Clinical trials: OA Knee Pain
Osteoarthritis (OA) of the Knee
Knee Pain and Lumbar Proprioception in Knee Osteoarthritis Patients
Knee osteoarthritis (KOA), is a chronic degenerative joint pathology with a global prevalence of 22.9% in individuals aged 40 and over.
- Trial name
- NCT07436897
- Testing
- porprioception
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Cairo University
Osteoarthritis, Osteoarthritis (OA) of the Knee
Systemic Oral Glucocorticoids for the Treatment of Acute Osteoarthritis Pain in the Emergency Department
The purpose of this clinical trial is to compare the analgesic effects (relief of pain) of glucocorticoids (steroids) and pain medication versus pain medication alone in adult patients presenting to the emergency department with…
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Shoulder, Osteoarthritis (OA) of the Hip
- Trial name
- NCT06603662
- Testing
- Prednisone, Dexamethasone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- WellSpan Health
Medial Compartment Osteoarthritis of the Knee
High Tibial Osteotomy (HTO) With or Without Arthroscopy of the Knee Joint
Participants will be randomized to undergo a High Tibial Osteotomy (HTO) with or without a knee scope. Patients will be tested in the Gait Lab, will fill out quality-of-life questionnaires, and have a clinical evaluation done…
- Trial name
- NCT01614288
- Testing
- knee Arthroscopy, No arthroscopy
- Where
- Canada
- Sponsor
- University of Western Ontario, Canada
Knee Osteoarthritis, Pain
Effects of Voodoo Flossing Technique in Knee Osteoarthritis Patients
Knee osteoarthritis (KOA) is a prevalent degenerative joint disease characterized by pain, stiffness, and reduced physical function, significantly impacting quality of life especially in elderly population.
- Conditions
- Knee Osteoarthritis, Pain, Range of Motion, Physiotherapy
- Trial name
- NCT06986694
- Testing
- Group A will receive Voodoo Flossing Technique along with aerobic and strengthening exercises & conventional physiotherapy protocol for Knee OA., Group B will receive aerobic and strength training and conventional physiotherapy protocol for knee OA only.
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
An Evaluation of the Graded Weight-bearing Exercise in Patients With Knee Osteoarthritis.
Background: Knee osteoarthritis is the most common disorder impacting the synovial joint. The prevalence of osteoarthritis rises with age, and its consequences on health and socioeconomic are significant, which emphasize the need…
- Trial name
- NCT05671146
- Testing
- anti-gravity treadmill, Weight-bearing exercises for knee flexors and extensors, Non weight-bearing exercises for knee flexors and extensors
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Osteo Arthritis Knee, Pain, Chronic
Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis
Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities.
- Trial name
- NCT03886142
- Testing
- radiofrequency, platelet rich plasma injection
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Osteoarthritis of Knee, Blood Flow Restriction Exercise
Blood Flow Restriction Exercises and Conservative Exercises in Knee Osteoarthritis
Knee osteoarthritis (OA) is a rheumatic disease that causes serious cartilage damage in the knee joint. Moderate physical activity can slow cartilage degeneration in moderate OA stages.
- Conditions
- Osteoarthritis of Knee, Blood Flow Restriction Exercise, Resistance Training, Occlusion Training
- Trial name
- NCT04535596
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Istanbul Medipol University Hospital
Total Knee Anthroplasty, Knee Osteoarthritis
IPACK vs Adductor Magnus Plane Block Added to Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty (TKA) is among the most frequently performed surgical procedures for degenerative joint diseases, including advanced knee osteoarthritis, rheumatoid arthritis, and post-traumatic arthritis.
- Conditions
- Total Knee Anthroplasty, Knee Osteoarthritis, Postoperative Pain Management
- Trial name
- NCT07643883
- Testing
- ACB+IPACK, ACB+AMM
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Osteoarthritis of the Knee
Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee
The purpose of this trial is to investigate the efficacy and safety of OLT1177 Gel in subjects with moderate to severe pain associated with osteoarthritis of the knee following cessation of pain therapy.
- Trial name
- NCT01768975
- Testing
- OLT1177 Gel
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Olatec Therapeutics, Inc.
Osteoarthritis, Knee
A Study Comparing Viscosupplementation and Corticosteroid Injections for Knee Osteoarthritis
Do differences exist between patients who receive a single intra-articular injection of corticosteroid versus patients who receive a single intra-articular injection of hyaluronic acid for the treatment of knee osteoarthritis at…
- Trial name
- NCT01132677
- Testing
- Hylan G-F 20 (Synvisc One), Methylprednisolone (Corticosteroid)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- LifeMark Health
Knee Osteoarthritis
Effects of Platelet-Rich Plasma and Ozone Therapy in Knee Osteoarthritis
Knee osteoarthritis can frequently occur with advancing age. In cases of pain that persists despite hot/cold applications, drug therapy and exercise, intra-articular injections are considered.
