Clinical trials: Obesity, Overweight
Prader-Willi Syndrome
Characterization of Serum Proteome in Subjects With Prader Willi Syndrome (PROTEOMARKER)
The lack of serum markers that can be used to identify the levels of steatosis in obese subjects, or that can indicate a rapid progression of the metabolic disease, in which it is very often difficult to perform analyzes with…
- Trial name
- PROTEOMARKER (NCT05761184)
- Testing
- Serum collection for proteomic analysis
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Istituto Auxologico Italiano
Obesity, Childhood
Expanding Health System Intervention Through The Women, Infants and Children (WIC) Program Partnership
Pilot test the health system-based intervention to improve family beverage choices and promote water consumption, engaging WIC nutritionists to augment the intervention with follow-up and counseling of families at…
- Trial name
- WHISPER (NCT05356338)
- Testing
- Pilot Intervention to reduce SSB consumption in children and families enrolled in WIC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Morbid, Bariatric Surgery Candidate
Adipose Tissue Inflammation in Individuals Undergoing Bariatric Surgery
A growing body of work done over the past few decades has established that adipose tissue as an active endocrine organ which secretes a wide range of metabolic and immunological factors collectively called "adipokines (1)."…
- Trial name
- NCT03419273
- Testing
- bariatric surgery
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity
Nutritious Eating With Soul at Rare Variety Cafe
To date, few dissemination and implementation (D\&I) studies exist of successful healthy eating interventions delivered through restaurant settings.
- Trial name
- NEWSoul@RV (NCT04513769)
- Testing
- Vegan diet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Obesity / Overweight, Obesity (BMI Equal to or >30)
A PHASE 2A, EXPLORATORY, RANDOMIZED, SINGLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY OF WEIGHT LOSS INDUCED BY NKS-3 IN OBESE ADULTS.
This study is designed as a single-blind, placebo-controlled, randomized, parallel-group trial. Subjects will be randomized in a 2:1 ratio to receive either NKS-3 or matching placebo, with a total planned enrollment of 31…
- Trial name
- SERENITY-1 (NCT07882654)
- Testing
- Investigational product is a modified linoleic acid, named NKS-3. This non-caloric agent, synthetized from linoleic acid, is a fat taste receptors agonist, targeting CD36 with also an impact on GPR120
- Where
- Tunisia
- Volunteers
- 31 people
- Sponsor
- EktaH
Pediatric Obesity
Fuel for Fun: Cooking With Kids Plus Parents and Play
Fuel for Fun: Cooking with Kids Plus Parents and Play (FFF), is an integrated research, extension, and education project targeting 4th grade students.
- Trial name
- FFF (NCT02491294)
- Testing
- School, Family, About Eating
- Where
- United States
- Volunteers
- 2,640 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Morbid Obesity
Outcomes of Sleeve Gastrectomy in Obese Patients, Retrospective Study.
This study will be a retrospective study in which we will review patients who underwent laparoscopic sleeve gastrectomy at Sohag University Hospital in the period from january 2017 to May 2018.Assessment of outcomes as Effects on…
- Trial name
- NCT04967053
- Testing
- sleeve gastrectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Obesity
Indole-3-Carbinol Effects on Estrogen Metabolism
This study will test a dietary supplement, indole-3-carbinol, for improving the estrogen profile in women across a range of body mass index.
- Trial name
- NCT00988845
- Testing
- Indole-3-carbinol
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Incomplete Reversal of Neuromuscular Block
Sugammadex ED90 Dose in the Obese Patients
The purpose of this study is to determine the minimum effective dose of sugammadex, an antagonist of neuromuscular blockade used during anesthesia practice, in obese patients, considering that sugammadex is indicated in adults…
- Trial name
- NCT02568345
- Testing
- sugammadex ED90
- Volunteers
- 31 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Obesity
Brain-to-Society Diagnostic for Prevention of Childhood Obesity and Chronic Disease
This multi-national program applies a breakthrough approach to childhood obesity called, Brain-to-Society (BtS) Diagnostic Approach.
