Clinical trials: Obesity, Overweight
Pediatric Obesity
Healthy Start to Increase Physical Activity and Improve Healthy Eating in Early Childcare Centres
Childhood obesity is one of the greatest challenges facing public health and recent evidence shows it begins in preschool aged children.
- Trial name
- NCT02375490
- Testing
- Healthy Start
- Where
- 2 sites in Canada
- Volunteers
- 897 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Prader Willi Syndrome, Obesity
Characterization of Transcriptional Regulators of Ghrelin Hormone Which Causes Genetic Obesity
The problem point of the Prader-Willi Syndrome (PWS) patient is the obesity which is intense and the plasma ghrelin level which increases unusual from the recently PWS patients was discovered.
- Trial name
- NCT01404624
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Obesity, Childhood
The Effect of Healthy Nutrition and Yoga Program on Obese Children
This study was planned to examine the effects of a healthy nutrition and yoga program given to obese children on nutritional behavior, physical activity and anthropometric measurements.
- Trial name
- NCT06265597
- Testing
- Healthy Nutrition and Yoga Program
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- TC Erciyes University
Nutritional Disorder
Evaluation of Micronutrients in Obese Patients
The aim of the study primarily was to investigate the value of zinc to copper ratio as possible biomarker of trace elements imbalance in morbidly obese subjects undergoing LSG.
- Trial name
- NCT04554082
- Testing
- laparoscopic sleeve gastrectomy
- Volunteers
- 107 people
- Sponsor
- Alexandria University
Obesity
Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults
Obesity adversely affects myocardial (muscular heart tissue) metabolism, efficiency, and diastolic function. The objective of this study was to determine if weight loss could improve obesity-related myocardial metabolism and…
- Trial name
- NCT00572624
- Testing
- Diet, Gastric bypass surgery
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
A Study to Investigate the Safety, Tolerability, Pharmacokinetic/Pharmacodynamic Characteristics, and Food Effect of HSG4112
1. Study Objective: The objective of this phase 1 clinical trial is to evaluate the safety, tolerability, pharmacokinetic/pharmacodynamic characteristics and food effect of HSG4112 after oral administration in healthy male…
- Trial name
- NCT04732988
- Testing
- HSG4112
- Where
- 2 sites in South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Glaceum
Mood, Stress
Walking Green: The Effects of Walking in Forested and Urban Areas
This research hypothesizes that moderate physical activity in a "green environment" (e.g. a forest preserve path) has increased benefits on psychological measures (stress, anxiety, mood, depression, attention) and on…
- Conditions
- Mood, Stress, Anxiety, Depression
- Trial name
- NUWG (NCT03950661)
- Testing
- Walking
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cardiovascular Diseases, Sarcopenic Obesity
A High-PRotein Mediterranean Diet and Resistance Exercise for Cardiac Rehabilitation
Cardiovascular disease is responsible for a quarter of all deaths in the UK and risk seems to be higher in cardiac rehabilitation (CR) with lower body weight which may be due to sarcopenci obesity (SO) or low muscle mass with…
- Trial name
- PRiMER (NCT04272073)
- Testing
- High-Protein Mediterranean Diet, Resistance Exercise, Standard Dietary Advice
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Liverpool John Moores University
Overweight and Obesity
A Study to Investigate the Safety and Efficacy of TE-8105 in Overweight or Obesity Participants
This is a Phase 2b, randomized, double-blind, placebo-controlled, multiple ascending dose study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and efficacy of TE-8105 in adults with overweight or obesity…
- Trial name
- NCT07857473
- Testing
- TE-8105 MAD Cohort 1, TE-8105 MAD Cohort 2, TE-8105 MAD Cohort 3
- Where
- 2 sites in Australia
- Volunteers
- 204 people
- Sponsor
- Immunwork, Inc.
Obesity
Balanced Propofol Sedation During Upper Endoscopy in Morbidly Obese Patients
The purpose of this study is to evaluate the safety of propofol-based, gastroenterologist-administered sedation in severely obese patients (BMI≥35) undergoing upper endoscopy.
- Trial name
- NCT00782873
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Research Associates of New York, LLP
Binge Eating Disorder, Obesity
Lamotrigine in the Treatment of Binge Eating Disorder Associated With Obesity
This research study is to evaluate the effectiveness, tolerability, and safety of lamotrigine therapy in the treatment of binge eating disorder associated with obesity.
- Trial name
- NCT00277641
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Lindner Center of HOPE
Breast Cancer, Obesity
Exergaming Intervention and Breast Cancer Biomarkers in Black Women
Overview: This is a 6 month, two-arm randomized clinical trial using comparing exergaming to a control group. The investigators will randomize Black sedentary overweight/obese women to Wii Fit exercise (n=50) or the control arm…
- Trial name
- POWER (NCT02152462)
- Testing
- Exergaming
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Georgetown University
type1diabetes, Hunger
Postprandial Gut Hormone Responses in Patients With Type 1 Diabetes Mellitus
The study will compare the postprandial responses to a test meal between subjects with type 1 diabetes and healthy control subjects, in terms of gut hormone levels, meal induced thermogenesis, hunger and satiety perception, as…
- Conditions
- type1diabetes, Hunger, Obesity
- Trial name
- NCT04430946
- Testing
- Standardized test meal
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
PCOS (Polycystic Ovary Syndrome), Obese Adolescents
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents
- Trial name
- Beef+ (NCT07780188)
- Testing
- Beef+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Obesity
Evaluation of an Enhanced Delivery Model for Go NAPSACC
This study will compare the effectiveness and cost of Basic and Enhanced delivery models for Go NAPSACC on child care centers' use of evidence-based nutrition and physical activity practices.
- Trial name
- NCT03938103
- Testing
- Enhanced Go NAPSACC, Basic Go NAPSACC
- Where
- 2 sites in United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Postoperative Bariatric Surgery
Lung Ultrasound Evaluation of the Effects of PEEP and Recruitment Strategies Adjusted for Intraoperative Dynamic Compliance on Postoperative Respiratory Complications in Obese Patients Planned for Laparoscopic Surgery
This study aims to investigate the effects of the personalized application of respiratory pressures applied to patients undergoing laparoscopic bariatric surgery when they are connected to a ventilator under general anesthesia…
- Conditions
- Obesity, Postoperative Bariatric Surgery, Laparoscopic Surgery, Individualized PEEP Treatment Strategy
- Trial name
- NCT06994780
- Testing
- dynamic compliance guided PEEP titration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Morbid Obesity
Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)
The investigators propose a randomized controlled trial comparing BP and roux limb lengths measuring 30 and 15% respectively of patient's total small bowel length versus current standard practice using fixed lengths.
- Trial name
- CLIMBII (NCT06293703)
- Testing
- Surgery
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Salvador Navarrete
Obesity
Does Obesity Influence Women Cardiorespiratory Fitness and Daily Physical Activities? (ACTIVOB)
Many obese individuals experience difficulties in executing household activities. In this study, we investigate the cardiorespiratory fitness (CRF) of obese vs.
- Trial name
- ACTIVOB (NCT03233061)
- Testing
- cardiorespiratory fitness and daily physical activities evaluations
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Laboratory of Movement, Condorcet, Tournai, Belgium
Obesity, Rapid Eating Style
Eating RePace Study
The aims of this study are to develop a novel family-based behavioral intervention (Re-Pace) to help children at risk for obesity (children who eat rapidly and have an overweight parent/legal guardian) develop a more normal…
- Trial name
- REPACE (NCT02186379)
- Testing
- RePace Intervention, Usual Care Control
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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