Clinical trials: Nutritional Supplement
Human Immunodeficiency Virus
Impact of NMN Supplementation on CD4+ T Cell Recovery in HIV Patients With Immunological Failure
This proof-of-concept study aims to investigate the potential impact of supplementing with Nicotinamide Mononucleotide (NMN), a direct precursor of NAD+ on CD4+ T cell recovery in virologically suppressed HIV patients…
- Trial name
- NCT06889142
- Testing
- Nicotinamide Mononucleotide
- Volunteers
- 7 people
- Sponsor
- TriHealth Inc.
Malnutrition, Oral Nutritional Supplementation
Representations of Oral Nutritional Supplementation (ONS) in Hospitals : Gender differences_observational Study
Over 30% of hospitalized patients are malnourished. These figures range from 20% to 60% in geriatric units. Undernutrition results either from a decrease in energy intake, an increase in needs, an increase in losses or a…
- Trial name
- CNO_ALIMS (NCT03588169)
- Testing
- semi-structured interviews
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anemia
School-Based Assessment of Micronutrient Interventions in Adolescents (SAMIA) in Zanzibar
This purpose of this study is to assess effects of iron and folic acid supplementation and multiple micronutrient supplementation on anemia status and school performance/attendance among in-school adolescents in Zanzibar…
- Trial name
- SAMIA (NCT05104554)
- Testing
- Iron and folic acid (IFA), Multiple Micronutrient Supplement (MMS)
- Where
- Tanzania
- Volunteers
- 2,480 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Carpal Tunnel Syndrome (CTS)
Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome
This study addresses the pressing clinical question of optimizing surgical and pharmacological interventions for severe Carpal Tunnel Syndrome (CTS), a prevalent and debilitating condition caused by median nerve compression.
- Trial name
- NCT06902831
- Testing
- Endoscopic Carpal Tunnel Release, Open carpal tunnel release, Neurotrophic supplementation
- Where
- Italy
- Volunteers
- 497 people
- Sponsor
- University of Bari
Colorectal Cancer (MSI-H), Malnutrition (Calorie)
Dietary Fiber and Probiotics in Advanced Colorectal Cancer
This single-center, prospective, randomized controlled trial was conducted to evaluate the efficacy of a 12-week combined dietary fiber and probiotic supplementation on gut microbiota, immune function, nutritional status, and…
- Trial name
- NCT07194954
- Testing
- Combined Dietary Fiber and Probiotics., Standard Nutritional Support
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Hospital of Hebei Medical University
Improvement in Immune Cell Function in Elderly Humans
Oral Glutathione Supplementation in Older Healthy Adults and Its Effect on the Number of Healthy Days Experienced During Four Months of Supplementation Compared to Placebo
A randomized, double blind placebo-controlled parallel intervention in adults over the age of 50 will be performed. Participants will receive a supplement capsule containing placebo (Crystalline Cellulose) or 500mg of Setria®…
- Trial name
- GSH (NCT02438956)
- Testing
- Setria glutathione supplement, Crystalline Cellulose
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Florida
Post-Menopausal Women
The Effect of 12-week Supplementation With Olive Leaf Extract in Postmenopausal Women (FEMMED)
Menopause is defined as the end of menstruation and fertility,starting 12 months after the last menstrual period.In this modern and economically developed society, most women are living for at least 20-40 years in a…
- Trial name
- FEMMED (NCT05744453)
- Testing
- Olive Leaf Extract, Cellulose
- Where
- Netherlands
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- BioActor
Hypertension
L-citrulline Supplementation, Cold Exposure, & Post-Exercise Muscle Ischemia
Cardiovascular disease (CVD) continues to be the major cause of morbidity and mortality in western countries. It has been shown that CVD events are known to be higher in the winter than in the summer.
- Trial name
- NCT02104375
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Florida State University
Muscle Damage, Inflammation
Compared Effect of a Fruit Milk Shake With a Protein-Carbohydrate Supplement on Recovery After Resistance Exercise
The aim of this study is to assess the effect of ingesting a commercial carbohydrate and protein dietary supplement in powder form (P-CHO supplement) or a milk shake with skimmed milk, strawberries and banana (MS), after…
- Conditions
- Muscle Damage, Inflammation, Oxidative Stress, Functional Recovery
- Trial name
- NCT01555775
- Testing
- P-CHO supplement, Fruit Milk Shake
- Where
- Portugal
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Iron Deficiency Without Anemia
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women
Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation.