- Trial name
- NCT03151694
- Where
- 2 sites in Canada, India
- Volunteers
- 1,224 people, healthy volunteers welcome
- Sponsor
- McGill University
Ischemic Stroke
Ischemic Stroke, Obesity and Thrombolysis
This study focuses on the relationship between obesity and stroke, which are both characterized by increasing incidence and prevalence with epidemic proportions worldwide and tremendous socio-economic consequences.
- Trial name
- ISOT (NCT04196894)
- Where
- 2 sites in Switzerland
- Volunteers
- 280 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Childhood Obesity Prevention, Childhood Obesity
Postnatal Exercise to Activate Baby's Brown Fat
The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk.
- Conditions
- Childhood Obesity Prevention, Childhood Obesity, Physical Activity, Lactation
- Trial name
- PEABaBy (NCT07467694)
- Testing
- Active group
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Obesity, Cardiovascular Diseases
High-intensity Exercise Training or Multidisciplinary Treatment in Extremely Obese Adolescents
The aim of the present study was to determine the effects of a multidisciplinary approach and intensity-controlled interval training on cardiovascular risk factors in overweight adolescents
- Trial name
- NCT00682266
- Testing
- intensity controlled interval training (AIT), Multidisciplinary approach (MTG)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Overweight
Impact of Ashwagandha in Obesity Parameters from Mexican Adults
This clinical trial aimed to assess the impact of ashwagandha supplementation on serum lipid concentrations and body composition in Mexican adults with overweight and obesity.
- Trial name
- NCT06676605
- Testing
- Withania somnifera
- Where
- Mexico
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ivan Luzardo-Ocampo
Type 2 Diabetes Mellitus (T2DM), Overweight or Obese
A Study of BGM0504 in Healthy Participants and Participants With Impaired Renal Function
The purpose of this study is to assess how fast BGM0504 gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.
- Trial name
- NCT06929156
- Testing
- BGM0504
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Obesity
Quality of Life and Body Image in Women Underwent Thighplasty
Obesity is a chronic disease now considered a major public health concern in the global context, as it causes or exacerbates many diseases limitations in providing quality of life and higher treatment costs.
- Trial name
- NCT01453231
- Testing
- thighplasty
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Overweight, Obesity
Motivational Interviewing for Overweight and Obese Adults at Healthy Life Centers
Overweight and obesity are major public health problems associated with increased morbidity and mortality. Motivational interviewing is a patient-centered counseling approach that may improve lifestyle behaviors and weight…
- Trial name
- MI-HLC (NCT07745231)
- Testing
- Motivational Interviewing, Routine Nutrition Counseling
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Sakarya University
Type 2 Diabetes (T2DM), Obesity & Overweight
Optimizing Lifestyles Through Increased Vegetable-rich Eating Pilot Study
The goal of this pilot clinical trial is to examine how receipt of ingredients for a Mediterranean diet (with or without nutrition classes) impacts Type 2 Diabetes Mellitus risk factors among adults in the US South.
- Trial name
- OLIVE Pilot (NCT07509502)
- Testing
- Dietary Intervention Teaching Kitchen (TK) Classes, Food is Medicine Grocery Provision (FiM)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Pregnancies at Increased Risk for Excessive Gestational Weight Gain, Ecological Momentary Assessment and Intervention
Continuous Glucose and E-Monitoring to Support Healthy Weight Gain in Pregnancies - The GEM Study
This single-arm pilot study will evaluate the feasibility and acceptability of a remotely delivered behavioral lifestyle intervention, adapted from the SmartMoms framework, to promote health gestational weight gain in pregnant…
- Conditions
- Pregnancies at Increased Risk for Excessive Gestational Weight Gain, Ecological Momentary Assessment and Intervention, Continuous Glucose Monitor
- Trial name
- GEM (NCT06666257)
- Testing
- Continuous Glucose and E-Monitoring to Support Healthy Weight Gain in Pregnancy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Obesity
Safety and Pharmacokinetic Study of Y242 in Adult Subjects
Obesity causes 600 premature deaths per week in the UK and existing treatments are not effective. When humans eat, the bowels naturally secrete chemicals into the bloodstream which make people feel full and which stop eating.
- Trial name
- Y242-01 (NCT01515319)
- Testing
- Y242, 0.9% saline
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Imperial College London
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