Clinical trials: Obese Women
Gestational Weight Gain, Overweight and Obesity
Healthy Gestational Weight Gain Programme
This study aims to evaluate the efficacy of a multi-component lifestyle interventions during pregnancy on promoting appropriate gestational weight gain, preventing GDM, and improving pregnancy, delivery, and neonatal outcomes…
- Trial name
- NCT06370533
- Testing
- behavioral interventions
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking University
Obesity
Taurine Supplementation and Training Effects on Energy Metabolism, Inflammation and Oxidative Stress in Obese Women
Taurine supplementation researches have increased due to its antioxidant and anti-inflammatory actions, and its ability to modulate lipid metabolism by stimulating the expression of proteins that regulates mitochondrial…
- Trial name
- Taurine (NCT04279600)
- Testing
- Taurine, Exercise training
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
COVID-19, Chronic Heart Failure
Analysis of Health Status of Сomorbid Adult Patients With COVID-19 Hospitalised in Fourth Wave of SARS-CoV-2 Infection
Depersonalized multi-centered registry initiated to analyze dynamics of non-infectious diseases after SARS-CoV-2 infection in population of Eurasian adult patients.
- Conditions
- COVID-19, Chronic Heart Failure, Diabetes Mellitus, Chronic Kidney Diseases
- Trial name
- ACTIV4 (NCT05226416)
- Where
- Russia
- Volunteers
- 3,554 people
- Sponsor
- Eurasian Association of Therapists
Menopause, Type 2 Diabetes
Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Overweight/Obesity and Impaired Glucose Homeostasis
The overall aim is to investigate the hypothesis that restoring E2 levels through MHT improves glucose and energy homeostasis and potentiates the beneficial effects of GLP-1RA in early postmenopausal women with pre- or existing…
- Trial name
- DECLARED-CT (NCT06715514)
- Testing
- GLP-1 Receptor Agonist, Menopausal Hormone Therapy
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- Lia Bally
Polycystic Ovary Syndrome, Insulin Resistance
Insulin Resistance Before and During Pregnancy in Women With Polycystic Ovary Syndrome
The polycystic ovary syndrome (PCOS) affects about 10% of reproductive-age women. Women with PCOS are at a higher risk of gestational diabetes, which may lead to more pregnancy complications.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Insulin Sensitivity, Obesity
- Trial name
- NCT01475565
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University
Obesity & Overweight
A Single-arm Pilot Feasibility Trial of Healthy Pride
This is a one-arm pilot trial of a 12-week digitally-delivered asynchronous lifestyle intervention designed for gay men and lesbian women.
- Trial name
- NCT07690592
- Testing
- lifestyle intervention
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Stress Urinary Incontinence
Effect of Visceral vs Total Body Fat Reduction in Obese Female With Stress Urinary Incontinence
The aim of this study is to investigate the visceral fat reduction versus total body fat reduction on stress urinary incontinence in obese females.
- Trial name
- NCT05944484
- Testing
- low caloric diet, ultrasound cavitation,Kegel exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Dina Mohamed Tarek Mansour El-kasrawy
Obesity
Clinical Efficacy and Safety of a Laparoscopic Sleeve Gastrectomy in Obese Patients
This study aim to evaluate the clinical efficacy and safety after laparoscopic sleeve gastrectomy in patients with obesity. 300 patients with obesity and 49 healthy individuals with normal BMI were enrolled.
- Trial name
- NCT04548232
- Testing
- Laparoscopic sleeve gastrectomy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Obese, Vascular Diseases
Comparison of Brachial Artery Dilatation, Uterine Artery Doppler, Umbilical Artery Doppler and 1st-trimester Visceral Adipose Tissue Measurement in Obese and Normal Pregnant Women
Brachial artery flow-mediated in obese and normal-weight pregnant women dilation of uterine artery doppler and umbilical artery doppler results comparison of
- Conditions
- Obese, Vascular Diseases, Pregnancy Related, Visceral Obesity
- Trial name
- NCT04638504
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Diyarbakir Women's and Children's Diseases Hospital
Overweight and Obesity
Trial to Examine the Effect of Natural Anti- Obesity Agent (Phaseolus Vulgaris) Among Women of Lahore
This double-blind randomized placebo-controlled trial will test the hypothesis that administration of Phaseolus Vulgaris supplementation to women in Lahore, Pakistan, who are overweight will induce the weight loss (Primary…
- Trial name
- PVE-AO (NCT05451927)
- Testing
- Phaseolus Vulgaris
- Where
- 2 sites in Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hafiza Aisha Sadiqa
Obesity, Polycystic Ovary Syndrome
Heat Therapy and Cardiometabolic Health in Obese Women
Traditional medical treatments are often based on research done exclusively in males, and recent research efforts in the physiology community have highlighted critical sex differences in disease presentation and progression.
- Conditions
- Obesity, Polycystic Ovary Syndrome, Prehypertension, PreDiabetes
- Trial name
- CMH (NCT03644524)
- Testing
- Heat therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oregon
Type 2 Diabetes, Overweight
Effects of Replacing Diet Beverages With Water on Weight Maintenance of Type 2 Diabetic Obese Women: 18 Months Follow up
the present study aimed to follow up our participants in order to consider the changes in weight and anthropometric measurements after the 12-month weight maintenance as well as the total of 18 months, consisting of the…
- Conditions
- Type 2 Diabetes, Overweight, Obese
- Trial name
- NCT03726762
- Testing
- DBs at the end of the main meal + weight control program, Water at the end of the main meal+ weight control program
- Where
- Iran
- Volunteers
- 81 people
- Sponsor
- Novindiet Clinic
Insulin Resistance, Polycystic Ovary Syndrome
Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
The study aims to investigate the relationship between fasting insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) across various demographic factors, including age, sex, race/ethnicity, BMI, and polycystic…
- Conditions
- Insulin Resistance, Polycystic Ovary Syndrome, Hyperinsulinism, Obesity
- Trial name
- DAISY (NCT05950282)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ali Chappell
Obesity
NMES Plus Hypocaloric Diet: Body Composition, Cardiometabolic Markers, Irisin and Betatrophin in Women With Obesity
This randomized controlled trial evaluated whether adding localized neuromuscular electrical stimulation (NMES) to an individualized hypocaloric diet changes serum irisin and betatrophin (ANGPTL8) concentrations, body composition…
- Trial name
- NCT07675382
- Testing
- Hypocaloric Diet, Neuromuscular Electrical Stimulation (NMES)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Firat University
Hyperandrogenism, Obesity
Metabolic Profile and Adipokine Levels in Young Hyperandrogenemic Females
Assessement of basic metabolic profile and adipokine levels in young hyperandrogenemic females.
- Conditions
- Hyperandrogenism, Obesity, Metabolic Disease, Metabolic Syndrome
- Trial name
- NCT05112029
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Childhood Obesity
A Cluster Randomized Trial of the H2GO! Program
This proposal involves a collaboration with the Massachusetts Alliance of Boys and Girls Clubs. The goal is to evaluate the efficacy of youth empowerment intervention targeting sugar-sweetened beverage consumption on childhood…
- Trial name
- NCT04265794
- Testing
- H2GO!
- Where
- United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Boston University
Obesity
Perinatal Outcomes in Nutritionally Monitored Obese Pregnant Women
The aim of this prospective randomized study is the prevention of excessive weight gain in obese pregnant women. The study will compare perinatal outcomes of obese pregnant women treated in the traditional way to outcomes of…
- Trial name
- NCT00740766
- Testing
- Food diary and behavioral model
- Where
- 3 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Jamaica Hospital Medical Center
Obesity
A Study to Evaluate the Effect of the Experimental GLP-1 Drug PF-07081532 on Blood Levels of Common Birth Control Pills, and Drugs Omeprazole and Midazolam, and Effect of GLP-1 Drug Semaglutide on Midazolam Blood Levels in Healthy Adults With Weight in the Obesity Range
Two different groups of healthy volunteers will be chronically treated with GLP-1 drugs PF-07081532 or alternatively Semaglutide.
- Trial name
- NCT05671653
- Testing
- PF-07081532, Semaglutide
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pfizer
Type 2 Diabetes Mellitus, Obesity
Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes
Type 2 diabetes (T2D) in youth is increasing in prevalence in parallel with the obesity epidemic. In the US, almost half of patients with renal failure have DKD, and ≥80% have T2D.
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Bariatric Surgery Candidate, Nephropathy
- Trial name
- IMPROVE-T2D (NCT03620773)
- Testing
- Aminohippurate Sodium Inj 20%, Iohexol Inj 300 mg/mL, Vertical Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Colorado, Denver
Pre-eclampsia, Obesity
ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes
Obesity is a growing problem in East London and every other woman who enters pregnancy is obese or overweight. In addition to obesity, other metabolic risk factors such as raised lipids, high blood pressure and diabetes increase…
- Conditions
- Pre-eclampsia, Obesity, Raised Lipids, High Blood Pressure
- Trial name
- ESTEEM (NCT02218931)
- Testing
- Targeted ESTEEM diet, Non-randomised cohort
- Where
- United Kingdom
- Volunteers
- 3,442 people
- Sponsor
- Queen Mary University of London