Clinical trials: OCD
Parkinson's Disease, Obsessive-Compulsive Disorder
Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD
The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive…
- Trial name
- NCT00790634
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Depression, Panic Disorder
Evaluating the Effects of Stress in Pregnancy
This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy.
- Conditions
- Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00525226
- Where
- United States
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Emory University
Anxiety Disorders, Depressive Disorder
Transdiagnostic Treatment Personalization
The primary purpose of this study is to explore whether the efficiency of treatment for anxiety and depressive disorders can be increased using two discrete strategies: personalized skill ordering and 2) treatment discontinuation…
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04584879
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Obsessive Compulsive Disorder
Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder
This experiment will examine if the use of computerized tasks that train individuals to control their attention more effectively will predict individual differences in obsessive-compulsive symptoms, rumination and BDNF change.
- Trial name
- CCT-OC (NCT01414023)
- Testing
- Cognitive Control Training, Peripheral Vision Task
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Obsessive-Compulsive Disorder
Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- NCT03457675
- Testing
- Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period
- Where
- 3 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Psychiatric Neurosurgery (PNS) for Obsessive Compulsive Disorder (OCD): A Qualitative Analysis of Patient and Family Member Experiences
In this study the investigators will use semi-structured interviews to qualitatively analyse patient and family member experiences with either deep brain stimulation or other forms of psychiatric neurosurgery.
- Trial name
- NCT02537795
- Testing
- deep brain stimulation, anterior capsulotomy
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
OCD - Osteochondritis Dissecans
MRI Findings of Epiphyseal Growth Plate in Healthy Children
The purpose of the study is to determine if by using MRI changes can be identified changes early on in the knees of young children that may be at risk for developing osteochondritis dissecans.
- Trial name
- NCT03190200
- Testing
- MRI
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Posttraumatic Stress Disorder, Somatization
Intervention Through EMDR and CBT With Women Victim of Childhood Sexual Abuse. A Randomized Controlled Trial.
This study evaluates the effectiveness of two types of therapy for the treatment of sexual abuse psychological impact on a sample of Spanish women.
- Conditions
- Posttraumatic Stress Disorder, Somatization, Obsessive-Compulsive Disorder, Depression
- Trial name
- NCT04813224
- Testing
- TRAUMA CENTERED EMDR-BASED TREATMENT and TRAUMA-FOCUSED CBT-BASED TREATMENT
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Obsessive-Compulsive Disorder
Exposure and Response Prevention With Behavioral- Versus Cognitive Therapy Rationale in Obsessive Compulsive Disorder
The aim of the study is to determine whether exposure and response prevention (ERP) is more effective when patients are presented with a behavioral therapy versus cognitive therapy rationale in the treatment of…
- Trial name
- NCT00184262
- Testing
- ERP cognitive therapy, ERP behavioral therapy
- Where
- Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety, Obsessive-Compulsive Disorder
Virtual Reality System for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. The investigators aim to enhance this therapy with the use of virtual reality exposures.
- Trial name
- NCT03636022
- Testing
- VR System, Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Obsessive Compulsive Disorder
Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
This study will test the hypotheses that: 1. 12 weeks of Luvox-CR plus web-based Cognitive-Behavioral Therapy (CBT) [CT-STEPS] will produce greater symptom relief of OCD than treatment with Luvox-CR alone; and, 2.
- Trial name
- NCT00743834
- Testing
- Luvox CR, Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rogers Center for Research & Training, Inc.
Obsessive-Compulsive Disorder
A Controlled Trial of Daily Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
Pediatric obsessive-compulsive disorder (OCD) is a chronic and often disabling illness with an estimated lifetime prevalence of 1 to 3%.
- Trial name
- NCT00369642
- Testing
- Cognitive-behavioral therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety Disorders, Obsessive Compulsive Disorder
Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders
This study will look at similarities and differences in family processes and child temperament among children with and without symptoms of anxiety disorders.
- Trial name
- NCT00517244
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Obsessive-compulsive Disorder
D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder
Cognitive-behavioral therapy (CBT) has proven efficacy for treatment of pediatric obsessive-compulsive disorder (OCD). Yet, CBT does not help all children and those who benefit often remain symptomatic upon treatment completion.
- Trial name
- NCT00864123
- Testing
- Cognitive-behavioral therapy, D-cycloserine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Healthy, Mental Disorder
I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers
Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse.
- Conditions
- Healthy, Mental Disorder, Obsessive Compulsive Disorder, Schizophrenia
- Trial name
- NCT00001771
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Impulsive Behavior, Impulse Disorders
Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
The objective of this prospective observational cohort study is to answer the following clinically important questions: 1. In patients with a pre-operative history of ICBs, what is the likelihood of improvement or deterioration…
- Conditions
- Impulsive Behavior, Impulse Disorders, Gambling, Pathological, Eating, Binge
- Trial name
- CRIPS (NCT04811807)
- Testing
- Subthalamic Nucleaus Deep brain stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King's College London
Experimental Video Games, Behavioral Assessment
Gamified Digital Intervention to Enhance the Efficacy of Exposure Therapy for OCD
Aim 1 - Clinically analyze the game Militant of the Maze (MoM) as a vehicle for Exposure Theory, including, play, observation, and feedback from five clinicians.
- Trial name
- NCT05850312
- Testing
- Gamified Digital Intervention - Feasibility Analysis on MoM, Gamified Digital Intervention
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Idaho State University
Obsessive-Compulsive Disorder
Effectiveness of a Self-guided Mobile Application in Improving Obsessive Compulsive Disorder Symptoms
Obsessive Compulsive Disorder (OCD) is a significant mental health problem worldwide. OCD typically begins in young adulthood, and without adequate intervention, often takes a chronic course.
- Trial name
- NCT06202677
- Testing
- Self-guided program on obsessive compulsive disorder, Self-guided program on cooperation
- Where
- Singapore
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National University of Singapore