Clinical trials: Obesity; Overweight
Obesity & Overweight
Evaluation of a Mobile Wellness Application and Wearable Fitness Tracker on Weight Management and Health Outcomes
This randomized controlled trial aims to evaluate the effectiveness of a mobile wellness application, both alone and in combination with a wearable fitness tracker, for supporting weight management, physical activity, and mental…
- Trial name
- NCT07463144
- Testing
- App + Fitness Tracker, App Only, Control Group
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- BetterMe Limited
Overweight/Obesity, Puberty
Improving Health Among Disadvantaged Girls to Slow Pubertal Onset and Reduce Long-term Health Risks
This study is testing whether improving health in girls during the prepubertal period may slow the onset of puberty. This study will focus on prepubertal girls who have a high weight status (at or above the 85th percentile for…
- Conditions
- Overweight/Obesity, Puberty, Health Behavior, Cardiometabolic Health
- Trial name
- NCT07460544
- Testing
- Family-Based Treatment (FBT)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Washington
Overweight/Obesity, Metabolic Syndrome
Effects of Cranberry on Gut and Metabolic Health
The consumption of plant-based foods, particularly berries, has been associated with improved health due to their high content of bioactive compounds.
- Conditions
- Overweight/Obesity, Metabolic Syndrome, Insulin Resistance, Microbiota
- Trial name
- CRANOS (NCT07460856)
- Testing
- Cranberry beverage
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Laval University
Hedonic Hunger, Mindful Eating Intervention
Effect of a Mindful Eating Education Program on Mindful Eating, Hedonic Hunger, and Anthropometric Measures in Obese Individuals With High Hedonic Hunger
The aim of this clinical trial is to evaluate the effect of mindful eating training on mindful eating behaviors and hedonic hunger levels in adults with obesity.
- Conditions
- Hedonic Hunger, Mindful Eating Intervention, Obesity & Overweight
- Trial name
- NCT07461740
- Testing
- Mindful eating training
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- TC Erciyes University
Alzheimer Disease (AD), Cardio Vascular Disease
Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)
The Arlington Longitudinal Optimal Healthy Aging (ALOHA) Study is a community-based research project led by the Marymount University Center for Optimal Aging (MCOA).
- Conditions
- Alzheimer Disease (AD), Cardio Vascular Disease, Mild Cognitive Impairment (MCI), Frailty Syndrome
- Trial name
- ALOHA (NCT07180147)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Marymount University
Body Weight, Obesity & Overweight
Breastmilk and the Link to Overweight/Obesity and Maternal Diet in the Mother-breastmilk-child Triad
The prospective 5-month follow-up study will involve 150 mother-infant dyads grouped based on maternal baseline BMI category (normal weight, overweight, obesity).
- Conditions
- Body Weight, Obesity & Overweight, Human Milk/Breastfeeding, Body Composition
- Trial name
- BLOOM-Triad (NCT07457515)
- Where
- 4 sites in Canada, Poland
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Warsaw University of Life Sciences
Obesity & Overweight, Healthcare Worker
Personalized Nutrition Coaching for a Weight Loss Program Among Overweight and Obese Nurses
Obesity among healthcare workers has become an increasing public health concern, with potential consequences for work productivity, quality of care, and long-term health outcomes.
- Conditions
- Obesity & Overweight, Healthcare Worker, Low Physical Activity Level
- Trial name
- NCT07440979
- Testing
- Personalized Nutrition Coaching
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Obesity & Overweight
Cardiac Function and Biomarkers in Patients With Obesity and Overweight
Obesity is a major public health problem worldwide and an established risk factor for cardiovascular disease. In individuals with obesity or overweight, systemic inflammation and endothelial dysfunction contribute to myocardial…
- Trial name
- BEYOND (NCT07455630)
- Testing
- Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- TecSalud Investigación Clínica
Obesity & Overweight, Obesity (Disorder)
Weight Loss and Adipose Tissue Metabolism During Conservative Treatment of Obesity
This prospective observational study investigates weight loss and metabolic changes in adults with obesity undergoing standard clinical diet-induced lifestyle treatment and counseling.
