Clinical trials: Obesity, Overweight
Obesity
Effect of Different Intensities of Exercise on Daily Energy Expenditure With Physical Activity in Overweight Boys
The main purpose of this study is evaluate the effect of different intensities of exercise (moderate vs. intense) on the daily energy expenditure in overweight adolescents.
- Trial name
- PAPPAS2 (NCT02272088)
- Testing
- physical activity-moderate, Intense physical activity
- Volunteers
- 24 people
- Sponsor
- Rio de Janeiro State University
Obesity in Adolescents
Impact of a Targeted Nutritional Intervention on Glycaemic Variability and Correlation Between Glycaemic Parameters and Satiety.
Obesity affects 18% of French adults and increasingly impacts adolescents. Dietary management is challenging, particularly with eating disorders like hyperphagia.
- Trial name
- APETIT (NCT07771842)
- Testing
- The primary intervention in this study is dietary counseling and education on adopting a low glycaemic index diet with sample menus provided, continuous glucose monitoring (CGM) sensors
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Obesity
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
In this study we will be looking into how CagriSema influences metabolism (the process by which food is used to supply energy for the body) compared to a diet. CagriSema is a new investigational medicine.
- Trial name
- NCT07184086
- Testing
- CagriSema (Cagrilintide B + semaglutide I), Low Energy Diet
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Novo Nordisk A/S
Obesity
Telemedicine Follow-up for Bariatric Surgery Patients: What Do Patients Prefer
This is a randomized clinical trial that will randomize bariatric patients undergoing laparoscopic sleeve gastrectomy or laparoscopic Roux-en-Y gastric bypass to receive either in-person or telemedicine post-operative follow-up…
- Trial name
- NCT04784286
- Testing
- Telemedicine 30-day post-op visit, In-Person 30-day post-op visit
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Asthma
Anti-Inflammatory Lipid Mediators in Asthma
The purpose of this study is to demonstrate the efficacy and safety of 10-nitro-9(E)-octadec-9-enoic acid (CXA-10) in obese adult asthmatics.
- Trial name
- ALMA (NCT03680976)
- Testing
- CXA-10
- Where
- United States
- Sponsor
- Sally E. Wenzel MD
Obesity
A Study That Will Evaluate Ketogenesis and Glucose-Dependent Insulin Secretion Methodologies in Healthy Male Subjects (MK-0000-159)(COMPLETED)
This study will test the hypotheses that a single dose of oxyntomodulin (OXM) will be neutral or better than placebo in lowering ambient glucose levels during a graded glucose infusion (GGI) and that a single dose of OXM will…
- Trial name
- NCT01055340
- Testing
- Oxyntomodulin (OXM), Comparator: Oxyntomodulin (OXM)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes Mellitus, Overweight and Obesity
Safety and Efficacy of Human Microbiota Transplantation for Overweight and Obese Type 2 Diabetes Mellitus
The main purpose is to evaluate whether the percentage of body weight change from baseline to week 12 is higher than that in the placebo group.
- Trial name
- SETOM (NCT05253768)
- Testing
- Fecal microbiota transplant (FMT), normal saline and glycerin/food coloring
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Zhujiang Hospital
Obesity, Lifestyle, Healthy
Twelve-year Follow-up on the Treatment of Obese Pregnant Women (TOP) Study
The participant (both mother and child) in the initial TOP study will be invited to a follow-up study to evaluate the effect of life style intervention during pregnancy on both mother and their offspring 12 years after the…
- Conditions
- Obesity, Lifestyle, Healthy, Diet, Healthy, Follow-up
- Trial name
- TOP12 (NCT05446220)
- Testing
- Lifestyle intervention
- Where
- Denmark
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Type 2 Diabetes Mellitus, Overweight and Obesity
Type 2 Diabetes Treatment and Remission With a Very Low-Calorie Ketogenic Diet (VLCKD) and Lifestyle Changes
There is a strong correlation between being overweight, specifically with abdominal fat, and type 2 diabetes mellitus (T2DM). Recent scientific literature has highlighted the connection between significant weight loss…
- Trial name
- NCT05984459
- Testing
- VLCKD
- Where
- Switzerland
- Volunteers
- 39 people
- Sponsor
- Cabinet Medical
Bariatric Surgery, Obesity
Acute Effect of EPAP and Noninvasive Ventilation on Pulmonary Function and Lung Regional Ventilation on Bariatric Surgery
Obesity is a non-communicable chronic disease of multifactorial, involving biological, historical, ecological, economic, social, cultural and political.
