Clinical trials: Obesity, Severe
Obesity
Body Composition Outcomes in MS Patients
Objectives The objective of this project is to generate pilot data substantiating our hypothesis that advanced body composition measurement tools will provide more accurate and clinically relevant data on the outcomes of…
- Trial name
- BCOMS (NCT07530718)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Pennington Biomedical Research Center
Morbid Obesity
Nonsurgical Reversible Obesity Treatment (NROT1)
The present study relates to apparatus and methods that can be applied using non-invasive techniques for effectively reducing nutrient absorption in the small intestines of obese people.
- Trial name
- NROT1 (NCT05420506)
- Testing
- NROT1
- Volunteers
- 20 people
- Sponsor
- Yeditepe University
Obstructive Sleep Apnea
Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults
The purpose of this study is to test the effectiveness of two different weight loss diets on obstructive sleep apnea (OSA) severity.
- Trial name
- NCT02251574
- Testing
- Low Calorie Diet, Very Low Calorie Diet, Standard Care
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Opioid Use, Bariatric Surgery Candidate
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery.
- Conditions
- Opioid Use, Bariatric Surgery Candidate, TCI Eleveld, Obesity
- Trial name
- NCT07568938
- Testing
- opioid free anesthesia, Opiod Free Anesthesia with TCI ELEVELD
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Obesity
Signature Diagnostic of Non-alcoholic Steatohepatitis (NASH) by Infrared Light Spectroscopy
Evaluation of the diagnostic performance of an algorithm developed to detect metabolic profiles specific of non-alcoholic steatohepatitis NASH and based on the reading of a blood sample's infrared spectra
- Trial name
- SIGNALS (NCT03978247)
- Testing
- NASHMIR
- Where
- Belgium
- Volunteers
- 382 people
- Sponsor
- Diafir
Obesity, Morbid, Bariatric Surgery Candidate
Obesity Cohort : Medical Follow-up of Severe or Morbid Obese Patients Undergoing Bariatric Surgery
The aim of this cohort is to evaluate the follow-up of morbidly obese patients treated by several types of bariatric procedures.
- Trial name
- BAREVAL (NCT02310178)
- Testing
- Bariatric surgery
- Where
- France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Montpellier
GERD, Morbid Obesity
Management of Reflux After Sleeve Using Stretta
Gastroesophageal reflux disease (GERD) is a frequently seen entity after sleeve gastrectomy. Management of GERD after sleeve is difficult given limited treatment modalities.
- Trial name
- MaRSS (NCT02637713)
- Testing
- Stretta, Radiofrequency (RF) Energy to the LES (Stretta Procedure)
- Where
- 13 sites in United States
- Volunteers
- 5 people
- Sponsor
- Montefiore Medical Center
Morbid Obesity
Impact of Pyloric Injection of Magnesium Sulfate and Lidocaine Mixture on Outcome After Sleeve Gastrectomy
Postoperative nausea and vomiting is a common adverse effect after sleeve gastrectomy, mostly due to increased intragastric pressure.
- Trial name
- NCT03729505
- Testing
- Pyloric injection of magnesium sulfate and lidocaine mixture, Pyloric injection of saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Morbid Obesity
Evaluation of Endostapled Anastomoses for Laparoscopic Gastric Bypass (EEA-LGB)
Laparoscopic gastric bypass surgery is a common procedure being performed for the treatment of morbid obesity. The procedure consists of a creation of a small gastric pouch and rerouting the small bowel to bypass the stomach and…
- Trial name
- EEA-LGB (NCT00254072)
- Testing
- 3.5 mm vs 4.8 mm Stapler During Laparoscopic Gastric Bypass
- Where
- 6 sites in United States
- Volunteers
- 355 people
- Sponsor
- University of California, Irvine
Morbid Obesity, Non Alcoholic Steatohepatitis
Non Invasive Measurements of Fibrosis, Inflammation and Steatohepatitis in Morbidly Obese Patients
Abstract: Fatty liver most frequently corresponds to a fat overload of the liver. It is usually classified as alcoholic steatosis or non-alcoholic steatosis.
- Trial name
- FIRM (NCT01695083)
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Morbid Obesity
Laryngeal Masks for Bariatric Surgery
Obese people pose specific problems as far as the management of airway during surgery. The study aims to compare efficacy and safety of two LMA devices.
- Trial name
- NCT01724970
- Testing
- ProSeal, Supreme LMA
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Padova
Obesity
Surgical Treatment for Morbid Obesity by Sleeve Gastrectomy Versus Gastric Bypass
The aim of this study is to assess that the sleeve gastrectomy can improve the risk benefit than the gastric bypass
- Trial name
- SLEEVE (NCT00722995)
- Testing
- Sleeve gastrectomy, Gastric Bypass
- Where
- France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes, Morbid Obesity
Diabetes Remission After RYGBP and RYGBP With Fundus Resection
The goal of this randomized clinical trial is to evaluate glycemic control in patients with morbid obesity and type 2 diabetes after Roux-en-Y gastric bypass (RYGBP) and RYGBP with fundus resection.
- Conditions
- Type 2 Diabetes, Morbid Obesity, Bariatric Surgery
- Trial name
- NCT05854875
- Testing
- Laparoscopic Roux en Y gastric bypass, Laparoscopic Roux en Y gastric bypass with fundus resection
- Where
- Greece
- Volunteers
- 24 people
- Sponsor
- University of Patras
Morbid Obesity
Longitudinal Assessment of Bariatric Surgery
The goal of the LABS-1 study is to assess the short-term safety of bariatric surgery.
- Trial name
- LABS-1 (NCT00433810)
- Where
- 10 sites in United States
- Volunteers
- 5,102 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Atrial Fibrillation, Obesity
Effectiveness And Safety Of Oral Anticoagulants Among Obese Patients With Non-Valvular A-Fib In VA Patients With Medicare
The overall objective of this analysis is to understand patient characteristics, the use of treatment, and clinical outcomes among obese (overweight) and severely obese patients with non-valvular atrial fibrillation (NVAF) who…
- Conditions
- Atrial Fibrillation, Obesity, Anticoagulants
- Trial name
- NCT04681482
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 107,383 people
- Sponsor
- Pfizer
Carcinoma, Hepatocellular, Metabolic Syndrome
Liver Resection and Simultaneous Sleeve Gastrectomy for MS-HCC (LIRESS)
Hepatocellular carcinoma (HCC) related to metabolic syndrome (MS) as unique risk factor is gradually overpassing the more common viral and alcohol etiology, becoming a global health issue.
- Trial name
- LIRESS (NCT06060847)
- Testing
- Liver resection and simultaneous sleeve gastrectomy for HCC induced by metabolic syndrome, Liver resection for HCC induced by metabolic syndrome
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ospedale V. Fazzi
Morbid Obesity, Obesity
Optic Nerve Sheath Diameter Changes During Bariatric Surgery
This prospective clinical study aimed to evaluate the effects of pneumoperitoneum and patient positioning on intracranial pressure in patients undergoing bariatric surgery.
- Trial name
- NCT07662538
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Obesity & Overweight, Gestational Diabetes Mellitus in Pregnancy
Evaluation of Nutritional Interventions to Limit Gestational Weight Gain in Women With Class III Obesity (BMI >40)
Women with obesity who gain more weight than recommended during pregnancy are more likely to have problems such as cesarean delivery, diabetes in pregnancy, high blood pressure, and larger babies.
- Conditions
- Obesity & Overweight, Gestational Diabetes Mellitus in Pregnancy, Gestational Weight Gain, Morbid Obesity
- Trial name
- OPTIMAL (NCT07828743)
- Testing
- Nutrition education
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Morbid Obesity
Study of Weight Loss Using Gastric Stimulation in Obese Patients
The purpose of this study is to test the effect of an implanted device that stimulates the stomach to help obese patients lose weight.
- Trial name
- SHAPE (NCT00200083)
- Testing
- Transcend II Model 8848
- Where
- 8 sites in United States
- Volunteers
- 190 people
- Sponsor
- MedtronicNeuro
Morbid Obesity
Transmitted Light Tissue Thickness Analysis (TiLTT)
To assess gastric wall thickness using transmitted light intensity.
- Trial name
- TiLLT (NCT02749201)
- Testing
- Gastrisail
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Maimonides Medical Center