Clinical trials: Obesity, Overweight
Obesity, Anxiety
Clusters in Obesity: Intuitive Eating and Mental Health Key for Personalisation
Objective: To determine clusters among weight-loss-seeking individuals for personalised obesity management and find questionnaires to help identify those who could benefit from psychological support.
- Conditions
- Obesity, Anxiety, Stress
- Trial name
- NCT06125600
- Testing
- Clustering of people living with obesity using behavioural questionnaires
- Where
- France
- Volunteers
- 989 people
- Sponsor
- University Hospital, Montpellier
Obesity
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
Background Obesity and physical inactivity contribute substantially to cardiovascular disease risk, diabetes, hypertension, and dyslipidemia.
- Trial name
- NCT03288207
- Testing
- AMRA(r) Researcher Image reconstruction software, MRI: radiofrequency coils (Device Manufacturer: Siemens Medical Solutions USA, Inc.), MRI: Research pulse sequences (Device Manufacturer: NIH)
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Overweight and Obesity
Satiety Innovation- Study 793. University of Aberdeen
The proposed study will address the effect of developed novel food products through processing innovation on motivation to eat, biomarkers of satiety, nutrient bioavailability and gut health using in vivo studies and validating…
- Trial name
- SATIN (NCT01724411)
- Testing
- Resistant Starch type 3
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- P Burns
Type 2 Diabetes Mellitus, Binge-Eating Disorder
Preventing Type 2 Diabetes in Black Emergent Adult
Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults.
- Conditions
- Type 2 Diabetes Mellitus, Binge-Eating Disorder, Binge Eating, Obesity
- Trial name
- NCT06848244
- Testing
- Appetite Awareness Training (AAT), Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Drug Drug Interaction (DDI), Pharmacokinetics and Pharmacodynamics
Phase I Drug-Drug Interaction Study of UBT251 Injection in Participants With Overweight or Obesity
This is a Phase I, open-label, two-cohort study designed to evaluate the drug-drug interaction potential of multiple-dose UBT251 Injection in adult participants with overweight or obesity.
- Trial name
- NCT07785934
- Testing
- UBT251, Metformin hydrochloride, Warfarin Sodium
- Where
- China
- Volunteers
- 48 people
- Sponsor
- The United Bio-Technology (Hengqin) Co., Ltd.
Obesity
A Dissonance-Based Obesity Intervention
This project will examine the feasibility and acceptability of Enhanced Project Health, a dissonance-based obesity intervention, and whether this intervention results in significantly greater reductions in weight and improvements…
- Trial name
- NCT04068493
- Testing
- Enhanced Project Health
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Metabolic Syndrome
Effect of Gymnema Sylvestre on Metabolic Syndrome and Insulin
Gymnema sylvestre has demonstrated promising effects in the treatment of obesity, dyslipidemia, hypertension, insulin secretion, among others.
- Trial name
- NCT02370121
- Testing
- Gymnema Sylvestre
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Intestinal Barrier Function, Chronic Inflammation
Reduction of Obesity-Associated Intestinal Inflammation by Low-Fat Dairy Yogurt
The main objective of this work is to conduct a clinical trial in obese and non-obese individuals testing the ability of low-fat dairy yogurt to improve gastrointestinal health and reduce chronic inflammation.
- Trial name
- NCT01686204
- Testing
- Low fat dairy yogurt, Soy pudding
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Sexual Dysfunction, Endothelial Dysfunction
Effects of Diet-induced Weight Loss in Obese Men
This study aims to compare the efficacy of a partial meal replacement diet with a conventional diet, for inducing weight loss and improving metabolic and inflammatory profile, endothelial function, erectile function, sexual…
- Conditions
- Sexual Dysfunction, Endothelial Dysfunction, Quality of Life, Inflammation
- Trial name
- NCT01554865
- Testing
- Optifast, Conventional diet counseling
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Obesity, Bariatric Surgery
Obesity: Prospective Evaluation of Upper Airway Obstruction and Compliance in Obese Patients in Pre and Post Bariatric Surgery
This clinical trial is a monocentric, prospective, observational and controlled trial (historical cohort control group of healthy non-obese subjects who had Nasal functional exploration for Snoring) as part of current care.
- Trial name
- OBANEZ (NCT03360565)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Fungal Infection
Effect of Weight and/or Obesity on Caspofungin Drug Concentrations
This study will find how weight affects the dosing of a drug called caspofungin. Currently, the amount of caspofungin a patient receives is the same regardless of the patient's weight.
- Trial name
- NCT01062165
- Testing
- Caspofungin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Overweight and Obesity, Physical Activity
Understanding Mechanisms of Exercise Behavior Change
This research seeks to examine psychological factors that may impact relationship between incentives and health behavior engagement, specifically physical activity.
- Conditions
- Overweight and Obesity, Physical Activity, Incentives
- Trial name
- NCT03465800
- Testing
- self-monitoring, daily incentives, delayed lump sum incentives
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Diabesity
Establishment of Hong Kong Diabesity Register
All participants of the Diabesity Register will receive structured assessment by nurses guided by the JADE portal at baseline including eye, feet, blood and urine examination with evaluation of BMI, blood pressure, HbA1c, lipid…
- Trial name
- NCT07247409
- Testing
- No Intervention: Observational Cohort
- Where
- Hong Kong
- Volunteers
- 800 people
- Sponsor
- Chinese University of Hong Kong
Overweight and Obesity, Severe Obesity
Connect for Health Pediatric Weight Management Program
The overall aim of this study is to disseminate the evidence-based Connect for Health program, specifically targeting pediatric primary care practices that deliver care to low-income children in the US who have a…
- Trial name
- NCT04042493
- Testing
- Connect for Health
- Where
- 3 sites in United States
- Volunteers
- 19,304 people
- Sponsor
- Massachusetts General Hospital
Childhood Obesity
Predictors of Success in an Intervention Program for the Treatment of Childhood Obesity
The child health and sports center, at the Meir Medical Center, runs for over 10 years an intervention program to treat obese children. The program includes physical activity, nutritional intervention and behavioral treatment.
- Trial name
- NCT01578863
- Testing
- Intervention program for obese children
- Where
- Israel
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Obesity, Women
Lactobacillus Gasseri and Hormonal Regulation in Obese Women
To evaluate the regulatory effect of Lactobacillus gasseri LG08 formula on visceral fat metabolism and sex hormone balance in obese women.
- Trial name
- NCT07502404
- Testing
- Probiotic, Maltodextrin
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity, Osteoarthritis
Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial)
The purpose of the SWIFT Trial is to answer two research questions. 1. Does bariatric surgery before total knee arthroplasty (TKA) improve both perioperative and long-term outcomes of TKA in extreme obesity? 2.
- Trial name
- SWIFT (NCT02598531)
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Geisinger Clinic
Obesity, Healthy Diet
Pricing Interventions Based on Energy Content in Restaurants
The goal of this clinical trial is to examine the impact of price decreases based on energy content in a full-service restaurant on immediate dietary consumption (in terms of kilocalories (kcals), sugar, fat, and salt intake) and…
- Conditions
- Obesity, Healthy Diet, Eating Behavior
- Trial name
- NCT05818345
- Testing
- Pricing intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Obesity
Effect of LAPS-Exendin on Body Weight in Obese Population
The purpose of this study is to determine the optimal dose and regimen of HM11260C, in combination with a hypocaloric diet, to reduce weight in obese subjects who are otherwise considered in stable health.
- Trial name
- NCT02075281
- Testing
- HM11260C
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
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