Clinical trials: Obese Subjects
Type 2 Diabetes, Obese
The Effects of the GOLO for Life® Plan With Release Supplement on Glycemic Control and Weight in Overweight and Obese Adults With Prediabetes or Type 2 Diabetes
The objective of this study is to investigate the efficacy and safety of the GOLO for Life® Plan (G4LP) and Release supplementation on glycemic control and weight in overweight and obese adults with Prediabetes or Type 2…
- Conditions
- Type 2 Diabetes, Obese, Overweight, Prediabetes
- Trial name
- NCT05844644
- Testing
- Release
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Golo
Obese Impaired Glucose Tolerance, Newly Diagnosed Obese Type 2 Diabetic Patients
Characterization and Mechanism Research of the Pre-disease State of Obese Type 2 Diabetes Mellitus
Establish a comprehensive evaluation system for the progression of obese impaired glucose tolerance (IGT) to type 2 diabetes mellitus (T2DM) through cross-sectional studies; Constructing and validating a T2DM risk prediction…
- Trial name
- NCT06495814
- Testing
- 1/bag of Jinlida granules, 3 times/day, taken with hot water.
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Fengmei Lian
Overweight, Healthy Volunteers
A Research Study Looking at the Safety of Multiple Doses of ZP8396 and How it Works in the Body of Healthy Participants
The trial is a single-centre, randomised and double-blind within cohorts, placebo-controlled, sequential multiple ascending dose trial in normal weight and overweight but otherwise healthy subjects randomised to subcutaneous…
- Conditions
- Overweight, Healthy Volunteers, Obese
- Trial name
- NCT05613387
- Testing
- ZP8396
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Zealand Pharma
Inflammatory Disease, Aging Problems
Umbilical Cord Mesenchymal Stem Cell for Aging-related Low-grade Inflammation
The goal of this single-group, open-label, phase I/II clinical trial is to evaluate the safety and efficacy of the transplantation of umbilical cord mesenchymal stem cells in aging-related low-grade inflammation patients'…
- Conditions
- Inflammatory Disease, Aging Problems, Obese, Lipid Metabolism Disorders
- Trial name
- NCT06448052
- Testing
- umbilical cord mesenchymal stem cell
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- Nguyen Ton Ngoc Huynh
Type 2 Diabetes Mellitus in Obese, Type 2 Diabetes
LCMD for Type 2 Diabetes Remission: Evaluation of Effectiveness and Exploration of Individual Differences
Type 2 diabetes (T2DM) has become a major public health problem. Achieving remission (HbA1c<6.5% without glucose-lowering medications) has recently become a new treatment goal.
- Trial name
- LCMD (NCT06442150)
- Testing
- Low-Calorie Medicine Diet, Low-Calorie Diet
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Obese Women
Balanced Nutritional Diet Intervention Among Obese Women
Food intake along with the gene are important factors that influence human nutrition status and health. Indonesia has a balanced nutrition diet guide for ideal food consumption.
- Trial name
- NCT06442202
- Testing
- Balanced Nutritional Diet, Nutritional Education
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Padjadjaran
Healthy, Normal Weight
Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts
The researchers will investigate blood and fecal responses in qualified study participants after eating walnuts for 4 weeks compared to not eating walnuts for 4 weeks.
- Conditions
- Healthy, Normal Weight, Overweight, Obese
- Trial name
- NCT04307628
- Testing
- Walnut, Nut-Free
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Overweight, Obese
Post-delivery Maternal-offspring Obesity and Metabolic Risk After a Prepregnancy Weight-loss Intervention
The goal of PrepareD is to examine whether the prepregnancy weight-loss intervention administered during the Prepare trial [NCT02346162] has an influence in the postnatal period.
- Conditions
- Overweight, Obese, Metabolic Disorders, Postpartum
- Trial name
- PrepareD (NCT06067126)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Kaiser Permanente
Obese, Headache
Relation Between Forward Head Posture and Incidence of Headache in Obese Adults
Cross sectional study to detect relation between forward head posture and headache. We will take information from the patient about: Detailed history of patient Forward head posture by using mobile application Headache disability…
- Conditions
- Obese, Headache, Neck Pain
- Trial name
- NCT06383429
- Testing
- forward head posture by using mobile application. And patients will fill out headache disability index.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ahram Canadian University
Type 2 Diabetes Mellitus in Obese, Obesity
A Study to Assess 11 Beta-hydroxysteroid Dehydrogenase Type 1 Inhibition in Adipose Tissue by SPI-62
This will be an exploratory, open-label study of 11β-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibition by SPI-62 in obese subjects with type 2 diabetes mellitus (T2DM)
- Conditions
- Type 2 Diabetes Mellitus in Obese, Obesity, Type2Diabetes
- Trial name
- NCT05409027
- Testing
- SPI-62, Cortisone-d8
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sparrow Pharmaceuticals
Intermittent Fasting, Weight Loss
The Effectiveness of Intermittent Fasting and Behavioral Economics Intervention on Weight Control in Obese Patients
This study is a parallel randomized controlled trial (RCT). To determine the effect of intermittent fasting, intermittent fasting with behavioral economics, and intensive lifestyle modification on nutritional status; the…
- Conditions
- Intermittent Fasting, Weight Loss, Behavioral Economic, Obese
- Trial name
- NCT06261229
- Testing
- Intermittent fasting, Intermittent fasting + Behavioral economic, Intensive Lifestyle Modification
- Where
- Thailand
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Obesity, Obesity, Abdominal
Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Type 2 Diabetes Patients (DELI_Diab Study)
The current study aim was to conduct placebo-controlled randomize clinical trial to assess the short-term efficacy and safety of postbiotics as an adjunction to the standard anti-diabetic therapy on insulin resistance, glycemic…
- Conditions
- Obesity, Obesity, Abdominal, Insulin Resistance, Insulin Sensitivity
- Trial name
- NCT05770076
- Testing
- Probiotic lysate (postbiotic and metabiotic)
- Where
- 4 sites in Ukraine
- Volunteers
- 55 people
- Sponsor
- Bogomolets National Medical University
Obesity, Diabetes Mellitus Type 2 in Obese
Deciphering the Role of Incretin Hormones in Weight Loss-induced Remission of Type 2 Diabetes (DIABeat)
The goal of this mechanistic study is to investigate the role of incretin hormones on weight loss-induced type 2 diabetes remission.
- Trial name
- DiabEATit (NCT06333132)
- Testing
- Weight loss-induced Diabetes Remission
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Metformin for Obese Pregnant Women
Maternal and Fetal Outcome With Metformin Therapy for Obese Pregnant Women .
To evaluate the role of metformin in pregnant women with obesity (BMI above 30) , on maternal and infant outcome.
- Trial name
- NCT05554679
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Assiut University
Obese, Overweight
The Effects of the GOLO for Life® Plan and Release Supplement on Weight Management in Overweight and Obese Adults
The objective of this study is to investigate the efficacy and safety of the GOLO for Life® Plan (G4LP) and Release supplementation on weight loss, body composition, and cardiometabolic parameters in overweight and obese adults.
- Trial name
- NCT05844631
- Testing
- Release
- Where
- 2 sites in Canada
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Golo
CKD, Diabetic Kidney Disease
Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy
This randomized study evaluates the effect of subcutaneous semaglutide /in combination with lifestyle counseling in patients with type 2 diabetes mellitus (T2DM), overweight/obesity, and stage 4-5 chronic kidney disease (CKD) or…
- Conditions
- CKD, Diabetic Kidney Disease, Type 2 Diabetes Mellitus in Obese, Obesity
- Trial name
- RAISE-KT (NCT04741074)
- Testing
- Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Geisinger Clinic
Diabetes Mellitus Type 2, Diabetes Mellitus Type 2 in Obese
The Effects of Nutritional Intervention on Health Parameters in Participants With Type 2 Diabetes Mellitus
The goal of this clinical trial is to evaluate the effects of nutritional intervention on anthropometric, biochemical and cardiovascular parameters in participants with type 2 diabetes mellitus.
- Conditions
- Diabetes Mellitus Type 2, Diabetes Mellitus Type 2 in Obese, Diabetes, Diabetes Mellitus Non-insulin-dependent
- Trial name
- NCT06235762
- Testing
- Nutritional Intervention
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Sao Jose do Rio Preto Medical School
Midlife Obese Adults With Cognitive Decline
Weight Reduction and Cognitive Health: Pilot Study Testing a Prolonged Testing Prolonged Fasting Among Obese, Stressed Mid-life Adults
Using a randomized controlled trial (RCT) design, we will test feasibility and outcomes following an remotely delivered, nationwide 8-week prolonged nightly fasting (PNF) intervention compared to an health education control (HEC)…
- Trial name
- GetSmart (NCT05388318)
- Testing
- Prolonged nightly fasting, Health Education Control
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obese Women With PCOS
EFFECT OF CRYOLIPOLYSIS ON HORMONAL PROFILE AND MENSTRUAL REGULARITYIN OBESE WITH PCOS
The effecting study to determine the impact of cryolipolysis on obese women with pcos
- Trial name
- NCT06226701
- Testing
- Cryolipolysis device
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sabrin Mohamed Taha Abdelwahab
Type 2 Diabetes Mellitus in Obese, Cryotherapy Effect
Effect of Cryolipolysis on Insulin Resistance
Diabetes mellitus (DM) is a complex chronic illness associated with a state of high blood glucose level, or hyperglycemia, occurring from deficiencies in insulin secretion, action, or both.
- Trial name
- NCT06223490
- Testing
- Cryolipolysis
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University