Clinical trials: Obese Subjects
Obese Adolescents, Mental Health
Co-creating School Community Intervention Program on Physical Activity to Increase Health Equity in Children and Adolescents
The goal of this observational and interventional study is to understand whether environmental and behavioral interventions can improve physical activity and health outcomes in children aged 12-16 years attending VDU Atžalynas…
- Trial name
- Connection (NCT07120516)
- Where
- Lithuania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sandra Andrusaityte
Obese Patients With Bariatric Surgery, Obese Patients (BMI ≥ 30 kg/m²)
Interventions for Weight Regain After Bariatric Surgery
Study Objective: The aim of this study is to evaluate the effects of revisional bariatric surgery (RBS), very low-calorie ketogenic diet (VLCKD), and intermittent fasting (IF) on nutritional habits and clinical outcomes…
- Conditions
- Obese Patients With Bariatric Surgery, Obese Patients (BMI ≥ 30 kg/m²), Weight Regain Post Bariatric Surgery, Revisional Bariatric Surgery
- Trial name
- NCT06963437
- Testing
- Diet, Ketogenic diet, Fasting
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Medipol University
Obese or Overweight Healthy Volunteers
Clinical Study to Assess the Safety and Efficacy of ACV Moringa Effervescent Tablet Intake on Weight Management in Overweight and Class I Obese Study Participants
A Randomized, Double-Blind, Placebo-Controlled, Two-Arm, Single-Centre, Clinical Study to Evaluate the Safety and Efficacy of Intake of ACV Moringa on the Degree of Weight Change in Overweight and Class I Obese Study Participants
- Trial name
- NCT07098624
- Testing
- ACV Moringa Effervescent Tablets 4.3 g
- Volunteers
- 66 people
- Sponsor
- NovoBliss Research Pvt Ltd
Obese Children and Adolescents
Digital Wellness Nurse - FIT Families: Virtual Family Intervention for Adolescent Obesity
The purpose of the research is to evaluate the digital wellness nurse (DWN) app to find out if it is helpful in delivering the FIT Families intervention. The study is sponsored by the National Institutes of Health (NIH).
- Trial name
- DWN-FIT (NCT07087808)
- Testing
- Digital Wellness Nurse - FIT Families
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Machine and Human Interaction
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Driving Pressure, Positive End-expiratory Pressure
Driving Pressure-guided Positive End-expiratory Pressure to Prevent Postoperative Atelectasis in Obese Children: a Prospective, Randomized Controlled Clinical Trial
At present, the use of lung protective ventilation strategies in children is mainly based on adult and intensive care unit data.
- Conditions
- Driving Pressure, Positive End-expiratory Pressure, Postoperative Atelectasis, Obese
- Trial name
- NCT06471491
- Testing
- Driving pressure-guided positive end-expiratory pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Henan Provincial People's Hospital
Sleep Apnea Syndromes, Metabolic Syndrome
Evaluating of the Impact of a Connected and Non-intrusive Device in Improving the Screening of Sleep Apnea Syndrome and the Addressing of Potentially Pathological Patients in Hospital Environment
Diabetes, obesity and metabolic syndrome are closely linked to sleep apnea syndrome. Indeed, diabetic and/or obese patients present an increased risk of sleep apnoea syndrome (SAS), with a prevalence estimated at between 10 and…
- Conditions
- Sleep Apnea Syndromes, Metabolic Syndrome, Diabetes, Obese
- Trial name
- AMELIAS (NCT06141967)
- Testing
- WITHINGS Sleep Analyzer
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Overweight and Obese Adults, Healthy
Sex Hormones as Regulators of the Age- and Sex-dependent Benefits of Caloric Restriction
Obesity increases the risk of type 2 diabetes, cardiovascular disease, and certain cancers, primarily due to elevated abdominal fat storage.
- Trial name
- GendAge (NCT07065643)
- Testing
- Phase 1 - Maintenance Diet, Phase 2 - Weight loss diet
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Obese Children and Adolescents, Adolescent Obesity
Response of Lipid Profile to Virtual Reality Games Versus Moderate Aerobic Exercise Training in Children With Obesity
This trial is aiming to study the effect of virtual reality video gaming in comparison with moderate intensity aerobic exercises on lipid profile in children with Obesity
- Conditions
- Obese Children and Adolescents, Adolescent Obesity, Obesity, Body Mass Index
- Trial name
- NCT07073651
- Testing
- Moderate Intensity Aerobic Exercise, Dietary Advices, Virtual reality games exercise
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Badr University
Obese Patients (BMI ≥ 30 kg/m²), Obese Patients
Modifications to Gastric Sleeve: Implications for GRED and Quality of Life
This is a prospective randomized clinical trial evaluating the impact of antrum and fundus calibration during laparoscopic vertical gastrectomy (VG) on postoperative gastroesophageal reflux disease (GERD), quality of life, and…
- Conditions
- Obese Patients (BMI ≥ 30 kg/m²), Obese Patients, Obese Patients With Bariatric Surgery, Obese With Comorbidities
- Trial name
- NCT07070908
- Testing
- Antrum calibration, Fudus calibration, No antrum calibration
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Laparoscopic Bariatric Surgeries, Hypoxemia
Intra-Operative Modified Ventilator Mechanical Power in Laparoscopic Bariatric Surgeries
To compare the effects of two levels of mechanical power on the incidence of post-operative hypoxemia in morbid obese patients undergoing laparoscopic bariatric surgeries.
- Conditions
- Laparoscopic Bariatric Surgeries, Hypoxemia, Obese Patients
- Trial name
- NCT07065370
- Testing
- Group I ( volume-controlled ventilation with tidal volume 6-8ml/kg (predicted body weight) with respiratory rate 12-14 cycle/minute., Group II: (volume-controlled ventilation with tidal volume 6-8ml/kg )
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Overweight or Obese
Phase II Study of THDBH120 Injection in Overweight or Obese Subjects
To assess the efficacy and safety of THDBH120 injection compared with placebo in weight reduction in overweight or obese subjects after 26 weeks of treatment.
- Trial name
- NCT07036601
- Testing
- THDBH120 injection
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Tonghua Dongbao Pharmaceutical Co.,Ltd
Obesity, Overweight
The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults
The present study is a 100-participant randomized controlled 2-arm parallel trial that employs a metagenomic approach to examine how 8 weeks of supervised moderate-intensity treadmill walking exercise (MWE) for 30-45 min 3…
- Conditions
- Obesity, Overweight, Overweight and Obesity, PreDiabetes
- Trial name
- NCT04931836
- Testing
- Physical Activity Intervention
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Minnesota
Diabetes Mellitus Type 2, Obese Diabetics
Remission of Type 2 Diabetes With Lifestyle Intervention
The goal of this clinical trial is to achieve diabetes type 2 (DM2) remission using intensive lifestyle intervention. The main questions it aims to answer are: Does intensive lifestyle intervention (including Mediterranean diet…
- Trial name
- REMeDI2ME (NCT07017127)
- Testing
- Mediterranean diet, Physical activity intervention, Psychological intervention
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University of Split, School of Medicine
Obese Patients, Tobacco Use
Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux
The veteran population is at increased risk for EAC and its precursor lesion, Barrett's esophagus (BE), due to increased prevalence of disease risk factors compared to the general population.
- Conditions
- Obese Patients, Tobacco Use, Veterans, Family History of Esophageal Cancer
- Trial name
- NCT06746623
- Testing
- Enrolled participants will complete Esocheck/Esoguard and diagnostic upper endoscopy.
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Louis Stokes VA Medical Center
Menopausal, Obese Patients
Effect of Pilates Exercises on Menopausal Symptoms
Menopause, a significant transition in a woman's life characterized by the cessation of menstruation and a decline in ovarian function, leads to reduced levels of estrogen and progesterone.
- Conditions
- Menopausal, Obese Patients, Pilates Exercise, Quality of Life and Menopause
- Trial name
- NCT06996743
- Testing
- reformer pilates group, Mat pilates group, Lifestyle change group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Batman University
Obese Patients
Impact of Thoracic Duct Ligation on Postoperative Weight Reduction in Obese Patients Receiving Minimally Invasive Lung Surgery: A Clinical Investigation
This clinical trial aims to investigate whether thoracic duct ligation (TDL) can improve obesity and lipid metabolism. The primary questions it seeks to answer are: Whether thoracic duct ligation can improve BMI and lipid…
- Trial name
- NCT06995599
- Testing
- Thoracic Duct Ligation (TDL)
- Volunteers
- 16 people
- Sponsor
- Yongxin Zhou
Overweight or Obese, Obesity and Overweight
A Trial With EMP16 in Preparation for Late Phase Studies
The goal of this clinical trial is to explore the impact of dietary fibre supplement in the form of Vi-Siblin® S (ispaghula seed coats), together with advice on proper healthy diet, on tolerability during dose-escalation of EMP16…
- Trial name
- POEM (NCT06993428)
- Testing
- EMP16-02 120 mg orlistat/40 mg acarbose, Alli® 60 mg, Vi-Siblin® S
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Empros Pharma AB
Obese
Dynamo: a Tailored Lifestyle Promotion Intervention Among Pediatric Patients With Cardiometabolic Risk Factors
The Dyn@mo lifestyle intervention (CHU Sainte-Justine, Quebec, Canada) targets children and adolescents aged 6 to 17 years old with cardiometabolic risk factors, such as obesity, hypertension, disorders in glucose regulation or…
- Trial name
- CIRCUIT (NCT01736748)
- Testing
- Sensor based PA intervention, Traditional PA counseling
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Justine's Hospital
Mediterranean Diet, Overweight or Obese Adults
ENERGY2MOB STUDY: OBESITY MANAGEMENT IN BERGUEDÀ
Background: Obesity is a prevalent multifactorial disease worldwide and has become a significant public health concern. The latest data from the 2022 Catalonia Health Survey show that 56.2% of men and 43.7% of women are…
- Conditions
- Mediterranean Diet, Overweight or Obese Adults, Exercise Therapy, Cardiovascular Diseases
- Trial name
- ENERGY2MOB (NCT06988904)
- Testing
- Energy2MOB
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina