Clinical trials: OCD, open to volunteers
Obsessive Compulsive Disorder (OCD)
Gamified Combined Cognitive Bias Modification in Adults Diagnosed With OCD: Randomized Controlled Trial
This randomized controlled trial examines the effects of a mobile-based gamified combined cognitive bias modification (CBM-C) intervention on obsessive-compulsive symptoms, obsessive beliefs, attentional and interpretation…
- Trial name
- NCT06941155
- Testing
- Gamified-Combined Cognitive Bias Modification, Standard Combined Cognitive Bias Modification
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Obsessive Compulsive Disorder (OCD)
Artificial Intelligence-Powered Virtual Reality Exposure Therapy for OCD in College Students: A Proof-of-Concept Study
This research study is being conducted to study the use of artificial-intelligence powered virtual reality exposure therapy (AI-VRET) to treat college students with obsessive compulsive disorder (OCD).
- Trial name
- AI-VRET (NCT07877363)
- Testing
- Traditional Exposure and Response Prevention (ERP), Artificial Intelligence-Powered Virtual Reality Exposure Therapy (AI-VRET)
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Obsessive Compulsive Disorder (OCD)
Low-intensity Ultrasound for Individuals With Obsessive-compulsive Disorder
The goal of this clinical trial is to learn whether low-intensity focused ultrasound (LIFU), a non-invasive form of brain stimulation, can change brain activity and improve thinking and decision-making in adults with…
- Trial name
- LIFU-OCD (NCT07872917)
- Testing
- Low-intensity focused ultrasound (Active)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Chondral Defect, Osteochondritis Dissecans (OCD)
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of participants aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the…
- Conditions
- Chondral Defect, Osteochondritis Dissecans (OCD), Articular Cartilage Defect, Articular Cartilage Disorder of Knee
- Trial name
- PEAK (NCT03588975)
- Testing
- MACI, microfracture
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Vericel Corporation
Obsessive-Compulsive Disorder (OCD)
A Digital Mindfulness-Based Program for OCD
Obsessive-Compulsive Disorder (OCD) is a common long-lasting, and disabling condition, affecting 1 in every 25 people in Portugal.
- Trial name
- MBCT-OCD (NCT07871344)
- Testing
- Mindfulness-based cognitive-behavioral therapy digital program
- Volunteers
- 128 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Anxiety Disorders, OCD
Digital Coach to Support Exposure Therapy Homework for Anxious Youth
This study is testing a digital tool called BraveBot for young people who are receiving cognitive behavioral therapy (CBT) for anxiety, OCD, or related problems. BraveBot is a computer program, not a person.
- Trial name
- NCT07666672
- Testing
- BraveBot, Self-Guided Exposure Therapy Homework
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Osteochondral Lesions of the Knee Joint, Osteochondritis Dissecans (OCD)
MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
The present study aims to compare the efficacy and the safety of MaioRegen Prime to Debridement (SSOC) in patients with deep osteochondral lesions of the knee joint.
- Conditions
- Osteochondral Lesions of the Knee Joint, Osteochondritis Dissecans (OCD), Early Osteoarthritis
- Trial name
- OSTEOCONFIRM (NCT07332182)
- Testing
- osteochondral scaffold implant, SSOC
- Where
- 10 sites in United States, Italy
- Volunteers
- 400 people
- Sponsor
- Fin-Ceramica Faenza Spa
ADHD, Obsessive Compulsive Disorder (OCD)
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)
Background: Attention deficit hyperactivity disorder (ADHD) is common in children. It can cause problems with attention and the ability to control actions and impulses.
- Conditions
- ADHD, Obsessive Compulsive Disorder (OCD), Healthy Volunteer
- Trial name
- NCT07566468
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder (OCD)
Feasibility of Modulating Cognitive Control in OCD
This study tests out procedures to look at whether a type of brain stimulation called transcranial magnetic stimulation impacts flexible shifts in behavior in obsessive-compulsive disorder (OCD).
- Trial name
- NCT07419009
- Testing
- continuous theta-burst transcranial magnetic stimulation (cTBS)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obsessive-Compulsive Disorder (OCD)
Neurobehavioral Investigations of Approach Dynamics in the Ventral Striatum
Traditional strategies for diagnosing psychiatric disorders focus on definitions based on constellations of co-occurring symptoms.
- Trial name
- NCT05422469
- Testing
- Medtronic Percept RC neurostimulator
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Baylor College of Medicine
Obsessive Compulsive Disorder (OCD)
OCD LIFU Target Engagement
The investigators will conduct a pilot study to evaluate the safety and feasibility of low-intensity focused ultrasound on obsessive-compulsive disorder (OCD) symptoms when delivered to subcortical brain targets.
- Trial name
- NCT07558148
- Testing
- Low Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Depression, Anxiety
Focused Ultrasound for Behavioral Health
This is a double-blind, within-participant crossover, multi-site dose-finding study evaluating the safety, feasibility, and preliminary efficacy of repeated low-intensity focused ultrasound (LIFU) stimulation using the ATTN201…
- Conditions
- Depression, Anxiety, Obsessive Compulsive Disorder (OCD)
- Trial name
- VANTUS (NCT07851038)
- Testing
- ATTN201 head-worn focused ultrasound
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Attune Neurosciences Inc
Obsessive-Compulsive Disorder (OCD)
Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms
The purpose of this study is to examine the acute effects of exercise on cognitive flexibility and symptom reactivity. The main questions it aims to answer are: Does moderate intensity physical activity reduce subjective…
- Trial name
- NCT07103902
- Testing
- Moderate-Intensity Exercise, Low-Intensity Exercise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Obsessive-Compulsive Disorder (OCD)
Acceptance and Commitment Therapy for Religious OCD
The purpose of the study is to examine the effects and feasibility of a specific form of psychotherapy, acceptance and commitment therapy (ACT), on religiously oriented obsessive and compulsive disorder (OCD).
- Trial name
- NCT06647589
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Schizophrenia, Treatment Resistant Depression (TRD)
Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment
The disruption of immune system is a key candidate in the pathogenesis of psychiatric disorders, especially those resistant to traditional treatments.
- Conditions
- Schizophrenia, Treatment Resistant Depression (TRD), Bipolar Disorder (BD), Catatonia
- Trial name
- BIO-INM (NCT07741981)
- Testing
- Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Centre Hospitalier St Anne
Obsessive-Compulsive Disorder (OCD)
OCD Summer Treatment Program for Adolescents in Iceland
The aim of the study is to examine the effectiveness of OCD treatment delivered in a group format for adolescents during a two week intensive summer treatment program.
- Trial name
- OCDtreatment (NCT07465354)
- Testing
- Intensive cognitive-behavioral treatment with exposure / response prevention
- Where
- Iceland
- Volunteers
- 70 people
- Sponsor
- University of Iceland
Obsessive Compulsive Disorder (OCD)
Transcutaneous Electrical Acupoint Stimulation Combined With Exposure and Response Prevention in the Treatment of Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial
Obsessive-compulsive disorder is a chronic and disabling mental disorder. Among them, 40-60% of obsessive-compulsive disorder patients do not respond to the current first-line drug treatment and/or psychological therapy.
- Trial name
- NCT07811778
- Testing
- Exposure and Response Prevention, Active Transcutaneous Acupoint Electrical Stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Mental Health Center
Obsessive Compulsive Disorder (OCD)
Bergen Four-Day Treatment (B4DT) for Obsessive-Compulsive Disorder
The aim of this study is to expand access to Bergen Four-Day Treatment (B4DT) in Finland and to integrate it into psychiatric care pathways at Tampere University Hospital (TAYS).
- Trial name
- NCT07644130
- Testing
- Bergen Four-Day Treatment (B4DT)
- Where
- Finland
- Volunteers
- 65 people
- Sponsor
- Tampere University Hospital
Depression, OCD
Accelerated TMS for Depression and OCD
Repetitive transcranial magnetic stimulation (rTMS) is a FDA-approved treatment for depression and Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT04982757
- Testing
- MagVenture MagPro System with Brainsight neuronavigation device
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Weill Medical College of Cornell University
OCD
Light Therapy for Obsessive-compulsive Disorder (OCD)
The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later).
- Trial name
- KLTO (NCT06720090)
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine