Clinical trials: Obese Individuals
Obesity, Cardiovascular Risk Factors
Effects of Soy Based Dietary Supplements on Cardiometabolic Risk Factors.
This study will test the effect of both Luna Rich X© and Reliv Now© against placebo pills or powder (control) on blood lipids. It will also explore the potential effects of these dietary supplements on inflammation markers and…
- Trial name
- NCT02490683
- Testing
- Luna Rich X, Reliv Now
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loma Linda University
Obesity
Impact of Whey and Soy Protein Ingestion in Conjunction With Energy Restriction in Overweight/Obese Individuals
It is known that dieting (restricted energy intake) without resistance training leads to a reduced metabolic rate, and the loss of both fat and muscle mass.
- Trial name
- NCT01530646
- Testing
- Weight loss, Soy, Whey
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- McMaster University
Obesity, Aging
Appetite Regulation in Older-Aged Obese Individuals
This study plans to learn more about how age and weight impact appetite and food intake. Specifically, this study is being done to see whether age and obesity impact appetite and the brain's response to food.
- Trial name
- NCT02721303
- Testing
- 3-day diet Run-in, fMRI, Intravenous catheter placed for blood draws
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity
AVocAdo Extract to Improve gLycemia in Individuals With Obesity (AVAIL)
This two-arm, double blind, randomized clinical trial will compare the effect of an avocado extract, compared to placebo, on cardiometabolic outcomes in adults with obesity.
- Trial name
- NCT04763473
- Testing
- Avocado extract
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Obesity
Cannabis for Obesity Trial
The goal of this study is to determine the initial efficacy of once daily oral cannabis for weight loss in obese individuals.
- Trial name
- NCT06137365
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Joshua A. Lile, Ph.D.
Metabolically Healthy Obesity
Brown Fat Tissue Related Hormone Levels in Metabolically Healthy and Unhealthy Obese Individuals
There are two types of adipose tissue in humans, white and brown adipose tissue. While the main task of white adipose tissue is energy storage, the main task of brown adipose tissue is energy expenditure.
- Trial name
- NCT05232695
- Testing
- metabolically healthy obese
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Diabetes Mellitus
Plantar Pain, Balance and Foot Function in Individuals With Diabetes Mellitus
Diabetes Mellitus (DM) and increase of body mass index (BMI) are two one of the most common risk factors for plantar pain and related disability.
- Trial name
- NCT04444375
- Testing
- balance test
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Suleyman Demirel University
Wearable Electronic Device
EAT: A Reliable Eating Assessment Technology for Free-living Individuals
This study utilizes a small, privacy-conscious wearable device intended to monitor human behaviors. The device is worn around the neck, capturing the wearer's head and upper torso within its field of view, and records color…
- Trial name
- EAT (NCT06118528)
- Testing
- Blur Obfuscation, Cartoon Obfuscation, Edge Obfuscation
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Overweight, Obese
Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management
Currently in the United States about 97 million adults are considered obese, accounting for about 33% of the American adult population (compared to 22.9% in 1988).
- Trial name
- NCT02129608
- Testing
- LLLT, Lorcaserin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Liver Diseases
Magnetic Resonance Spectroscopy (MRS) Validation Study in Individuals With Nonalcoholic Fatty Liver Disease (NAFLD)
The purpose of this study is to see how effective the investigators' optimized magnetic resonance spectroscopy (MRS) sequence in quantifying hepatic triglyceride content (HTGC) to enhance MRS as a diagnostic tool in non-alcohol…
- Trial name
- NAFLD (NCT00940537)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity and Overweight
Metabolic Phenotyping for Personalized Obesity Therapy
This study aims to develop a simple, clinically applicable method for metabolic phenotyping to personalize obesity therapy in morbidly obese individuals.
- Trial name
- NCT06874270
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- University Hospital Schleswig-Holstein
Obesity, Obesity; Endocrine
Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study
Regular exercise is a cornerstone in the prevention and the management of cardio-metabolic risk factors. Some of the beneficial effect of exercise training occurs through metabolic flexibility' enhancement.
- Conditions
- Obesity, Obesity; Endocrine, Insulin Sensitivity, Exercise
- Trial name
- i-FLEX (NCT03527446)
- Testing
- Sprint Interval Training
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Non-Alcoholic Fatty Liver Disease, Obesity
Sulforaphane Supplementation Study
Non-alcoholic fatty liver disease (NAFLD) is increasing in the population, and is associated with heart disease and diabetes. At present there are no licensed drugs for treatment of NAFLD, therefore changes in diet and increased…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Metabolic Syndrome
- Trial name
- FAMOUS (NCT04364360)
- Testing
- Sulforaphane extract
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Obesity, Morbid, Bariatric Surgery Candidate
Adipose Tissue Inflammation in Individuals Undergoing Bariatric Surgery
A growing body of work done over the past few decades has established that adipose tissue as an active endocrine organ which secretes a wide range of metabolic and immunological factors collectively called "adipokines (1)."…
- Trial name
- NCT03419273
- Testing
- bariatric surgery
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity
Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals
Background: Roflumilast is a drug used to treat chronic obstructive pulmonary disease (COPD). It is designed to help reduce lung inflammation.
- Trial name
- NCT01862029
- Testing
- Roflumilast
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity
Impact of Probiotics on Weight Control and Body Composition in Overweight and Obese Individuals
The aim of the study is to evaluate the potential of probiotics on weight management. It is hypothesized that the consumption of 1 capsule of probiotics daily will modulate the intestinal gut microbiota thereby reducing body…
- Trial name
- NCT02893943
- Testing
- Probiotics
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity
Trigona Honey and Intestinal Microbiota Among Obese People
Objective : Nutrition intervention is one of the approaches to deal with obesity. Natural honey with its polyphenol component has an impact on the intestinal microbiota and lipid profile.
- Trial name
- NCT04974450
- Testing
- Trigona honey, control
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University