Clinical trials: OSAS
Obstructive Sleep Apnea, Fat Disorder
Metabolism and Sleep Apnea Treatment
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism.
- Trial name
- MaST (NCT05539716)
- Testing
- PAP Therapy, Lifestyle Counseling Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Sleep Apnea, Obstructive
Effect of OSA on RV Heamodynamics and Function
Correlation of severity of obstructive sleep apnea and function of the right ventricle by means of 2D echocardiography and cardiac MRI
- Trial name
- NCT03267667
- Testing
- 2D Echocardiography and cardiac MRI
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obstructive Sleep Apnea, Insulin Resistance
Exploring the Role of Adipocyte Fatty Acid Binding Protein in the Association of Obstructive Sleep Apnea and Metabolic Dysfunction
Adipocyte fatty acid binding protein (A-FABP) is a member of the FABP super family, is abundant in adipocytes and macrophages. Regulatory functions of A-FABP in lipid and glucose metabolism have been described, and it is…
- Conditions
- Obstructive Sleep Apnea, Insulin Resistance, Metabolic Syndrome, Inflammation
- Trial name
- NCT01173432
- Testing
- continuous positive airway pressure
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sleep Apnea Syndromes
Efficiency of a Phone Coaching for Sleep Apnea Hypopnea Syndrome Patients
Background: Continuous Positive Airway Pressure (CPAP) remains the reference treatment for moderate to severe forms of the Sleep Apnea/Hypopnea Syndrome (SAHS).
- Trial name
- NCT02435355
- Testing
- telephone-based counselling
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Sadir Association
Obstructive Sleep Apnea Syndrome
Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome
The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration.
- Trial name
- IRM SAOS (NCT05147649)
- Testing
- functional magnetic resonance imaging
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Obstructive Sleep Apnea, Obstructive Sleep Apnea-hypopnea
Updating Deep Learning Algorithms for OSA Monitoring
The objective is to enhance the reliability of the algorithm to match that of Level 1 polysomnography by leveraging the diverse data obtained from Level 1 polysomnography to refine the deep learning algorithm.
- Trial name
- NCT06522815
- Testing
- CART-I plus, Polysomnography
- Where
- South Korea
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Sky Labs
Sleep Apnea, Obstructive
Effect of Adenotonsillectomy on Quality of Life in Children With Mild Obstructive Sleep Apnea
In children, enlarged adenoids and/or tonsils are the most common cause of obstructive sleep apnea (OSA), which is temporary blockage of breathing during sleep.
- Trial name
- NCT01539278
- Testing
- Adenotonsillectomy, Observation alone / no intervention
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Obstructive Sleep Apnea
Potential Mechanism of Exercise Impairment in OSA
Obstructive sleep apnea (OSA) is a common disorder with major cardiovascular sequelae. A recent study confirmed that OSA is associated with impaired exercise capacity and increasing OSA severity predicts worsening exercise…
- Trial name
- NCT02505594
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea
Alesis OSA-1 Obstructive Sleep Apnea Treatment
The goal of randomized clinical trial is to determine if the Alesis OSA-1 low laser light therapy device can reduce apnea-hypopnea index scores and treat sleep apnea in adult participants over the age of 18 who are diagnosed with…
- Trial name
- OSA (NCT06949969)
- Testing
- OSA LLLT treatment device
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Photonica USA, LLC
Adenotonsillar Hypertrophy, Obstructive Sleep Apnea
Ketorolac on Postoperative Pain Reduction in Pediatric Patients with Adenotonsillectomy
Postoperative pain management in the pediatric patient undergoing tonsillectomy is challenging. Despite being used in many procedures for postoperative pain management, perioperative ketorolac usage in pediatric tonsillectomy…
- Conditions
- Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Sleep-Disordered Breathing, Acute Post Operative Pain
- Trial name
- NCT05074056
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Organic Pediatric Obstructive Sleep Apnea
Nasal Expiratory Positive Airway Pressure for the Treatment of Pediatric Obstructive Sleep Apnea Syndrome
This study will evaluate effectiveness and adherence of the nasal expiratory positive airway pressure (NEPAP) device as an an alternate therapy for children with Obstructive Sleep Apnea Syndrome (OSAS).
