Clinical trials: Obesity, Abdominal, open to volunteers
Ventral Hernia
Bariatric SUrgery With Mesh REpair of Ventral Hernia: a Randomized Controlled Trial
The primary objective of the study is to demonstrate that hernia recurrence (VH) repair with non absorbable mesh concomitant to Bariatric Surgery (BS) decreases the risk of VH, with or without surgical repair, during the first…
- Trial name
- BeSURE (NCT05488288)
- Testing
- Mesh repair, Suture repair
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Obesity, Postoperative Pain
Transversus Abdominis Plan Block Versus Rectus Sheath Block
The investigator aims to compare the analgesic efficacy of Transversus Abdominis Plan Block and Rectus Sheath Block which are used to prevent intraoperative and postoperative pain and reduce the use of opioid in abdominoplasty…
- Conditions
- Abdominal Obesity, Postoperative Pain, Postoperative Complications
- Trial name
- NCT06897345
- Testing
- transversus abdominis plane block, rectus sheat block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Obesity
Effect of Non-invasive Vagal Nerve Stimulation on Selected Outcomes in Central Obesity
Trans Cutanous Electric Nerve Stimulation of Auricular Vagus Nerve
- Trial name
- NVN-CO (NCT07341971)
- Testing
- Transcutanous Auricular vagus nerve stimulation
- Volunteers
- 60 people
- Sponsor
- Cairo University
Overweight and Obesity, Metabolic Syndrome
Testing the Adipose Expandability Hypothesis In Vivo During Overfeeding
Adipose, or fat, tissue is a plastic organ that retains the ability to expand and store excess calories during positive energy balance in humans.
- Trial name
- EAT 2 (NCT04583514)
- Testing
- Control, Overfeeding
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Abdominal, Diabetes
Exploratory Evaluation of the Effect of Cholestyramine on Serum Levels of POPs in Obese Female Patients
Environmental endocrine disruptors (EDCs) represent a major problem for human health.Some PEEs can accumulate in the fatty tissue of the human body thanks to their lipophilic nature, and are known as persistent organic pollutants…
- Conditions
- Obesity, Abdominal, Diabetes, Bariatric Surgery Candidate
- Trial name
- OBESE (NCT05966727)
- Testing
- Cholestyramine Powder
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Visceral Obesity, Metabolic Syndrome
Polygonatum Sibiricum Reduces Visceral Fat in Obese Adults
This study is being done to find out if a traditional Chinese herb called Polygonatum sibiricum (Huangjing) can help reduce belly fat and improve metabolic health in adults with visceral obesity.
- Trial name
- NCT07759323
- Testing
- Polygonatum sibiricum, Lifestyle Intervention
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Central Obesity
Effect of Ultrasound Cavitation on Insulin Resistance in Patients with Central Obesity in Female
The purpose of this study was to investigate the effect of ultrasound cavitation on insulin resistance, HbA1c and skin fold in patients with abdominal central obesity.
- Trial name
- NCT06729203
- Testing
- Ultrasound cavitation, Exercise
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Fitness Trackers, Cardio Vascular Disease
Effects of Wearable Device Functions and Health Coaching on Device-measured Movement Behaviours and Cardiometabolic Risk Factors in Adults With Central Obesity
This study is a randomized controlled trial. The objective of this study is to investigate: 1. the effects of 1-year evidence-based interventions incorporating wearable device functions alone on device-measured movement…
- Conditions
- Fitness Trackers, Cardio Vascular Disease, Physical Activities, Exercise
- Trial name
- NCT07379970
- Testing
- Fitbit Wearable Device, Lifestyle Coaching Program
- Where
- Hong Kong
- Volunteers
- 133 people
- Sponsor
- The University of Hong Kong
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Diet, Healthy, Obesity, Visceral
NUTritional Impact of a Hypocaloric Hyperprotein Diet Before Obesity Surgery
Obesity is a major public health problem and is constantly on the rise. Therapeutic approaches based on dietary advice, physical activity and the management of psychological difficulties are not always sufficient to achieve a…
- Conditions
- Diet, Healthy, Obesity, Visceral, Bariatric Surgery Candidate
- Trial name
- NUTRACOB (NCT04942093)
- Testing
- With low-calorie, high-protein diet, Without low-calorie, high-protein diet
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Obesity, Abdominal, Adiposity
Transcriptional Changes in Isolated Human Adipocytes During Obesity
Adipocytes play an important role in our body through their function as metabolic energy stores in the form of fat deposits, which are stored when metabolic energy is in excess and released when energy levels are low.
- Trial name
- NCT06907212
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
PostoperativePulmonaryComplications
A Multicenter Randomized Controlled Clinical Trial of the Impact of Minimally Invasive Abdominal Surgery Esophageal Pressure Monitoring Guided Individualized PEEP on Postoperative Pulmonary Complications in Obese Patients
The aim of this study is to compare the effect of individualized PEEP based on transmural lung pressure and fixed PEEP on postoperative pulmonary complications during laparoscopic or robotic abdominal surgery in obese patients.
- Trial name
- NCT06996288
- Testing
- Transpulmonary pressure-guided individualized PEEP
- Volunteers
- 180 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Obesity, Abdominal, Anesthesia Morbidity
CPAP in Patients With Severe Obesity After Anesthesia
The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1.
- Conditions
- Obesity, Abdominal, Anesthesia Morbidity, Apnea, Obstructive Sleep, Atelectases, Postoperative Pulmonary
- Trial name
- NCT06287632
- Testing
- Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Non-Alcoholic Fatty Liver Disease, Obesity, Morbid
Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
The study is aimed To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Morbid, Brown Fat, Metabolic Disease
- Trial name
- NCT03875625
- Testing
- Bariatric surgery, Dietitian led life style modification intervention, Conventional care (control)
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Abdominal Obesity
INNUPREC (Nutrigenetic Intervention for the Prevention of Cardiovascular Disease)
Background: Abdominal obesity (AO) is a multifactorial disease that affects 81.6% of the Mexican population; it is characterized by the excessive accumulation of adipose tissue in abdominal region.
- Trial name
- INNUPREC (NCT06847243)
- Testing
- Nutrigenetic diet according the genetic test, Control intervention group
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Steato-Hepatitis (NASH)
How Abnormal Function of Fat Tissue in Type 1 Diabetes Contributes to Fat in the Liver
Steatotic liver disease associated with metabolic dysfunction (MASLD) is a disease caused by excess fat storage in the liver. Excessive fat delivery to the liver and MASLD typically occurs in people with abdominal obesity and…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Steato-Hepatitis (NASH), Type 1 Diabetes Mellitus
- Trial name
- AGL14 (NCT07133854)
- Testing
- Imaging PET/MRI, Stable isotope infusions, meal test
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Obesity, Abdominal
Nicotinamide Adenine Dinucleotide (NAD+) Metabolism in Human Brown Adipose Tissue
A fully functional brown fat helps maintain a healthy weight and decreases the risk of metabolic diseases such as type II diabetes (T2DM).
- Trial name
- BATNAD (NCT06627868)
- Testing
- NAD+ precursor
- Where
- Finland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Turku
Central Obesity, Time Restricted Eating
Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physically Inactive Adults With Central Obesity
Time-restricted eating (TRE) has gained attention as a promising dietary strategy for enhancing body composition and metabolic health.
- Trial name
- NCT07062315
- Testing
- Chronotype-matched time-restricted eating, Chronotype-unmatched time-restricted eating
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Dynapenia, Abdominal Obesity
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life.
- Trial name
- NCT07180485
- Testing
- whole body vibration training, control group
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital