Clinical trials: Obesity, Unspecified
Obesity
CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users
This study aims to assess the impact of GLP-1 receptor agonists, semaglutide and tirzepatide, on food cravings and diet quality in individuals with overweight or obesity.
- Trial name
- NCT06467604
- Testing
- Surveys, Indirect Calorimetry, Body composition
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Diabetes Mellitus, Obesity
Surgical Techniques in Diabetes Mellitus-II and Obesity. Metabolic Surgery Study (MSS)
The aim of this study is to compare clinical and laboratory findings of three surgical techniques in metabolic surgery in patients with type II diabetes mellitus and obesity (BMI> 30).
- Trial name
- MSS (NCT02310555)
- Testing
- Gastric bypass, Modified gastric bypass., Slevee Gastrectomy
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Obesity and Overweight
A First-in-human Study of HCR-188 in Overweight or Obese Otherwise Healthy Volunteers Without Type 2 Diabetes
This is a first-in-human study evaluating the safety, tolerability, pharmacokinetics, immunogenicity and pharmacodynamics of single and multiple doses of HCR-188 administered as subcutaneous injection(s).
- Trial name
- NCT06845943
- Testing
- HCR-188
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Helicore Biopharma, Inc.
Menopause Surgical, Estrogen Deficiency
Understanding the Roles of Hormones in Adipocyte Remodeling Following Menopause
The overarching aims of this study are to: 1. Characterize the rate of in vivo adipogenesis, and changes in adipose tissue gene and protein expression, in the scABD and scFEM depots of women undergoing surgical menopause (↓E2…
- Conditions
- Menopause Surgical, Estrogen Deficiency, Adiposity, Follicle-Stimulating Hormone Deficiency
- Trial name
- RESUME-2 (NCT03856268)
- Testing
- 'Surgical Menopause' Group, 'Drug-Induced Menopause' Group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Overweight, Obesity
Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
Dietary protein is a key element of most effective weight loss regimens. This study will investigate the effects of consuming soy protein on body composition and cardiometabolic health within the context of an effective weight…
- Conditions
- Overweight, Obesity, Weight Loss
- Trial name
- NCT02380963
- Testing
- Colorado Diet with soy protein foods., Colorado Diet with monetary payments
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Weight Management in Adult Patients With Obesity or Overweight
Phase I Study of XTL6001 Injection in Healthy and Obese Subjects
This is a multicenter, randomized, double-blind, placebo-controlled Phase I study to evaluate safety, PK and PD of single ascending dose (SAD) and multiple ascending dose (MAD) of XTL6001 injection in healthy and obese adult…
- Trial name
- NCT07205432
- Testing
- XTL6001
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shanghai Xitaili Biomedicine Technology co., Ltd.
Cardiovascular Diseases
Web-based Physical Activity Intervention to Promote Physical Activity
In this study insufficiently active adults with obesity will be assigned to either the Physical Activity for The Heart (PATH) intervention or an attention control group.
- Trial name
- NCT05803304
- Testing
- PATH Intervention, Attention Control Intervention, Physical activity tracker
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Osteoarthritis, Overweight and Obesity
Fit and Strong! Plus Comparative Effectiveness Trial
This randomized controlled trial is comparing outcomes of customary Fit and Strong!, to Fit and Strong! Plus, an enhanced version of the program that incorporates weight management.
- Trial name
- NCT03180008
- Testing
- Fit and Strong!, Fit and Strong! Plus
- Where
- United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Healthy, Obesity
A Study in Healthy People or Otherwise Healthy With Overweight or Obesity to Compare 2 Formulations of Survodutide Given in Different Ways, Either as a Pre-filled Syringe or a Pen-like Injector
The goal of this study is to find out whether different formulations of survodutide given by different delivery methods is taken up in the body in a similar way. Participants visit the study site regularly.