- Conditions
- Bariatric Surgery, Obesity, Physical Therapy Modalities
- Trial name
- NCT02577744
- Testing
- Noninvasive Ventilation, Expiratory Positive Air Pressure
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness
THE EFFECT OF MOTİVATİONAL INTERVİEWİNG-BASED MİNDFULNESS INTERVENTION ON WEİGHT MANAGEMENT AFTER WEİGT LOSS,7SLİMMİNG SURGERY: A RANDOMİZED CONTROLLED TRIAL.
Obesity is one of the most critical health problems in developed and developing countries, recognized as a chronic disease that adversely affects both individual and societal health.
- Conditions
- Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness, Not Having Previously Received Cognitive Awareness Training, Not Having Undergone Revision Surgery
- Trial name
- NCT07351214
- Testing
- A MİNDFULNESS İNİTİATİVE BASED ON MOTİVATİONAL İNTERVİEWİNG
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duygu Ateş
Diabetes, Morbid Obesity
Closed Incision Negative Pressure Wound Therapy vs. Foam as Post Operative Dressing
The primary objective is to assess the frequency of a wound healing complication, in a closed incisional wound in a "high risk" surgical incision when treated with Negative Pressure Wound Therapy versus a highly absorbent…
- Conditions
- Diabetes, Morbid Obesity, Lymphedema, Orthopedic Disorder
- Trial name
- NCT05427916
- Testing
- Avance Solo, Optifoam
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Over Weight
Medico-economic Evaluation of Obesity
The investigators developed the Aviitam® online platform. The purpose of the project is to test the medico-economic impact related to the utilization of the Aviitam online platform in primary care.
- Trial name
- NCT02761538
- Testing
- AVIITAM
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Obesity
Effectiveness of an Eight Week Online Mediterranean Based Diet
This research is examining whether an 8-week online nutritional programming based on a Mediterranean diet can achieve meaningful increase intake of a Mediterranean based diet and improvements in measures of body weight and…
- Trial name
- NCT01532258
- Testing
- Go! Foods for You without Weekly MA Support., Go! Foods for You with Weekly MA Support.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Childhood Obesity
Alberta Project Promoting Active Living and Healthy Eating in Schools
The objectives were to 1) make students eat healthier and be more active; and 2) prevent overweight and obesity. Children will therefore be less likely overweight or obese.
- Trial name
- APPLE Schools (NCT01914185)
- Testing
- Comprehensive School Health (CSH)
- Where
- Canada
- Volunteers
- 8,663 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obesity, Overweight
A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body Weight
The purpose of the study is to determine the effect of semaglutide on gastric emptying in people with obesity. Participants will receive either semaglutide or placebo, and the treatment assigned will be decided by chance.
- Trial name
- NCT07845578
- Testing
- Semaglutide, Paracetamol
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Novo Nordisk A/S
Obesity
A Comparative Study of KES524 in Patients With Obesity Disease
To investigate the efficacy and safety of KES524 in patients with obesity (visceral fat obesity with type 2 diabetes and dyslipidemia), a 52-week, double-blind, placebo-controlled comparative study is conducted.
- Trial name
- NCT00165685
- Testing
- Sibutramine Hydrochloride Monohydrate
- Where
- 20 sites in Japan
- Sponsor
- Eisai Limited
Opioid Use, Unspecified, Bariatric Surgery Candidate
Evaluation of the Stress Response in Bariatric Surgery With and Without the Use of Opioids
The goal of this clinical trial is to compare Opioid Free and Opioid Based Anaesthesia in patients undergoing sleeve gastrectomy.
- Trial name
- NCT05752799
- Testing
- Opioid Free Anaesthesia, Opioid based anesthesia
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Obesity, Childhood
Development of an Eating Behavior Risk Score
This study will explore how children's eating behaviors are connected to brain activity and body fat levels. Researchers are especially interested in a behavior pattern called the PACE phenotype, which includes how much children…
- Trial name
- PACE (NCT07266506)
- Testing
- Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity, Childhood
Lactoferrin Versus Iron Supplement in Irondeficiency Anemia and Weight Loss in Obese Children
The effect of lactoferrin versus iron supplement in treating iron deficiency anemia and helping weight loss in obese school age children
- Trial name
- NCT04014855
- Testing
- Iron Supplement
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
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