Clinical trials: Obesity, Overweight
Cardiovascular Diseases, Obesity
Low Sodium Diet and Behavioral Intervention for Reversing Arterial Stiffening in Overweight Individuals
Obese individuals are at risk for developing cardiovascular disease (CVD). Increasing physical activity, losing weight, and reducing sodium intake may reverse arterial stiffness and blood vessel damage that is linked to obesity.
- Trial name
- SAVE (NCT00366990)
- Testing
- Low Sodium Diet, Regular Sodium Intake
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Type 2, Obesity
Genetic and Epigenetic Risk of T2D in the UAE
T2D is a global public health crisis and a threat to socioeconomic development of all nations, particularly in developing countries.
- Trial name
- NCT04270097
- Where
- United Arab Emirates
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Pregestational Obesity (BMI > 27kg/m2), History of Polycystic Ovary Syndrome
Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women
Gestational diabetes mellitus is one of the most frequent complications of pregnancy, that affect between 1 to 14% of population around the world.
- Trial name
- NCT01675310
- Testing
- medical nutrition therapy + metformin, Medical nutrition therapy
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Blood Pressure
Oral L-Citrulline and ADMA in Pregnancy
The purpose of this study is to determine if oral of L-citrulline (3 grams/day) for 3 weeks provided in mid-pregnancy to obese subjects will decrease the plasma ADMA/L-arginine ratio, lower maternal blood pressure, improve…
- Trial name
- NCT00743210
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Overweight or Obese Adults
Effect of a Liquid Tonic Drink on Post-meal Glucose and Insulin Responses
A randomised, double blinded, placebo-controlled crossover design clinical trial conducted at the Mary MacKillop Institute for Health Research (MMIHR, Australian Catholic University) for individuals with overweight/ obesity.
- Trial name
- NCT07030010
- Testing
- Breakfast meal challenge with tonic drink
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Australian Catholic University
Healthy
Probiotics to Improve Women's Health
The purpose of the study is explore the effect of probiotics on plasma lipopolysaccharides (LPS) concentrations, as well as insulin and glucose levels, in obese women prior to and after dietary challenges (high carbohydrate meal…
- Trial name
- NCT01800760
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Obesity
Effects of HMOs on the Faecal Microbiota and on Host Metabolism in Obese Children
The study is a randomised, placebo-controlled, double-blind, parallel study in obese children. A total of 75 obese children in the age 5 to 10 years, enrolled in a childhood obesity treatment program, will be included.
- Trial name
- NCT02786160
- Testing
- HMO, Dextropur
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Glycom A/S
Obesity, Exercise Reinforcement
Exercise and Weight Control
The objective of this project is to determine the biological, neurobehavioral, and behavioral compensatory responses to exercise training-induced energy deficits in overweight to obese men and women.
- Trial name
- NCT03413826
- Testing
- Exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Overweight and Obesity, Insulin Sensitivity
Does Hyperbaric Oxygen Therapy Lead to a Sustained Increase in Insulin Sensitivity?
In a recent series of studies performed by our group, we have shown that exposure to hyperbaric oxygen (HBOT) leads to an increase in insulin sensitivity in male subjects and that this improvement can be measured in all men, not…
- Trial name
- HOTAIR3 (NCT02136615)
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Obesity, Risk Factors
Motivational Interviewing to Promote Healthy Behaviours in Young Adults
The overall goals of this project are to evaluate the feasibility of web-based nurse-led motivational interviewing and educational interventions to promote healthy behaviours for obesity prevention and maintenance of healthy…
- Trial name
- Motivate (NCT05264740)
- Testing
- Motivational interviewing, Educational materials
- Where
- Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- McMaster University
Obesity, Morbid
Laparoscopic Sleeve Gastrectomy-Induced Decline in Plasma Asprosin and Its Association With Metabolic Recovery
the present study aimed to systematically assess the changes in plasma asprosin levels at 3, 6, and 12 months after LSG, to explore the relationships between asprosin dynamics and key metabolic parameters, including body mass…
- Trial name
- NCT07008274
- Testing
- surgery
- Where
- China
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Obesity, Morbid
Comparison of Two Types of Face Mask Ventilation in Obese Patients
Two types of face masks : cuffed and uncuffed were evaluated for artificial ventilation in obese patients. After induction to anesthesia patients were ventilated with both types of masks using anesthesia machine with the same…
- Trial name
- NCT06219460
- Testing
- Ventilation using two types of face masks
- Where
- Poland
- Volunteers
- 108 people
- Sponsor
- Medical University of Lodz
Cardiopulmonary Disease
SGA for TEE: Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease.
Increasingly, transesophageal echos (TEEs) are being done on high risk patients. A TEE is a short procedure done with deep sedation, but poses an increased risk of apnea/ hypoxemia in those with pulmonary disease.
- Trial name
- SGA-TEE (NCT04939220)
- Testing
- TEE with SGA, TEE with Deep Sedation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Physical Inactivity, Overweight and Obesity
A Pilot Factorial Trial of an Integrated Lifestyle Intervention
This study plans to learn more about the feasibility and acceptability of integrating the Move physical activity support program within an existing lifestyle intervention program.
- Trial name
- NCT06116435
- Testing
- Prevent T2, Move group-based classes, Fitness Membership
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity
Effect of Electroacupuncture on Obesity
The investigators describe a protocol for a randomized controlled trial to find out the effect and safety of electroacupuncture on losing weight in obese patients with prediabetes.
- Trial name
- NCT05237089
- Testing
- Electroacupuncture, Health education
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Type2 Diabetes, Obesity
mHealth Intervention for Older Adults
This is a pilot study to test the feasibility and acceptability of a self-regulation theory-based mHealth behavior intervention for overweight or obese older adults with T2DM.
- Trial name
- NCT03398590
- Testing
- self-regulation theory-based mHealth behavior intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Boston College
Autism Spectrum Disorder, Obesity
Mobile Health Intervention for Children With Autism
This study is a randomized clinical trial conducted in China from January 2023 to July 2025. It aims to test whether a mobile health program delivered via WeChat, with or without additional human support, can help improve body…
- Conditions
- Autism Spectrum Disorder, Obesity, Pediatric Overweight
- Trial name
- WeChat-Autism (NCT07514910)
- Testing
- Standard Lifestyle Recommendations, WeChat-Based Mobile Health Intervention, Coach-Facilitated Tele-Group Sessions
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Hunan Normal University
Obesity
Prebariatric Surgery Physical Exercise Training in Telehealth
The aim of our study is to evaluate the feasibility of a supervised training session using telehealth in the "Clinique medico-chirurgicale du traitement de l'obésité de Sherbrooke" (CMCTO) and its impact on health, physical…
- Trial name
- TelePreSET (NCT02083913)
- Testing
- Telehealth supervised exercise training
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Université de Sherbrooke
Obesity, Morbid
Randomized Controlled Trial of Fecal Microbiota Transplantation in Severe Obesity
This is a randomized, double-blinded and placebo controlled prospective trial with sixty patients to investigate the effect of fecal microbiota transplantation (FMT) on body weight in patients with severe obesity.
- Trial name
- RCTFMTOb (NCT03273855)
- Testing
- Fecal microbiota transplantation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital of North Norway
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