- Trial name
- NCT07413913
- Testing
- Survodutide formulation A, Survodutide formulation B2
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Obesity, Type 2 Diabetes
Probiotics as a Novel Approach to Modulate Gut Hormone Secretion and Risk Factors of Type 2 Diabetes and Complications
The investigators aim to test the hypothesis that Lactobacillus Reuteri-enriched microbiota improves insulin sensitivity and glucose tolerance in obese healthy and obese type 2 diabetes patients by improving gut hormone secretion…
- Trial name
- NCT01250106
- Testing
- Lactobacillus reuteri
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Weight Loss, Weight Gain
Eating Mindfully to Prevent Weight Regain
The overall objective of this study is to evaluate the efficacy of a mindfulness-based intervention to prevent weight regain in weight-reduced adults.
- Conditions
- Weight Loss, Weight Gain, Eating Behavior, Obesity
- Trial name
- EMPWR (NCT04847843)
- Testing
- Mindfulness Orientated Recovery Enhancement, Control Intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity, Inflammation
Anti-Inflammatory Activities of Grapes in Humans at Risk for Cardiovascular Disease
The goal of the study is to determine whether grape consumption can reduce the risk of cardiovascular disease by reducing the presence of inflammatory molecules and positively altering cholesterol levels, lipid profiles, and…
- Trial name
- NCT01443884
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Obesity & Overweight, Pediatric Obesity
Ultrasound Assessment of Tongue Characteristics in Children and Adolescents With Obesity
This longitudinal observational study aims to validate ultrasound-based tongue markers related to tongue characteristics, including fat accumulation, morphologic and mechanical properties of the tongue in children and adolescents…
- Conditions
- Obesity & Overweight, Pediatric Obesity, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07370350
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Child Health, Child Behavior
Children's Cooperation Denmark: a 3-year System Dynamics Trial
Lack of physical activity (PA) and sedentary lifestyle in Danish children is a major challenge. New strategies are needed to combat this development.
- Conditions
- Child Health, Child Behavior, Physical Inactivity, Child Obesity
- Trial name
- Child-COOP (NCT06185413)
- Testing
- Participatory system dynamics approach
- Where
- 5 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Obesity, Childhood, Overweight, Childhood
Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function
The investigators aim to assess the relationship between overweight/obesity and decreased cognitive function in adolescents. While this relationship has been seen in past literature, the causal mechanisms are still unclear.
- Trial name
- NCT04346433
- Testing
- Restricted Sleep, Adequate Sleep
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Self-Perception, Body Weight
Effects of Active Video Games in Physically Inactive Children
Inactivity was reported to be high in children and considered to be the fourth common cause of death in all ages. The reason for children is usually the increasing indoor use of sedentary screen time.
- Trial name
- AVGAME (NCT03720938)
- Testing
- Active Video Games
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Obesity, Weight Gain
Evaluation of the Efficacy of the Watch Your Weight During Holidays Program for the Prevention of Body Weight Gain in Mexican Adults.
Obesity is the main risk factor for the development of chronic-degenerative diseases in Mexico. Due to the difficulty of treating obesity, prevention is urgently needed.
- Conditions
- Obesity, Weight Gain, Overweight
- Trial name
- NCT05580926
- Testing
- Watch your Weight During Holidays, Control Group (minimal intervention)
- Where
- Mexico
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rolando Giovanni Díaz Zavala
Weight Loss, Time Restricted Feeding
TRE: Microbiome, Metabolic Health and Bone
In the Time-Restricted Eating: Microbiome and Bone (TREMBO) study, the primary goal is to determine the effect of time-restricted eating with caloric restriction compared to caloric restriction alone on bone health, as well as…
- Conditions
- Weight Loss, Time Restricted Feeding, Bone Loss
- Trial name
- TREMBO (NCT05548517)
- Testing
- Time Restricted Eating (TRE), Calorie Restriction
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Overweight and Obesity
Effects of Exercise Intensity on Energy Intake, Appetite and Enjoyment in Overweight and Obese Females
Interval exercise involves short bouts of high intensity exercise interspersed with periods of lower intensity exercise. The benefit is that a shorter total duration of exercise may be required to achieve cardiovascular benefits…
- Trial name
- NCT04437550
- Testing
- Exercise
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ohio University
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