Clinical trials: Obesity, Overweight
Obesity, Weight Loss
Flipped Classroom for Weight Management
This study is a 24-week, single-arm trial investigating the feasibility of a flipped classroom behavioral intervention for weight management.
- Trial name
- NCT06622278
- Testing
- Flipped Classroom
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Kansas Medical Center
Metabolism and Nutrition Disorder, Obesity
Investigation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Dosing of NNC0174-0833 in Subjects With Obesity or Overweight
This trial is conducted in The United States of America. The aim of this trial is to investigate Safety, Tolerability, Pharmacokinetics (the exposure of the trial drug in the body) and Pharmacodynamics (the effect of the…
- Trial name
- NCT02958085
- Testing
- NNC0174-0833
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Novo Nordisk A/S
Obesity
The Effect of Traxi Panniculus Retractor on Surgical Time at Non-emergent Cesarean Delivery in Obese Women
This is an unblinded, randomized control trial of obese women to evaluate the impact of the Traxi Panniculus Retractor (TPR) on the cesarean operative time and surgical blood loss when compared to silk tape.
- Trial name
- NCT04458415
- Testing
- Traxi Panniculus Retractor (TPR), Silk Tape
- Where
- United States
- Sponsor
- Geisinger Clinic
Lung Diseases, Sleep Apnea Syndromes
Sleep Apnea in Elderly Male Twins
To conduct a genetic analysis of anatomic risk factors for sleep apnea in a well-characterized United States population-based registry of elderly male twins who have been successfully followed for the past 30 years.
- Conditions
- Lung Diseases, Sleep Apnea Syndromes, Obesity
- Trial name
- NCT00005525
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sleep Apnea, Obstructive, Hypertension
Epidemiology and Intervention of Obstructive Sleep Apnea Based on Community
This observational study in a real-world community was designed to perform epidemiological investigation and assess effect of CPAP intervention of obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive, Hypertension, Obesity, Diabetes
- Trial name
- NCT03280914
- Testing
- Auto-CPAP
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Guangdong Provincial People's Hospital
Polycystic Ovary Syndrome
Auricular Acupressure (AA) For Overweight/Obese Adolescent and Young Polycystic Ovary Syndrome ( PCOS)
The purpose of this trial is to investigate the effect and safety of auricular acupressure on adolescent and young women with PCOS.
- Trial name
- NCT02326714
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Obesity Hypoventilation Syndrome
A Trial of Rehabilitation in Obesity Hypoventilation Syndrome (OHS)
Obesity is an escalating problem in the UK and a proportion of these patients have a condition known as Obesity Hypoventilation Syndrome (OHS).
- Trial name
- NCT01483716
- Testing
- Rehabilitation
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Obesity
KEtogenic Diet and Its Multiple EffectS on Obesity
The prevalence of obesity and metabolic disturbances is worryingly increasing worldwide, therefore the study of their pathophysiology is extremely important to find new strategies for their treatment.
- Trial name
- KEMESO (NCT05898204)
- Testing
- Ketogenic diet, Balanced diet
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- University of Roma La Sapienza
Obesity, Childhood, Insulin Resistance
Studying the Effect of Mediterranean Diet on Insulin Resistance Among Obese Children and Adolescents
Insulin resistance is a common complication of childhood obesity. It is considered to be an important link between adiposity and the risk factor of type 2 diabetes in children.
- Trial name
- NCT04313452
- Testing
- the effect of Mediterranean diet on insulin sensitivity among obese children and adolescents aged
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Obesity, Adolescent, Lifestyle, Healthy
Mediterranean Enriched Diet for Tackling Youth Obesity
The prevalence of obesity is one of the main public health problems worldwide, reaching 18% among young people between 5 and 19 years of age in 2016. One possibility of effective treatment can be the Mediterranean diet (MD).
