Clinical trials: OAT
Healthy
Chronic Cardiovascular and Gut-bacteria Effects of Phenolic Rich Oats in Adults With Above Average Blood Pressure
In this proposed human trial, the investigators aim to establish whether 4 weeks of daily consumption of beta-glucan matched meals providing either a high dose or a moderate dose of oat avenanthramides and phenolic acids leads to…
- Trial name
- NCT02847312
- Testing
- High avenanthramide, phenolic acid, Low avenanthramide, medium phenolic acid, Control
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hypercholesterolemia
Lipid Lowering Effect of Plant Stanol Ester in a Spoonable Non-dairy Product
The aim is to determine the effect of investigational products on serum LDL cholesterol.
- Trial name
- NCT05064644
- Testing
- Product that contains plant stanol ester
- Where
- Finland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Raisio Group
Bioavailability, Metabolism
Bioavailability and Metabolism of Avenanthramide: a Novel Oat Phytochemical
The purpose of the study is to examine whether orally ingested oat avenanthramides (AVA) in oat flour cookies are bioavailable in humans by measuring plasma and urine concentrations of AVAs and their potential metabolites after…
- Conditions
- Bioavailability, Metabolism, Avenanthramides
- Trial name
- NCT02415374
- Testing
- Avenanthramides
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Metabolic Syndrome
The Effect of Oat Processing on Gastric Emptying and Satiety Induced After Consuming Porridge
This crossover study is designed to compare the gastric layering and rates of emptying and by inference rates of digestion of two different porridge meals prepared from either finely milled or flaked oats.
- Trial name
- Oatmet (NCT02655367)
- Testing
- Flaked oats, Milled oats
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Healthy
Phenolic-rich Oats and Artery Improvement
In this proposed human trial, the investigators aim to establish whether consumption of one portion of phenolic acid-rich oats leads to acute improvements (i.e.
- Trial name
- PROGRAIN2 (NCT02731755)
- Testing
- Oat, Control
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Reading
Gastrointestinal Disorder, Functional
Effect of Oat Bran on Bowel Function and Appetite
The consumption of oat bran fiber also has a significant bulking effect in humans. However, besides fecal bulk, dietary fiber can promote gut health in other ways.
- Trial name
- OATGUT (NCT03014141)
- Testing
- Oat bran (Oatwell 28), Maltodextrin
- Volunteers
- healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Kidney Disease
Evaluation of Renal Drug Transport in Healthy Volunteers
The process of drug elimination that occurs within the kidneys is complex, and involves filtration, secretion and absorptive mechanisms.
- Trial name
- NCT00690014
- Testing
- probenecid
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Unidentified Gastrointestinal Symptoms Following Gluten-free Oats Consumption
Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 1
The research aims to investigate the effects of gluten-free oats to the gastrointestinal health in celiac disease patients and healthy subjects.
- Trial name
- NCT02764931
- Testing
- Gluten free oats and gastrointestinal health
- Where
- Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Turku
Cardiovascular Disease, Hypercholesterolemia
Health Benefits of Whole Grain Oats in Population at Risk of Cardio-metabolic Disease
Intake of whole grain cereals has been associated with reducing the risk of hyperlipidaemia and heart disease, however the mechanisms by which oats or oat fractions exert this effect is not totally clear.
- Trial name
- NCT01925365
- Testing
- wholegrain cereals oats (WGO), Non wholegrain cereals
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Reading
Head and Neck Cancer, Healthy
Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Multispectral Optoacoustic Tomography (MSOT) is a promising imaging technology that utilizes pulsed laser light. One of the key capabilities of this technology is measuring oxygenation within human tissue.
- Trial name
- msotcmfflap (NCT06716892)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Eye Diseases Hereditary, Retinal Disease
Inherited Retinal Degenerative Disease Registry
The My Retina Tracker® Registry is sponsored by the Foundation Fighting Blindness and is for people affected by one of the rare inherited retinal degenerative diseases studied by the Foundation.
- Conditions
- Eye Diseases Hereditary, Retinal Disease, Achromatopsia, Bardet-Biedl Syndrome
- Trial name
- MRTR (NCT02435940)
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Foundation Fighting Blindness
Human Health, Polyphenols
Avenanthramide and Saponin Bioavailability in Oat Bran
Avenanthramides and saponins are types of chemical compounds found naturally in oats. Avenanthramides have anti-oxidant properties, anti-atherosclerotic, anti-inflammation, and anti-proliferative effects on cancer cells in vitro.
- Conditions
- Human Health, Polyphenols, Pharmacokinetics
- Trial name
- NCT04335435
- Testing
- Oat Bran Consumption
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Sjogren Syndrome, Malignant Tumors
The Feasibility of Multispectral Optoacoustic Tomography in Different Diseases
Optoacoustic imaging is a new and innovative imaging technique that combines the high contrast of optical imaging with the penetration depth and high spatial resolution of ultrasonography using the optoacoustic effect.
- Conditions
- Sjogren Syndrome, Malignant Tumors, Arterial Disease
- Trial name
- FOMO (NCT06740175)
- Testing
- Multispectral optoacoustic tomography
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Consumer Research, General Population
Attidutes and Understanding of Oat Fibre Claims on Food Labels
Oat fibre consumption has been shown to lower blood cholesterol, which is advantageous for heart health. Oat and fibre claims on food labels should help people find heart healthy food choices; however consumer attitudes and…
- Trial name
- NCT01932827
- Testing
- Mock Package Questionnaire
- Where
- Canada
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Food Intake, Satiety
The Effect of Oat Based Breakfast Cereals on Satiety and Food Intake
This study is to determine if two breakfasts of equivalent calories, an oat based breakfast cereal or a ready-to-eat cereal, provide the same satiety benefits.
- Trial name
- NCT01666574
- Testing
- Test cereal 1, Oat-based, Test Cereal 2, Oat based
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Centronuclear Myopathy
Multispectral Optoacoustic Tomography for Advanced Imaging of Centronuclear Myopathy
Twenty patients with centronuclear myopathy and twenty age- and sex-matched, muscle-healthy controls will undergo diagnostic examination.
- Trial name
- MOSAIC (NCT07021820)
- Testing
- MSOT
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Glucose Intolerance
Effect of Consuming Oat Bran Mixed in Water Before a Meal on Glycemic Responses in Healthy Humans - a Pilot Study
Viscous dietary fibers including oat β-glucan are one of the most effective classes of functional food ingredients for reducing postprandial blood glucose.
- Trial name
- NCT02801916
- Testing
- 0 grams oat bran, 4.5 grams oat bran, 13.6 grams oat bran
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Healthy
Oat Phenolics Bioavailability
A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains.
- Trial name
- NCT02574039
- Testing
- Oat bran, refined grain
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Reading
Digestive System Disease, Inflammatory Bowel Diseases
Optoacoustic Characterization of Postprandial Intestinal Blood Flow
Inflammatory activities in the gastrointestinal tract are accompanied by an increase in blood flow in the intestinal wall layers of the respective organs.
- Trial name
- NEPOMUC (NCT05160077)
- Testing
- Multispectral optoacoustic tomography (MSOT)
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Smoking Reduction
The Potential Effect of Avena Sativa L. on Wellness/Wellbeing During Smoking Reduction/Cessation Experience
The purpose of this study is to evaluate the potential effect of Avena Sativa L. on wellbeing during smoking reduction/cessation
- Trial name
- SMOK (NCT04749017)
- Testing
- Experimental product consumption, Control product consumption
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia