Clinical trials: Obesity/Therapy
Obesity; Drug
The Effect of Weekly Semaglutide Treatment on Energy Expenditure
This study will test the effects of weekly injections of the glucagon like peptide-1 (GLP-1) agonist semaglutide on energy expenditure and metabolic parameters in a 24 week double-blind, placebo-controlled dose escalation…
- Trial name
- NCT06390501
- Testing
- Semaglutide
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Pediatric Obesity
VALÉ: A Multidisciplinary Childhood Obesity Treatment Program for Latino Communities
This proposal aims to test the initial feasibility and efficacy of a 10-week multidisciplinary pediatric weight management program among low-income Latino children, aged 5 to 11 years, from the Woodbridge, VA area.
- Trial name
- VALÉ (NCT04677582)
- Testing
- Vidas Activas, famiLias saludablEs (VALE)
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- George Mason University
Stress, Irritable Bowel Syndrome
Evaluating and Treating Potential Research Participants With Digestive Disorders
Background: Some research studies focus on digestive disorders, such as nutritional, gastrointestinal, and liver disorders. Researchers want to examine and treat people with digestive disorders in order to learn more about these…
- Conditions
- Stress, Irritable Bowel Syndrome, Obesity, Abdominal Pain
- Trial name
- NCT01736280
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Obesity, Type 2 Diabetes
Hyperbaric Oxygen Therapy and Insulin Resistance (HOTAIR2) - Effect of One HBO Session.
Obesity is an epidemic in Western society and is the biggest risk factor for insulin resistance and type 2 diabetes. The investigators have recently shown that exposure to hyperbaric oxygen (HBO) leads to an increase insulin…
- Trial name
- HOTAIR2 (NCT02009813)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Australia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Obesity, Weight Loss
Optimizing Self-Monitoring Feedback for the Treatment of Obesity
Self-monitoring (of weight, intake, and activity) is a core component in evidence-based lifestyle interventions for obesity. Research has shown that interventionist feedback increases adherence to self-monitoring and improves…
- Trial name
- NCT06508580
- Testing
- Component 1: Calorie Goal Attainment, Component 2: Diet Quality, Component 3: Physical Activity Goal Attainment
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity, Overweight
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese Individuals
Background: Sticking to a diet plan can be difficult, but is important for many different health reasons. Some people seem to have a harder time following and sticking to a diet plan than others.
- Trial name
- NCT01862796
- Testing
- Underfeeding diet, Weight maintaining diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Binge Eating
Treatment of Obesity and Binge Eating: Behavioral Weight Loss Versus Stepped Care
This controlled study will test the effectiveness of a stepped-care approach to a standard behavioral weight loss treatment for obese patients with Binge Eating Disorder (BED).
- Trial name
- NCT00829283
- Testing
- Behavioral Weight Loss, Behavioral Weight Loss + Guided self-help Cognitive-behavioral Therapy, Sibutramine/Orlistat
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Weight Loss
Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis
Obesity is an epidemic in the US. With progression of obesity, Nonalcoholic steatohepatitis (NASH) has been a growing public health issue.
- Conditions
- Obesity, Weight Loss, Body Weight, Nonalcoholic Steatohepatitis
- Trial name
- NCT02933554
- Testing
- Embospheres Microspheres
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Keith Pereira, MD:
Obesity, Mood Disorders
Psychosocial Intervention for Women With Mood Disorders Seeking Treatment for Obesity
Women with mood disorders are vulnerable to the negative consequences associated with obesity, and face considerable challenges with adherence to behavioral weight management interventions.
- Trial name
- NCT03743844
- Testing
- Compassion-focused psychoeducation group
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Obesity, Overweight
Response Evolution Chart
This study evaluates patient response to a motivation evolution chart for a medical-nutrition intervention as a continuation of a previous study: adherence to an overweight and obesity treatment available at…
- Conditions
- Obesity, Overweight, Motivation, Adherence, Patient
- Trial name
- NCT03484637
- Testing
- Lifestyle-medicine intervention
- Where
- Colombia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- BiomediKcal
Menopause, Perimenopause
Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women
The purpose of this study is to integrate Traditional Chinese Medicine (TCM) theory and therapeutic methods with modern low-level laser stimulation on corresponding acupoints, applying this combined approach to the field of…
- Conditions
- Menopause, Perimenopause, Obesity, Overweight
- Trial name
- NCT07472881
- Testing
- Multi-acupoint low-level laser therapy, Diet and exercise guidance
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Puberty, Precocious, Adiposity
Long-term Outcome of GnRH Analogues Treatment of Children With Idiopathic Central Precocious Puberty
This study evaluates the influence of early adiposity rebound, genetic polymorphisms and GnRHa treatment on long-term outcome of girls with idiopathic central precocious puberty.
- Trial name
- NCT02790112
- Testing
- GnRHas
- Where
- Belgium
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Obesity
Elements Vital to Treat Obesity Study
The overall objective of this study is to evaluate the first rigorously optimized, remotely delivered treatment for obesity against the current gold standard treatment in a head-to-head randomized controlled trial.
- Trial name
- EVO (NCT04708769)
- Testing
- Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP)
- Where
- United States
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Overweight, Obesity
The Healthy Weight for Life Program
This study is a randomized controlled pilot of a work site weight control intervention. The purpose of the pilot is to obtain preliminary data for future NIH submissions.
- Conditions
- Overweight, Obesity, Compliance Behavior
- Trial name
- HWL (NCT01470222)
- Testing
- Weight loss intervention
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Tufts University
Overweight and Obesity
Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease
The purpose of this study is to find out how the amount of fat or sugar in a person's diet, or the number of meals eaten each day, affect the amount of fat that people's bodies make, the types of fats in the bloodstream, and how…
- Trial name
- NCT02075710
- Testing
- High sugar/meal feed, High sugar/nibble, High fat/meal feed
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight, Obesity
Study to Promote Physical Activity Among Overweight Persons
Recent research suggests that overweight persons who are physically active may be significantly less likely to develop health complications and less likely to die early when compared even with lean persons who are not physically…
- Trial name
- NCT00313040
- Testing
- Brief Consultation with Health Counselor, workbook, Usual Care wait list
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
ADHD, Weight Loss
Obesity Treatment Enhanced With Working Memory Training
This study will examine the effects of providing subjects who have attention deficits, with or without a formal diagnosis of attention deficit hyperactivity disorder (ADHD), with Working Memory computerized training and explore…
- Trial name
- Focus (NCT02529397)
- Testing
- Adaptive Working Memory Training, Non-adaptive cognitive training
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Pulmonary Atelectasis, Respiratory Tract Diseases
Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery
The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01786681
- Testing
- Positive pressure
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Pediatric Obesity, Weight Loss
Our Lifestyles Our Lives
The purpose of the study was to examine the influence of step goals with pedometers to improve children's weight loss, physical activity, and psychosocial health during behavioral treatment.
- Trial name
- OLOL (NCT02965729)
- Testing
- Family-based weight management, Pedometer, Individualized step goals
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Weight Loss
Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity
The overall objective of the proposed research is to use an innovative methodological framework, the Multiphase Optimization Strategy (MOST), to design, for the first time, an optimized, scalable version of a technology-supported…
- Trial name
- Opt-IN (NCT01814072)
- Testing
- 12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician
- Where
- United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Northwestern University