- Conditions
- Obesity, Adolescent, Lifestyle, Healthy, Diet, Healthy, Cardiovascular Risk Factor
- Trial name
- MED4Youth (NCT04719052)
- Testing
- Diet and behavioural intervention
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
PreDiabetes, Obesity
Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents
The study aims to investigate possible effects of per os Crocus Kozanis administration in children and adolescents with obesity
- Conditions
- PreDiabetes, Obesity, Dyslipidemias
- Trial name
- NCT05572749
- Testing
- Crocus Kozanis, Metformin
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- Aristotle University Of Thessaloniki
Urinary Incontinence, Obesity
BUDI (Bariatric UroDynamic Improvement)
In the population of obese women, the prevalence of urinary incontinence (UI) is around 70%. It was shown in the literature that weight loss by bariatric surgery allowed a significant improvement in the symptoms and impact on the…
- Conditions
- Urinary Incontinence, Obesity, Urodynamics, Quality of Life
- Trial name
- BUDI (NCT03509038)
- Testing
- Exploratory pathophysiology Study
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Caen
Obesity
Open-Label Extension (OLE) Study for Safety and Efficacy of Velneperit (S-2367) in Obese Subjects
The purpose of this open-label extension study is to evaluate the safety and efficacy of velneperit (S-2367) in obese subjects.
- Trial name
- OLE (NCT00788528)
- Testing
- S-2367 (velneperit)
- Where
- 73 sites in United States
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Shionogi
Obstructive Sleep Apnea
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy
This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are not on PAP therapy and are…
- Trial name
- MARITIME-OSA-2 (NCT07226765)
- Testing
- Maridebart cafraglutide
- Where
- 57 sites in United States, Australia and 9 more
- Volunteers
- 250 people
- Sponsor
- Amgen
Obesity, Obstructive Sleep Apnea Syndrome
Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents
Obesity has reached epidemic proportions in the United States with roughly 20% of American children being overweight and has serious consequences such as sleep apnea.Additionally, obesity is known to result in the earlier onset…
- Trial name
- NCT00222963
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Metabolic Syndrome, Obesity
New Biomarkers for Predicting Systemic Complications in Obesity
This observational cross-sectional study classified participants into obesity classes (Class I: BMI 30.0-34.9, Class II: 35.0-39.9, Class III: ≥40.0 kg/m²) based on WHO criteria.
- Trial name
- NCT07260487
- Where
- Turkey (Türkiye)
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Obesity, Hepatic Insufficiency
Study Examining The Effect Of Hepatic Impairment On Safety, Toleration And How The Body Processes An Experimental Drug
CP-945,598 is eliminated following extensive metabolism. Decrease hepatic function can affect its elimination from the body via metabolism.
- Trial name
- NCT00645021
- Testing
- CP-945,598
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Overweight, Obesity
A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide
The purpose of this study is to learn more about how tirzepatide affects stomach emptying in overweight/very overweight participants. Participants include those without diabetes and those with type 2 diabetes.
- Conditions
- Overweight, Obesity, Diabetes Mellitus, Type 2
- Trial name
- NCT04407234
- Testing
- Tirzepatide, Acetaminophen
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Eli Lilly and Company
Psychotic Disorders
Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics
This study will test the effectiveness of two different treatments for children and adolescents who have gained weight on their antipsychotic medications.
- Trial name
- IMPACT (NCT00806234)
- Testing
- Aripiprazole or Perphenazine, Metformin, Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone, paliperidone, or olanzapine/fluoxetine
- Where
- 4 sites in United States
- Volunteers
- 127 people
- Sponsor
- Johns Hopkins University
Obesity (Disorder)
Characterisation of MNEsic Involvement in Patients With Obesity.
The aim of the study is therefore to characterise memory impairment in a middle-aged population with obesity and to clarify the role of inflammation in obesity-related memory impairment.
- Trial name
- MNEMOB (NCT07796932)
- Testing
- RMI and Questionnaires
- Volunteers
- 150 people
- Sponsor
- University Hospital, Bordeaux
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