Clinical trials: OHS
Schizophrenia and Other Psychotic Disorders, Healthy Adult
Dysfunction of Respiratory Enzymes in Adults With Mental Illness (DREAM)
This study tested whether intravenous methylene blue changes brain activity during a working-memory task differently in adults with schizophrenia taking stable antipsychotic medication and healthy volunteers.
- Trial name
- DREAM (NCT07866833)
- Testing
- Methylene Blue
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College London
Bronchial Asthma, Bronchiectasis
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis.
- Conditions
- Bronchial Asthma, Bronchiectasis, ILD, COPD
- Trial name
- NCT07060079
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University College, London
Obesity Hypoventilation Syndrome (OHS)
Pathophysiology of Hypoventilation in Obesity and Effects of Bariatric Intervention
Breathing is impacted by obesity. Early changes are characterised by significant breathing abnormalities during sleep (a condition called sleep disordered breathing, the most common of which is obstructive sleep apnoea).
- Trial name
- PHOEBI (NCT04025528)
- Testing
- Bariatric Surgery
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Obesity, COPD, OHS
Hypoxia in Flight Simulation in Obese Patients
The purpose of this pilot study is to determine whether obese adults,obese (BMI>30 kg/m2) with obesity hypoventilation or obese COPD-patients do undergo oxygen desaturation under flight simulation and if the hypoxic altitude…
- Trial name
- NCT02636465
- Testing
- flight simulationin obese healthy adults or obese patients with or without COPD, OHS
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Intermittent Positive-pressure Ventilation, Respiratory Physiological Phenomena
Impact of Non-intentional Leaks on Noninvasive Ventilation
The investigators hypothesized that increasing non intentional leaks could increase work of breathing and could lead to patient/non-invasive ventilation (NIV) asynchrony.
- Trial name
- NIV-Leaks (NCT00983411)
- Testing
- Non intentional leaks during non invasive ventilation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- AGIR à Dom
Patients Treated With VaserShape MC1
Protocol To Evaluate Patient Measurements After Ultrasonic Treatment
Patients enrolled in this study will come from the Investigator's patient population and be ordinarily suitable for treatment using the MC1 device.
- Trial name
- NCT01373827
- Testing
- VASERShape MC1
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Sound Surgical Technologies, LLC.
Ocular Histoplasmosis Syndrome
Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization in Ocular Histoplasmosis Syndrome
The purpose of this study is to evaluate the safety and effectiveness of intravitreal ranibizumab (Lucentis) in patients with fluid and blood leakage in their eyes due to ocular histoplasmosis.
- Trial name
- IVL for OHS (NCT00955630)
- Testing
- ranibizumab
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Retina Associates of Kentucky
Females Scheduled to be Treated Using the MC1.
Protocol To Evaluate Patient Measurements After Ultrasonic Treatment
The objective of this study is to observe body contour changes following treatment using the MC1 device.
- Trial name
- NCT01260298
- Testing
- MC1 Ultrasonic Device
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sound Surgical Technologies, LLC.