Clinical trials: OCD
Trichotillomania
Trichotillomania: Group Cognitive-Behavioral Therapy
Objective: Trichotillomania is a psychiatric condition characterized by chronic pulling and plucking of one's own hair. Cognitive behavioral therapy shows promise as a treatment.
- Trial name
- NCT01968343
- Testing
- Cognitive-behavioral therapy., Supportive therapy.
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Obsessive-Compulsive Disorder, OCD
Neurofeedback for Treatment-resistant Obsessive-compulsive Disorder (OCD)
The aim of this study is to teach participants with a OCD diagnosis and treatment-resistance how to decrease the response from a brain region involved in the disease by using a technique called neurofeedback.
- Trial name
- NCT03956771
- Testing
- Real neurofeedback
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- Pedro Morgado
PTSD, OCD
Differences in Cognitive Performance and Brain Activity Between Patients With PTSD and OCD
Comparison of the neurophysiological response of OCD and PTSD patients (both considered anxiety syndromes) in error processing. The patients will perform three computerized tasks while a net of electrodes (for EEG measurement)…
- Trial name
- NCT01723033
- Volunteers
- 30 people
- Sponsor
- Beersheva Mental Health Center
Obsessive-Compulsive Disorder
Pilot Study of CBT With tDCS for Adults Being Treated for Obsessive Compulsive Disorder
This pilot study aims to compare the effect of transcranial direct current stimulation (tDCS) versus sham stimulation, delivered immediately prior to cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD), on…
- Trial name
- NCT05964998
- Testing
- transcranial direct current stimulation
- Where
- United States
- Sponsor
- Rogers Behavioral Health
Obsessive-Compulsive Disorder
Digital Health Interventions for Obsessive Compulsive Disorder (OCD)
The investigators are testing two digital health interventions for obsessive compulsive disorder (OCD). The investigators hope that these digital health programs will increase access to treatment for OCD.
- Trial name
- NCT04136626
- Testing
- Perspectives OCD, The Health and Well-Being Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Neuroimaging Biomarkers for Predicting rTMS Response in OCD
This study evaluates an accelerated schedule of theta-burst stimulation using a Transcranial Magnetic Stimulation (TMS) device for treatment-resistant Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT04286126
- Testing
- Active bilateral DMPFC, Active right-sided OFC
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Phobia, Social, Panic Disorder
Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders
Selective serotonin reuptake inhibitors (SSRIs) including sertraline have been found to be effective in the treatment of generalized social phobia (GSP).
- Conditions
- Phobia, Social, Panic Disorder, Agoraphobia, Obsessive-Compulsive Disorder
- Trial name
- NCT00182533
- Testing
- Sertraline
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Hamilton Health Sciences Corporation
Generalized Anxiety Disorder
Pilot Study of Virtual Reality for Providing Exposure Therapy to Children
Drs. from the Mayo Clinic Rochester will plan and execute a feasibility study of the phase I prototype version of the Virtual Reality exposure therapy system. Dr.
- Trial name
- NCT03208348
- Testing
- Pilot Virtual Reality
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Obsessive Compulsive Disorder
Group Cognitive Behavioral Therapy Versus Fluoxetine for Obsessive-Compulsive Disorder: a Practical Trial
First line treatments fo Obsessive Compulsive Disorder (OCD) are Selective Serotonin Recapture Inhibitors (SSRIs) and Cognitive Behaviour Therapy (CBT) including exposure with response prevention.
- Trial name
- GCBTVF (NCT00680602)
- Testing
- Group Cognitive Behavior Therapy, SSRI (fluoxetine, sertraline, paroxetine, citalopram)
- Where
- Brazil
- Volunteers
- 158 people
- Sponsor
- University of Sao Paulo
Obsessive Compulsive Disorder
Internet Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)
The main aim of this study is to test whether cognitive behavior therapy could be effective in treating obsessive compulsive disorder.
- Trial name
- NCT01348529
- Testing
- Internet CBT
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder
Individually Targeted Neuromodulation for Contamination-based OCD
Patients with obsessive-compulsive disorder (OCD) experience a wide array of different types of obsessions and compulsions. However, current treatments for OCD employ a "one size fits all" approach and are used for all patients…
- Trial name
- NCT05048251
- Testing
- cTBS, iTBS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mclean Hospital
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Obsessive Compulsive Disorder
Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
This study will test the hypotheses that: 1. 12 weeks of Luvox-CR plus web-based Cognitive-Behavioral Therapy (CBT) [CT-STEPS] will produce greater symptom relief of OCD than treatment with Luvox-CR alone; and, 2.
- Trial name
- NCT00743834
- Testing
- Luvox CR, Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rogers Center for Research & Training, Inc.
Obsessive-compulsive Disorder
Brief Intervention for OCD Fears
The study will test the efficacy of propranolol or placebo, administered after reactivation of a previously acquired obsessive-compulsive disorder (OCD) fear, in reducing fear and avoidance in OCD.
- Trial name
- NCT02790710
- Testing
- Propanolol
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Dealing With Intrusive Thoughts in OCD - a Comparison of Detached Mindfulness and Cognitive Restructuring
The purpose of this study is to assess and compare the overall efficacy and differential effects of detached mindfulness and cognitive restructuring in the treatment of patients with obsessive-compulsive disorder.
- Trial name
- NCT03002753
- Testing
- detached mindfulness, cognitive restructuring
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Christoph-Dornier-Stiftung für Klinische Psychologie
Obsessive-Compulsive Disorder (OCD), Transcranial Magnetic Stimulation
Continuous Theta-Burst Stimulation for Obsessive-Compulsive Disorder: An Open-Label Study
This single-arm, open-label study evaluates short-term symptom improvement and tolerability of continuous theta-burst stimulation (cTBS), a non-invasive brain stimulation technique, in adults with obsessive-compulsive disorder…
- Conditions
- Obsessive-Compulsive Disorder (OCD), Transcranial Magnetic Stimulation, Electroencephalography
- Trial name
- NCT07896837
- Testing
- Continuous Theta-Burst Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Social Anxiety Disorder, Specific Phobia
Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
The collection of patient self-report and diagnostic data will allow us to examine the efficacy of the treatment delivered in the McLean Anxiety Mastery Program.
- Conditions
- Social Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Panic Disorder
- Trial name
- NCT02305537
- Testing
- McLean Anxiety Mastery Program
- Where
- United States
- Volunteers
- 559 people
- Sponsor
- Mclean Hospital
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anxiety Disorders, Obsessive Compulsive Disorder
Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders
This study will look at similarities and differences in family processes and child temperament among children with and without symptoms of anxiety disorders.
- Trial name
- NCT00517244
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Obsessive-Compulsive Disorder
Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- NCT03457675
- Testing
- Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period
- Where
- 3 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine