Clinical trials: Obesity, Morbid
Obesity, Morbid
Clinical Efficacy of a Virtual Reality Tool for the Treatment of Obesity
The objective of the study, which is framed within European Union's H2020 project titled SOCRATES, is to assess the clinical efficacy of a Virtual Reality (VR) embodiment tool for treating obesity and to compare it to usual care…
- Trial name
- SOCRATES (NCT05094557)
- Testing
- Experimental Group 1: Body swapping VR intervention + psychoeducational video + Treatment As usual, Experimental Group 2: VR intervention without body swapping + psychoeducational video + Treatment As usual, Control Group: Psychoeducational video + Treatment As usual
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Morbid Obesity, Metabolic Syndrome
The S.L.I.M.M.S. Procedure for Severe Clinical Obesity
Assessment of Gastric Bypass combined with Vertical Sleeve Gastrectomy as primary treatment for patients with severe clinical obesity.
- Conditions
- Morbid Obesity, Metabolic Syndrome, Type2 Diabetes, Insulin Resistance
- Trial name
- SLIMMS (NCT04592601)
- Testing
- S.L.I.M.M.S. Procedure
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- The N.E.W. Program
Cesarean Section
Transverse Supraumbilical Versus Pfannenstiel Incision for Cesarean Section in Morbidly Obese Women
This study aims to evaluate the efficacy and safety of transverse supraumbilical incision over Pfannenstiel incision in performing cesarean section for morbid obese pregnant women.
- Trial name
- NCT02692729
- Testing
- transverse supraumbilical, pfannenstiel incision
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Bariatric Surgery Candidate, Severe Obesity
Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision
The goal of this study is two part: 1) to add to the literature which is still somewhat sparse with numbers of patients undergoing the Single Anastomosis Duodenal Ileal Bypass (SADI) as a revision for laparoscopic sleeve…
- Trial name
- SADI (NCT04165694)
- Testing
- Single Anastomosis Duodenal Ileal Bypass (SADI)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Morbid Obesity
Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy
The sleeve gastrectomy that has been utilized as a first-stage bariatric procedure to reduce surgical risk in high-risk patients by induction of weight loss is now gaining popularity as a standalone procedure for the treatment of…
- Trial name
- NCT00667706
- Testing
- laparoscopic operation Sleeve Gastrectomy, laparoscopic operation Roux-en-Y Gastric bypass
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Severe Obesity, Bariatric Surgery
Study on Impact of Lifestyle Change and Weight Loss Before Bariatric Surgery
The purpose of the trial is to determine whether a preoperative lifestyle intervention (targeting diet, exercise, and preparation for surgery) will favorably impact obesity-related parameters prior to bariatric surgery and…
- Trial name
- PREP (NCT00623792)
- Testing
- Preoperative lifestyle Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duquesne University
Obesity, Morbid
Pre- and Postoperative Cognitive Behavior Therapy for Patients Accepted for Bariatric Surgery
The purpose of this study is to investigate the relationship between the potential predictive psychological variables and success after bariatric surgery.
- Trial name
- NCT00635011
- Testing
- psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Helse Fonna
Obstructive Sleep Apnea, Obesity
Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity
The purpose of this study is to develop a data driven system for persons with severe obesity sleep apnea that utilizes remote monitoring with health coaching to create behavior changes aimed at improving health and quality of…
- Trial name
- NCT05343000
- Testing
- Home-based pulmonary rehabilitation (PR) system
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Morbid Obesity, Bariatric Surgery
LAGB Versus VBG: 7-Year Results
The study aims to investigate the long term results of a randomized clinical single-centre trial comparing two standard operative techniques in bariatric surgery; laparoscopic adjustable gastric banding and vertical banded…
- Conditions
- Morbid Obesity, Bariatric Surgery, Vertical Banded Gastroplasty, Laparoscopic Adjustable Gastric Banding
- Trial name
- NCT00840736
- Testing
- Laparoscopic adjustable gastric banding, vertical banded gastroplasty
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University Medical Center
Obesity, Weight Loss
Self-compassion and Nutrition (SCAN) Study
The purpose of this study is to examine the feasibility of two approaches for improving long-term weight loss success among individuals with severe obesity.
- Trial name
- NCT04289636
- Testing
- Behavioral weight loss program, Self-compassion, Nutrition and cooking education
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Overweight and Obesity, Overweight or Obesity
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obesity
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding obesity.
- Conditions
- Overweight and Obesity, Overweight or Obesity, Obesity, Obesity, Morbid
- Trial name
- NCT04100616
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
The Prevalence of Surgery for Small Bowel Obstruction After LGBP Procedure.
Internal Hernia After Laparoscopic Gastric Bypass
To see if closing the mesenteric defects created at a Laparoscopic Gastric Bypass is better than leaving them open.
- Trial name
- NCT01137201
- Testing
- Suturing of mesenteric defects
- Where
- Sweden
- Volunteers
- 2,507 people
- Sponsor
- Region Örebro County
Obesity, Morbid, Ventilator-Induced Lung Injury
Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon
This is a research study to determine if identifying an optimal level of positive end-expiratory pressure (PEEP) targeted specifically to individualized patient characteristics will shorten the time on the ventilator.
- Conditions
- Obesity, Morbid, Ventilator-Induced Lung Injury, Respiratory Failure
- Trial name
- PROP OPEN (NCT03951064)
- Testing
- Esophageal balloon, Intervention Spontaneous Breathing Trial (SBT) and Extubation, Control Spontaneous Breathing Trial and Extubation
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of North Carolina, Chapel Hill
Leptin Deficiency, Obesity
Clinical Evaluation of Polyherbal Coded Formulation Obesecure for Leptin Regulation and Obesity Management
The study was designed to explore an alternative approach to reduce weight in human beings using a polyherbal formulation. A polyherbal formulation named as Obesecure was developed after screening of local medicinal flora.
- Trial name
- CEOLO (NCT04443790)
- Testing
- Leptin Human
- Where
- Pakistan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hafiz Muhammad Asif
Morbid Obesity
Laparoscopic Adjustable Gastric Banding in Adolescents
This study is to determine if the Lap-band system is safe and effective for use in morbidly obese adolescents.
- Trial name
- NCT01619488
- Testing
- Adjustable Gastric Band
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Kirk Reichard
Severe Obesity, GERD
Comparison of the Sleeve Gastrectomy Technique With a Nissen Fundoplication Added to the Conventional Sleeve Gastrectomy Technique in Morbidly Obese Patients
The purpose of this study is to evaluate the impact of the procedure (sleeve gastrectomy technique with a Nissen fundoplication (N-Sleeve) vs conventional sleeve gastrectomy technique
- Conditions
- Severe Obesity, GERD, Bariatric Surgery Candidate, Morbid Obesity
- Trial name
- N'SLEEVE (NCT04626232)
- Testing
- N-SLEEVE technique, SLEEVE
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Montpellier
Obesity
Aspiration Therapy in Asian Patients
This research project will provide insight into the efficacy and safety of aspiration therapy in the management of obesity and its comorbidities in the Asian population, and will determine if there is a role for this novel…
- Trial name
- NCT02881684
- Testing
- Aspiration Therapy (AspireAssist®), Lifestyle Therapy
- Where
- Hong Kong
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obesity, Obesity, Morbid
Deep Brain Stimulation for Morbid Obesity
This is an open-label, phase I pilot trial designed to evaluate the safety and feasibility of deep brain stimulation (DBS) for the treatment of refractory morbid obesity.
- Trial name
- NCT03650309
- Testing
- Deep Brain Stimulation
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Morbid Obesity
Liposomal Amphotericin B (AmBisome) Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ASPEN)
Dosing guidelines for liposomal amphotericin B (AmBisome) in (morbidly) obese patients are not available. Subsequently, the pharmacokinetic profile of AmBisome in this specific patient population is still largely unknown.
- Trial name
- NCT02320604
- Testing
- Administration of study drug
- Where
- 2 sites in Netherlands
- Volunteers
- 16 people
- Sponsor
- Radboud University Medical Center
Obesity, Pediatric, Obesity, Childhood
Efficacy of Vitamin D Supplementation in Obese Children
Vitamin D deficiency is common in the general population in the United States, but is more common in overweight and obese children.
- Conditions
- Obesity, Pediatric, Obesity, Childhood, Obesity, Morbid, Vitamin D Deficiency
- Trial name
- NCT02956408
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Columbia University