Clinical trials: Obesity, Overweight
Weight Loss, Obesity
Optimizing Weight Loss. Can Continuous Glucose Monitoring Play a Role
The goal of this clinical trial is to determine the potential effectiveness of adding Continuous Glucose Monitoring to a personalized weight loss maintenance program in improving weight loss maintenance.
- Trial name
- OWL-CGM (NCT05890209)
- Testing
- Continuous Glucose Monitoring device
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Binge Eating Disorder
Digital Mindfulness Meditation-enhanced Cognitive Behavioral Therapy (CBT-MM) for Binge Eating Disorder
The investigators will evaluate the acceptability and feasibility of a 18-week long digital mindfulness-based and cognitive behavioral therapy intervention for binge eating disorder.
- Trial name
- NCT06604299
- Testing
- Meditation-enhanced Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Yeshiva University
Weight Loss, Weight Change, Body
Study of an International Commercial Program on Weight Loss and Health Outcomes
This study is a randomized controlled trial (RCT) of the Weight Watchers (WW) Freestyle ® (Flex® in UK) weight loss program compared to a control group following a do-it-yourself (DIY) approach for 12 months.
- Conditions
- Weight Loss, Weight Change, Body, Obesity, Diet Modification
- Trial name
- NCT03571893
- Testing
- Weight Watchers Freestyle (Flex), DIY Personal Plan
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 373 people
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Abdominal
Waist Circumference in Cardiac Surgery
Metabolic syndrome including increased body mass index or waist circumference is known to be a risk factor of cardiovascular disease.
- Trial name
- NCT03605121
- Testing
- cardiac surgery
- Where
- South Korea
- Volunteers
- 5,000 people
- Sponsor
- Seoul National University Hospital
Hip Osteoarthritis
Obesity's Impact on the Effect of Hip Arthroplasty
The purpose of this study is to investigate whether there is a correlation between hip arthroplasty patients' preoperative weight and the patients quality of life and the clinical effect one year postoperatively.
- Trial name
- NCT01496716
- Testing
- Hip arthroplasty
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- University of Aarhus
Obesity, Outpatient Surgery
The Same-Day and One Day Gastric Bypass by Use the "FundoRing" Method (Same-Day_FundoRing Trial)
Outpatient surgery means that patient have surgery and often go home the same day. Safety and utilization outcomes were similar between outpatient and inpatient bariatric surgery, and outpatient was associated with shorter…
- Conditions
- Obesity, Outpatient Surgery, Same-Day Surgery
- Trial name
- NCT07189416
- Testing
- Laparoscopic One Anastomosis Gastric Bypass by Use the "FundoRing" method with Enhanced Recovery Protocol and Remote Monitoring in Ambulatory Surgery Center with Integrated Apartments
- Where
- Kazakhstan
- Volunteers
- 200 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Metoprolol
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03519906
- Testing
- Metoprolol
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Critical Illness
Levofloxacin Pharmacokinetics (PK) in the Severely Obese
Obesity is known to affect the concentrations of certain medications in the body. Levofloxacin is a commonly used antibiotic. Based on what the investigators know about levofloxacin and how it moves through the body, obesity may…
- Trial name
- NCT00176306
- Testing
- Levofloxacin 750 mg IV
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Joel Thompson, PhD
Overweight or Obesity and Elevated Liver Fat
A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight
The main objective of this trial will be to determine whether maridebart cafraglutide is superior to placebo on reduction in liver fat content and body weight in participants living with obesity or overweight and elevated liver…
- Trial name
- NCT07441252
- Testing
- Maridebart cafraglutide
- Where
- 23 sites in United States
- Volunteers
- 180 people
- Sponsor
- Amgen
Obesity, Weight Loss
Attitudes Toward Food During a Weight Loss Intervention
The purpose of this study is to evaluate whether the Noom Healthy Weight Program, a digital behavior change weight loss intervention, creates a positive relationship with food, compared to a waitlist control group.
- Conditions
- Obesity, Weight Loss, Overweight and Obesity, Overweight or Obesity
- Trial name
- NCT04586647
- Testing
- Noom Healthy Weight; mobile behavior change program for weight loss.
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Noom Inc.
Type 2 Diabetes Mellitus
A Clinical Trial to Study the Efficacy, Safety, Tolerability and Pharmacokinetics of P2202 in Patients of Type 2 Diabetes
It is a phase II, randomized, double-blind, placebo-controlled study of P2202 in patients of type 2 diabetes mellitus, inadequately controlled with a stable dose of metformin or sulfonylurea or both.
- Trial name
- NCT01674348
- Testing
- P2202
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Piramal Enterprises Limited
Cardiovascular Diseases, Heart Diseases
National Growth and Health Study (NGHS)
To determine if the Black-white differences in the development of obesity in pubescent females were due to differences in psychosocial, socioeconomic and other environmental factors.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Coronary Disease
- Trial name
- NCT00005132
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
COVID-19, Chronic Heart Failure
Analysis of Health Status of Сomorbid Adult Patients With COVID-19 Hospitalised in Fourth Wave of SARS-CoV-2 Infection
Depersonalized multi-centered registry initiated to analyze dynamics of non-infectious diseases after SARS-CoV-2 infection in population of Eurasian adult patients.
- Conditions
- COVID-19, Chronic Heart Failure, Diabetes Mellitus, Chronic Kidney Diseases
- Trial name
- ACTIV4 (NCT05226416)
- Where
- Russia
- Volunteers
- 3,554 people
- Sponsor
- Eurasian Association of Therapists
Cardiovascular Diseases, Hypertension
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
The CONNECT: "Developing a learning COmmunity to increase eNgagemeNt and Enrollment in cardiovascular Clinical Trials" is comprehensive, participant-centered learning platform designed to increase diversity in cardiovascular…
- Conditions
- Cardiovascular Diseases, Hypertension, Diabetes Type 2, Stroke
- Trial name
- CONNECT (NCT06347484)
- Testing
- EHR-informed Recruitment Method of Contact, Educational Text-Messages and Connection to Cardiovascular Research Opportunities
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stroke, Obesity
Secondary Prevention of Stroke Through Non-drug Therapeutic Weight Reduction
SCENARIO is a trial to investigate the role of non-drug weight reduction in secondary prevention of stroke. It is a single-blinded, randomized, controlled multicentre trial with two arms.
- Trial name
- SCENARIO (NCT01721538)
- Testing
- Weight reduction program, Lecture on healthy nutrition
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Philipps University Marburg
Obesity, Cardiovascular Diseases
A Clinical Trial Of Two Educational Strategies In Cardiovascular Health In Child Population
AIM: To evaluate the effectiveness of two strategies in cardiovascular risk in children 2º grade in the community of Madrid. DESIGN: cluster-randomized trial with blinded evaluator SCOPE AND SUBJECTS OF STUDY: Children of both…
- Trial name
- SAVINHEARTS (NCT01418872)
- Testing
- Didactic Concerts
- Where
- Spain
- Volunteers
- 1,730 people, healthy volunteers welcome
- Sponsor
- Agencia Lain Entralgo
Obesity
Efficacy and Safety of Soybean Germ Extract on Decrease of Body Fat
This study was conducted to investigate the effects of daily supplementation of Soybean germ extract on decrease of body fat
- Trial name
- NCT03826212
- Testing
- Soybean Germ Extract
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Diabetes Mellitus, Diabetes Mellitus, Type 2
The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes
Glucagon-like peptide 1 (GLP-1) based therapies, such as exenatide, are already successfully employed in the treatment of Type 2 Diabetes (T2DM).
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, Obesity
- Trial name
- Braini-Ex (NCT01281228)
- Testing
- exenatide, exenatide + exendin (9-39)
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Obesity & Overweight, Gut -Microbiota
Effects of Monday-Thursday Sunnah Fasting on Short-Chain Fatty Acids, GLP-1, Satiety, and Nutritional Status in Obese Males
This quasi-experimental study investigated the effects of 8 weeks of Monday-Thursday Sunnah fasting on fecal short-chain fatty acids (SCFA), fasting total GLP-1, appetite regulation (hunger and satiety area under the curve)…
- Trial name
- NCT07703865
- Testing
- Monday-Thursday Sunnah Dry Fasting
- Where
- Indonesia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Muhammadiyah Jakarta
Morbid Obesity, Weight Reduction
Improving Patient Decisions About Bariatric Surgery
At least 15 million Americans are morbidly obese, or more than 100 pounds overweight. Medical treatments including drugs and behavior modification have proven ineffective in producing significant and lasting weight loss in this…
- Trial name
- PCORI (NCT02364128)
- Testing
- Decider Guider: Weight Loss
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Michigan
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