Clinical trials: Nutritional Supplement
Urolithiasis
ButOx Human Trial: An Open Label Prospective Cohort Study to Investigate the Effect of Tributyrin (Butyrate Precursor Molecule) Supplementation on Markers of Calcium Oxalate Nephrolithiasis
Kidney stone disease (KSD) is a condition where there are crystal deposits in the kidney. The gut microbiome is a community of gut bacteria which can produce substances such as short chain fatty acids (SCFAs).
- Trial name
- ButOx (NCT07004257)
- Testing
- tributyrin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Elderly Women, Sarcopenia
Dietary Supplementation With Omega-3 Fatty Acid in Muscle Response
Both aging and other factors associated with it may contribute to the development of sarcopenia, such as lack of physical activity, inadequate food intake, hormonal changes and age-related increases in cytokine levels.
- Trial name
- NCT03462771
- Testing
- Fish oil, sunflower oil
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eduardo Ferriolli
Calcium, Osteopenia
Effects of Amorphous Calcium Carbonate Supplementation on Bone Health in Postmenopausal Women With Osteopenia
This research was designed in accordance to the Method for Efficacy Assessment of Health Food for Bone Heath. Changes to bone density were measured to evaluate the effectiveness of amorphous calcium carbonate in maintaining bone…
- Conditions
- Calcium, Osteopenia, Bone Mineral Density, Bone Turnover Marker
- Trial name
- NCT05810909
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
Phenylketonuria
Low Phenylalanine Diet for Mothers With Phenylketonuria (PKU)
Phenylketonuria (PKU) is a rare genetic condition. If not treated, PKU can cause severe mental retardation. Women with PKU are advised to eat a special diet when pregnant to prevent mental retardation in their children.
- Trial name
- NCT00065299
- Testing
- Restricted phenylalanine diet
- Where
- 3 sites in United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Asthma-COPD Overlap Syndrome
This Study Include Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap Patients.Patients Were Vitamin D Deficient.Age Range 40-70 Years, Smokers.Patients Were Advised to Take Either Placebo or Vitamin D3.Lung Functions and Exercise Tolerance Were Assessed at Baseline and at 26th Weeks.
Vitamin D3 supplementation doen not change lung functions and exercise tolerance in vitamin D3 deficient ACO patient was the null hypothesis of the research.
- Trial name
- NCT03880734
- Testing
- Cholecalciferol
- Where
- Bangladesh
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Low Mood
Effect of a Nutritional Supplement on Mental Wellness in Adults
Trillions of microbes reside in human gut and constitute "gut microbiota". Composition of these microbes and substances produced by them play an important role in human health and wellness.
- Trial name
- NCT06058364
- Testing
- Intervention 1 - Triglyceride
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pharmavite LLC
Hormone Disturbance
An Exploratory Investigation of Dietary Supplementation and the Effect on Common Symptoms of Hormonal Imbalance
This is an open-label observational trial to study the effectiveness of a commercial dietary supplement and its effect on common symptoms of normal menstrual discomfort.
- Trial name
- NCT05328609
- Testing
- Semaine Hormonal Imbalance & The Daily
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Semaine Health
SARS-CoV Infection
Efficacy and Safety of Ozonised Oil (HOO) in COVID-19 Patients
The anti-viral efficacy of ozone against RNA viruses is already established. Ozone gas have been already proposed as possible therapy for Covid-19 infection with insofar limited success.
- Trial name
- HOO-COVID (NCT04651387)
- Testing
- Ozonized oil (HOO
- Sponsor
- Neuromed IRCCS
Type 2 Diabetes, Cardiovascular Diseases
Omega-3 Fatty Acids Supplementation and Atherothrombotic Biomarkers in Type 2 Diabetes and Cardiovascular Disease.
The major source of mortality and morbidity of diabetic patients is cardiovascular disease (CVD). Moreover, in CVD patients the presence of diabetes is associated with the increased risk of major adverse cardiac events as…
- Trial name
- NCT02178501
- Testing
- Omega-3 PUFA
- Where
- 2 sites in Poland
- Volunteers
- 126 people
- Sponsor
- Jagiellonian University
Pregnant Women, Pregnant Women and Their Offspring
Effectiveness of MMS Compared With IFS Among Pregnant Women in Bangladesh: an Experimental Study
Background Maternal undernutrition and micronutrient deficiencies remain highly prevalent in Bangladesh and contribute to maternal anaemia, low birth weight, preterm birth, and adverse neonatal outcomes.