- Trial name
- NCT01768065
- Testing
- Nasal Expiratory Positive Airway Pressure Device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Hypertension, Chronic Kidneys Disease
Nocturnal Blood Pressure and Hypertension - Central and Peripheral 24-h Blood Pressure.
A new study have shown that high night time blood pressure (BP) and/or non-dipping (lack of fall in BP during night time) is a strong predictor for the risk of cardiovascular disease and mortality in patients with hypertension.
- Conditions
- Hypertension, Chronic Kidneys Disease, Obstructive Sleep Apnea
- Trial name
- HOSA (NCT02078765)
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Erling Bjerregaard Pedersen
Obstructive Sleep Apnea, Atrial Fibrillation
Effective Conversion of Individuals at Risk
This study aims to guide participants in recognizing their OSA (obstructive sleep apnea) and AFib (atrial fibrillation) symptoms, realizing what medical conditions can cause these symptoms (if any) and inform the participants on…
- Trial name
- NCT05112757
- Testing
- Smartphone application use
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Obstructive Sleep Apnea
Diaphragmatic Function and Respiratory Drive in OSA and COPD
This cross-sectional observational study aims to assess the diaphragmatic morphofunction and respiratory drive characteristics among patients with obstructive sleep apnea (OSA), chronic obstructive pulmonary disease (COPD)…
- Trial name
- NCT07003399
- Testing
- Diaphragmatic Ultrasound and EMG Assessment
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Obstructive Sleep Apnea (OSA), Insomnia
Validating the Use of a Subjectively Reported Sleep Vital Sign
Sleep disorders are commonly under-recognized in the primary care setting and available screening tools are often are limited. The study inestigators hypothesize that the use of a novel subjective sleep vital sign (VS) will…
- Conditions
- Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder
- Trial name
- SVS (NCT03018912)
- Testing
- Sleep VS
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pheochromocytoma, Obstructive Sleep Apnea
Metanephrines in Obstructive Sleep Apnoea
Although most patients have essential (unexplained) hypertension, some patients have a treatable underlying condition. One such condition is phaeochromocytoma, a tumour that produces excessive stress hormones.
- Conditions
- Pheochromocytoma, Obstructive Sleep Apnea, Catecholamine; Secretion
- Trial name
- NCT05053685
- Testing
- Measurement of Urine and plasma metanephrines
- Where
- Singapore
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Obstructive Sleep Apnea
Analyze Sleep Stages by Portable ECG Device
Sleep is a fundamental need for human and is associated with the working performance and the disease occurrence. Furthermore, the amount of people with sleep disorder or apnea increased largely.
- Trial name
- NCT02765958
- Testing
- portable ECG devise
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Obstructive Sleep Apnea
Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device
The study is designed to assess the usability of a novel CPAP human interface compared to a traditional nasal mask. Human subjects will interact with two different CPAP interfaces including a traditional CPAP mask and the 2nd…
- Trial name
- NCT05570747
- Testing
- Usability
- Where
- 3 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bleep, LLC
Obstructive Sleep Apnea
Unveiling the Neural Mechanisms of 5-HT7 in Sleep Apnea Induced by Arousal Dysregulation
Obstructive sleep apnea (OSA), recognized as a highly prevalent sleep breathing disorder with severe complications, features a complex etiology.
- Trial name
- NCT06608888
- Testing
- MRI
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Type 2 Diabetes, Obstructive Sleep Apnoea
EndoBarrier in Obstructive Sleep Apnoea Study
Obstructive sleep apnoea (OSA) is a common condition in which the upper airways (windpipe) collapse repeatedly during sleep, blocking the flow of air into the lungs.
- Conditions
- Type 2 Diabetes, Obstructive Sleep Apnoea, Obesity
- Trial name
- End-OSA (NCT06376305)
- Testing
- EndoBarrier
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dr Bob Ryder