb Interaction, Pharmacokinetics
Pharmacokinetics of Kava and Kratom Alone and in Combination
This study is being conducted to evaluate how different formulations of the Feel Free® Tonic containing Kava, Kratom, or a combination of both are processed in the body in healthy adults.
- Trial name
- NCT07583407
- Testing
- Kava and Kratom Herbal Supplement, Kava Herbal Supplement, Kratom Herbal Supplement
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Botanic Tonics, LLC
Health Adult Subjects
Effects of NR Supplementation on Metabolic Flexibility in Zone 2 Training
Zone 2 training, a low-intensity endurance exercise performed at approximately 66-80% of VO₂max or near the first ventilatory threshold, has gained popularity for improving aerobic capacity, fat metabolism, and mitochondrial…
- Trial name
- NCT07344636
- Testing
- Nicotinamide Riboside (NR)
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ZHANG Jiaqi
Muscle Loss
The Effect of Creatine on Muscle Loss
The primary aim of this study is to determine the effect of creatine supplementation on muscle mass loss during short-term immobilisation in healthy, young people.
- Trial name
- CML (NCT01894737)
- Testing
- Creatine supplementation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Infants
Efficacy of a Dietary Supplement in Infants
This is a double-blind, randomized, placebo-controlled nutritional study of healthy term infants. The primary objective of the trial is to demonstrate a favorable change in fecal microbiome composition in infants receiving a…
- Trial name
- NCT07341477
- Testing
- Experimental Group, Control Group (CG)
- Where
- 2 sites in Philippines
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Muscle Injury
Effects of Protein Hydrolysate Supplementation Influencing Strength Recovery and Expression of Muscle Damage Markers Post-exercise
A randomised placebo controlled, double-blind, 30 Volunteer trial of Elio™ administered 2.4 grams per day in assessing its effects on post-exercise strength recovery and increases in markers associated with muscle injury and…
- Trial name
- NCT05159375
- Testing
- Elio, SMCC
- Where
- Ireland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Hypertension
Bariatric Surgery and Cardiovascular Responses to Sodium Nitrate
Inorganic nitrite and nitrate can be reduced to NO and NO-related species such as S-nitrosothiols via the nitrate-nitrite-NO pathway.
- Trial name
- NCT06303830
- Testing
- Sodium nitrate
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Stress, Mood Disturbance
Enhancement of Calmness and Mood Following Acute Lemon Balm Supplementation During Cognitive Demand in Adults
This study aims to investigate the effect of a single dose (300mg) of encapsulated aqueous lemon balm extract on measures of calmness and mood during periods of cognitive demand over the course of the day in healthy adults aged…
- Trial name
- LemCog (NCT06183372)
- Testing
- Lemon balm
- Where
- United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Reading
Dyspepsia, H. Pylori Infection
Supplementation With L. Reuteri in H. Pylori Infected Adults
To determine whether simultaneous use of L. reuteri ProGastria and proton pump inhibitors can eradicate H. pylori in humans in the absence of antibiotics.
- Trial name
- NCT01449500
- Testing
- L. reuteri
- Where
- Slovakia
- Volunteers
- 56 people
- Sponsor
- Lama Medical Care s.r.o.
Hypertension
L-citrulline Supplementation, Cold Exposure, & Post-Exercise Muscle Ischemia
Cardiovascular disease (CVD) continues to be the major cause of morbidity and mortality in western countries. It has been shown that CVD events are known to be higher in the winter than in the summer.
- Trial name
- NCT02104375
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Florida State University
Chronic Low-back Pain
Supplementation With Vitamin D3 on Chronic Low Back Pain Patient
The study was designed as a randomized double-blind placebo-controlled clinical trial with 8-week Vitamin D3 and physical activity intervention.
- Trial name
- NCT06082375
- Testing
- Vitamin D
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Damage Muscle
Spirulina Supplementation In Recovery From Damaging Exercise
Exercise can cause muscle damage, leading to a loss in muscle function, increased muscle soreness and inflammation. Evidence supports the use of nutritional strategies to help recovery. Spirulina is a type of algae.
- Trial name
- SPIRAL (NCT06391957)
- Testing
- Spirulina supplement, Eccentric exercise
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Nutritional Supplement Toxicity
Effect of 1 Year Vitamin D or D Plus B-vitamins on Bone Markers in Elderly People (KnoVIB)
The standard recommendation to prevent osteoporosis is to supplement low doses of vitamin D and calcium. Hyperhomocysteinemia has been related to increased risk of osteoporosis.
- Trial name
- KnoVIB (NCT02586181)
- Testing
- Vitamin D and Calcium, Vitamin D, Calcium, Vitamins B9, B6, B12
- Where
- Germany
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Iron Deficiency, Anaemia in Children
A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial
This study aims to determine whether IHAT is non-inferior to ferrous sulphate at correcting iron deficiency and anaemia, and if IHAT does not increase diarrhoea risk in young children living in rural and resource-poor areas of…
- Trial name
- IHAT-Gut (NCT02941081)
- Testing
- IHAT, Ferrous Sulphate
- Where
- The Gambia
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Nosocomial Infection, Diarrhea, Infantile
Effect and Tolerability of Lactobacillus Rhamnosus GG LA801 for the Preventive Nutritional Care of Nosocomial Diarrhea in Children
One of the most common infections acquired in hospital, also known as nosocomial infections, is intestinal infections. These infections can lead to the development of nosocomial diarrhea which can have serious consequences in…
- Trial name
- EPISODE (NCT04628819)
- Where
- 2 sites in France
- Volunteers
- 61 people
- Sponsor
- PiLeJe
Sickle Cells Disease
Vitamin D and Bisphosphonates in the Treatment of Sickle Cell Disease
Sickle cell disease (SCD) is a worldwide distributed hereditary red cell disorder, which affects approximately 75,000 individuals in the United States and almost 20,000- 25,000 subjects in Europe, this latter mainly related to…
- Trial name
- NCT02972138
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Società Italiana Talassemie ed Emoglobinopatie
Red Blood Cell Disorder, Oxidative Stress
Effect of Krill Oil Supplementation on Red Blood Cell Physiology Against Changes in Markers of Iron Metabolism.
Research group: the research will be conducted in a homogeneous group of professional rowers (N=30), all competitors qualified for the Polish Youth Rowing Team: aged 18 - 24, because the age group must be homogeneous, the size of…
- Conditions
- Red Blood Cell Disorder, Oxidative Stress, Iron Metabolism Disorders
- Trial name
- NCT06151548
- Testing
- THYROX (Atlantic krill oil).
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Poznan University of Physical Education
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