- Trial name
- NCT07540130
- Testing
- Multiple micronutrient supplementation
- Where
- Bangladesh
- Volunteers
- 667 people
- Sponsor
- National Institute of Neurosciences and Hospital, Dhaka
Rhinitis
Rhinitis in the Elderly: The Role of Vitamin D
A study of the role of vitamin D in elderly subjects with perennial and/or nonallergic rhinitis. The hypothesis is that vitamin D supplementation will improve rhinitis symptoms and rhinitis related quality of life.
- Trial name
- NCT02272101
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Rohr and Columbo Asthma, Allergy and Immunology Specialists, P.C.
AICA-ribosiduria Due to ATIC Deficiency
Purine Supplementation in Patients With AICA-Ribosiduria
AICA-Ribosiduria due to ATIC deficiency is a rare genetic metabolic disease that affects less than 10 patients (PMID: 32557644).
- Trial name
- PURICA (NCT06845501)
- Testing
- purine-rich diet
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Infertility
A Randomized Controlled Study of Prolonging the Time of Progesterone Supplementation to Improve the Pregnancy Outcome of Single Day 6 Blastocyst Transfer of Freeze-thaw Cycle
This is a single-center, prospective, randomized controlled study. Patients with single blastocyst transfer in the freeze-thaw cycle, aged from 20 to 38 years, with less than three transfers, and with HRT-cycle single D6…
- Trial name
- NCT04938011
- Testing
- progesterone
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Nanjing University
Dietary Supplements, Intensive Care Unit
Vitamin D Supplementation in Intensive Care Unit Patients
A randomized controlled trial is designed to investigate the safety and clinical efficacy of a mega dose of VD in patients admitted in intensive care unit (ICU).
- Conditions
- Dietary Supplements, Intensive Care Unit, Vitamin D Deficiency, Vitamin D Toxicity
- Trial name
- NCT04915963
- Testing
- Vitamin D supplementation
- Volunteers
- 340 people
- Sponsor
- Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose
Homocystinuria
Proof of Concept Creatine Supplementation for Homocystinuria Study
Homocystinuria is a rare and inherited metabolic disorder, people with this condition don't have an enzyme needed to break down an amino acid called homocysteine.
- Trial name
- NCT06495567
- Testing
- Creatine, Dietary methionine tracer and protein intake
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
Use of Preoperative Postbiotic Supplementation in Colorectal Cancer Surgery
The treatment of colorectal cancer, in the absence of metastases, is primarily based on surgical removal. Colorectal surgery, which involves resecting part of the intestine and restoring intestinal continuity, carries a risk of…
- Trial name
- POSBIO-CRC (NCT07268846)
- Testing
- Postbiotic
- Where
- Brazil
- Volunteers
- 164 people
- Sponsor
- AC Camargo Cancer Center
Phenylketonurias
Evaluation of Low Phenylalanine Formulas
Ajinomoto Cambrooke has developed a PKU protein substitute that is a proprietary blend of purified Glycomacropeptide (GMP) and essential amino acids, under the brand name Glytactin®.
- Trial name
- NCT06332105
- Testing
- Glytactin, L-AA
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people
- Sponsor
- Ajinomoto Co., Inc.
Sarcopenia, Atrophy
Resistance Training in Elderly
In the present study the investigators aim to determine whether protein supplementation can augment the response to a 12 week resistance training program in healthy elderly men.
- Conditions
- Sarcopenia, Atrophy, Aging
- Trial name
- NCT00744094
- Testing
- protein drink, Resistance training
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Acute Myeloid Leukemia, Acute Lymphocytic Leukemia
Randomized Study: Standard of Care With or Without Atorvastatin for Prevention of GVHD for Matched Unrelated Donor BMT
Chronic Graft Versus Host Disease (GVHD) is one of the most challenging complications in long term survivors of allogeneic stem cell transplantation.
- Conditions
- Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Myelodysplastic Syndrome
- Trial name
- NCT03066466
- Testing
- Atorvastatin, Methotrexate, Tacrolimus
- Where
- United States
- Sponsor
- Loyola University
Osteoporosis, Aging
Vitamin D Supplementation in Older Women
The purpose of this study is to examine the effects of several doses of vitamin D on hormones related to bone, calcium absorption, bone density and muscle strength.
- Trial name
- VIDOS (NCT00472823)
- Testing
- Vitamin D3, Calcium Citrate (Citracal)
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- Creighton University
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