- Trial name
- INFER 2 (NCT06851130)
- Testing
- ferrous sulfate 80 mg, ferrous sulfate 160 mg
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Swiss Federal Institute of Technology
Acne Vulgaris
Vitamin D Supplementation in Acne
The goal of this clinical trial is to compare in acne vulgaris patients. The main question it aims to answer is: To assess the therapeutic benefit of vitamin D supplement in acne vulgaris treatment, following a 2-month treatment…
- Trial name
- NCT06141330
- Testing
- D Max Drops, Azithromycin 250 milligram Oral Capsule, Adapalene
- Where
- Pakistan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- HITEC-Institute of Medical Sciences
Cognitive Decline, Aging
Effects of a Colon-delivered Multivitamin Supplement on Brain Functioning, Immunometabolic- and Intestinal Markers in Ageing
COMBI is a multi-center, randomized controlled trial among 70 older adults at risk of cognitive decline. The main goal is to investigate the effect of a 6-week colon-delivered multivitamin supplementation on the gut-brain axis in…
- Trial name
- COMBI (NCT05675007)
- Testing
- Colon-delivered multivitamin supplement
- Where
- 2 sites in Netherlands
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Donders Centre for Cognitive Neuroimaging
Type 2 Diabetes Mellitus
An Intervention Study on the Effect of Brazilian Spinach Supplementation on Health Outcomes Among Type 2 Diabetes Patients in Hospital Universiti Sains Malaysia
The purpose of this study is to determine whether Brazilian spinach supplementation effective in improving the nutritional status of Type 2 Diabetes Mellitus patient.
- Trial name
- NCT05727592
- Testing
- Althernanthera Sissoo, Dietary Consultation
- Where
- Malaysia
- Volunteers
- 87 people
- Sponsor
- Universiti Sains Malaysia
Gestational Diabetes
Evaluation of Iodine Supplementation in Women With Pregnancy Associated With Gestational Diabetes
Iodine supplementation during pregnancy is recommended by the high health authority and by the World Health Organization during pregnancy.
- Trial name
- IODIAB (NCT04683211)
- Testing
- Evaluation of iodine supplementation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Sud Francilien
Endothelial Dysfunction, Aging
Effects of Aronia Berries on Vascular Endothelial Function and the Gut Microbiota in Middle-Aged/Older Adults
Aging is the primary risk factor for cardiovascular disease (CVD) largely due to vascular endothelial dysfunction, a major initial step in the development of atherosclerosis.
- Trial name
- NCT03824041
- Testing
- Aronia full spectrum - half dose, Aronia full spectrum - full dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Blepharospasm, Hemifacial Spasm
Testing the Effect of Zinc Supplementation to Improve the Treatment Effect of Botulinum Toxin for Oculofacial Spasm
The purpose of this study is to determine whether zinc supplements are effective in enhancing the treatment of oculofacial spasm disorders with botulinum toxin.
- Trial name
- NCT01546805
- Testing
- Zinc Supplement, Sugar pill
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Pre-eclampsia, Pregnancy
Evaluation of the Efficacy of Citrulline Supplementation on the Delay of Delivery for Women Hospitalized for Pre-eclampsia (CITRUPE)
Pre-eclampsia (PE) complicates 2-8 % of pregnancies and is associated with high maternal and fetal morbidity and mortality. The early clinical manifestations are the occurrence of a maternal blood pressure and proteinuria.
- Trial name
- CITRUPE (NCT02801695)
- Testing
- Citrulline
- Where
- 2 sites in France
- Volunteers
- 116 people
- Sponsor
- Nantes University Hospital
Knee Discomfort
Influence of Instaflex Advanced Supplement on Joint Function
Joint discomfort is reported by 32% of U.S. adults, and increases with age. The knee is the most common site of joint discomfort regardless of age.
- Trial name
- NCT03041077
- Testing
- Instaflex Advanced
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Cognition - Other, Strength Outcomes
Effects of Alpha-GPC on Muscle Power, GH Levels, and Cognitive Function
Purpose: To determine the effects of low dose and high dose Alpha-GPC on cognitive performance, muscle performance, and serum growth hormone levels.
- Trial name
- NCT06690619
- Testing
- 315 mg Alpha-GPC, 630 mg Alpha-GPC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Vitamin D Deficiency, Hemodialysis Patient
Cholecalciferol Supplementation Effect on Parathyroid Hormone in Hemodialysis Patients
Introduction. Vitamin D regulates mineral metabolism. Its deficiency has been associated with diabetes, cancer and increased mortality. 25OH vitamin D (25VD) is stable and suitable for the evaluation of vitamin D sufficiency.
- Trial name
- NCT03648528
- Testing
- cholecalciferol
- Volunteers
- 120 people
- Sponsor
- Cooperativa Asistencia Sindicato Médico Uruguay
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