- Trial name
- NCT06631456
- Testing
- PRP injection, Ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Chronic Knee Pain, Osteoarthritis, Knee
JointADventure: A Worksite Activity-Diet Intervention for Chronic Knee Pain
JointADventure: A worksite activity-diet intervention for chronic knee pain is a randomized controlled trial evaluation of a physical activity and nutritional worksite intervention to decrease symptoms and disability associated…
- Trial name
- NCT01977872
- Testing
- A worksite activity-diet intervention
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Northwestern University
Knee Osteoarthritis
Educational Program for Knee Osteoarthritis
Sixty patients with a diagnosis of knee osteoarthritis, aged between 40 and 80 years, of both genders were included. The patients were divided into: experimental group that carried out an educational program - 5 consecutive…
- Trial name
- NCT03588195
- Testing
- Educational Program, Transcutaneous Nerve Electro-Stimulation
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Knee Osteoarthritis
Exercise Dosages and Exercise Adherence With Patients With Knee Osteoarthritis
Although the effects of different exercise dosages for patients with osteoarthritis are compared in the literature, it is seen that studies on which exercise dosage is better are insufficient.The planned study has 2 main…
- Trial name
- Adherence (NCT04357145)
- Testing
- High Dosage Home Exercise Training, Standard Dosage Home Exercise Training
- Volunteers
- 60 people
- Sponsor
- Marmara University
Osteoarthritis, Knee
Two Standardized Radial Pressure Wave Techniques Versus Pain-Site Guided Therapy in Patients With Knee Osteoarthritis.
The goal of this clinical trial is to evaluate and compare the effectiveness of radial pressure wave therapy (RPWT) applied at different anatomical sites in patients with knee osteoarthritis (OA) over a follow-up of four months.
- Trial name
- NCT06622512
- Testing
- Radial Pressure Wave Therapy
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- Hospital Civil de Guadalajara
Knee Osteoarthritis, Pain, Musculoskeletal
Intra-articular Corticosteroid Injection in GAE for Knee Knee Osteoarthritis
The goal of this clinical trial is to investigate the effectiveness and safety of intra-articular corticosteroid injection (IACI) in alleviating post-procedural pain and improving early outcomes in patients undergoing geniculate…
- Trial name
- NCT06514716
- Testing
- Geniculate Artery Embolization with Intra-articular Corticosteroid Injection (GAE with IACI), Geniculate Artery Embolization alone (GAE alone)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Knee Osteoarthritis
Combined Application of Electrical Stimulated Antagonist Contraction During Walking (Walking Study)
Osteoarthritis of the knee (KOA) is the most common cause of disability in older adults. Osteoarthritis involves a loss of cartilage, which acts like a cushion between the bones as well as changes in the bones of joints.
- Trial name
- NCT02730598
- Testing
- Hybrid Training System (HTS), Sensory TENS
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Kansas Medical Center
Knee Osteoarthritis, Medial Compartment Knee Osteoarthritis
A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis
A Phase 2a, multicenter, randomized, double-blind, parallel group, placebo-controlled study to evaluate the safety, tolerability, efficacy and pharmacokinetic/pharmacodynamic effect of ABT-981 in patients with symptomatic…
- Trial name
- NCT02087904
- Testing
- ABT-981
- Volunteers
- 350 people
- Sponsor
- AbbVie
Osteoarthritis, Knee
Delivra-Celecoxib 8% Cream and Osteoarthritis
The observation of the clinical use of the Delivra Celecoxib cream (8%) in the treatment of osteoarthritis of the knee. Observations will be made over 12 weeks of treatment.
- Trial name
- Del-Cel (NCT03882749)
- Where
- 3 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Delivra, Inc.
Knee Osteoarthrosis
Conservative Management vs. Arthroplasty in Knee Osteoarthritis
The goal of this observational study is to learn about the long-term effects of a non-surgical management programme in people with osteoarthritis that are eligible for a knee joint replacement surgery to treat their knee…
- Trial name
- NCT06623149
- Testing
- Non-Surgical Intervention, Current practice
- Where
- 6 sites in Denmark
- Volunteers
- 2,500 people
- Sponsor
- Marius Henriksen