- Trial name
- 4FAT (NCT07456124)
- Testing
- Diet-Induced Weight Loss Program
- Volunteers
- 22 people
- Sponsor
- University of Helsinki
Obesity and Overweight, Nutrition
CHIME: Comparing Health Interventions for Maternal Equity
The goal of this comparative effectiveness trial is to compare how three different approaches to overcome barriers to resources and provide nutrition and physical activity counseling improve maternal healthy weight in pregnancy…
- Conditions
- Obesity and Overweight, Nutrition, Chronic Disease, Diabetes
- Trial name
- CHIME (NCT06724172)
- Testing
- Self-Management, Community-Based
- Where
- 4 sites in United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity & Overweight
Safety and Tolerability of a Nutritional Formula Designed to Aid in Maintenance of Muscle During Periods of Caloric Restriction in Adults
Muscle loss during caloric restriction is a significant concern for metabolic health and physical function, yet there is limited evidence on interventions that simultaneously target multiple contributing pathways.
- Trial name
- Redefine (NCT07447843)
- Testing
- Redefine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Nature's Sunshine Products, Inc.
Overweight and Obesity, Attention-Deficit Hyperactivity Disorder
Families, Responsibility, Education, Support, and Health for Executive Function
The pilot study will be a one group open-label treatment program and will be used to refine a parent-based behavioral treatment enhanced with executive-function training (PBT-EF) for children with comorbid overweight or obesity…
- Trial name
- FRESH-EF (NCT05165511)
- Testing
- PBT-EF
- Where
- United States
- Sponsor
- University of California, San Diego
Type 2 Diabetes, Hypertension
PILI 'Āina Household
Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic…
- Conditions
- Type 2 Diabetes, Hypertension, Dyslipidemias, Overweight and Obesity
- Trial name
- NCT06526273
- Testing
- PILI 'Āina, Control
- Where
- 2 sites in United States
- Volunteers
- 210 people
- Sponsor
- University of Hawaii
Type 2 Diabetes, Hypertension
'Ai Pono Cooking Demonstrations
Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic…
- Conditions
- Type 2 Diabetes, Hypertension, Dyslipidemias, Overweight and Obesity
- Trial name
- NCT06526650
- Testing
- 'Ai Pono
- Where
- 2 sites in United States
- Volunteers
- 1,780 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Obesity &Amp;Amp; Overweight, Gastric Emptying Time
Observational Study on GER in Patients With Simple Obesity
Dear Patients, The investigators invite participants to take part in an observational study on gastric emptying rate in individuals with simple obesity.
- Conditions
- Obesity &Amp;Amp; Overweight, Gastric Emptying Time, Type2 Diabetes Mellitus
- Trial name
- NCT07188571
- Testing
- Gastric emptying scintigraphy
- Where
- China
- Volunteers
- 163 people
- Sponsor
- Jing Ma
Overweight , Obesity
Study on the Efficacy of Probiotics in the Treatment of Childhood Obesity and Their Effects on Gut Microbiota
This interventional study aims to evaluate the efficacy of a probiotics supplementation (Bifidobacterium longum subsp. longum Dipro-O and Bifidobacterium longum subsp.
- Trial name
- NCT07448220
- Testing
- Probiotic
- Where
- 2 sites in China, Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Min-Tze LIONG
Obesity & Overweight
Precision Lifestyle Intervention and Anthropometric, Nutritional, and Metabolic Health Outcomes
This clinical trial aims to recruit a core cohort of adults with normal weight, overweight, and obesity, but without other metabolic alterations, to undergo a six-month nutritional intervention.
- Trial name
- MAR-GEN (NCT07450066)
- Testing
- Diet
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Obesity, Weight Change Trajectory
Evaluation of the Safety and Efficacy of Revita® DMR on Body Weight Maintenance in Subjects With Obesity Who Have Achieved at Least 15% Weight Loss on Tirzepatide
Fractyl is evaluating Revita Duodenal Mucosal Resurfacing (DMR) in the REMAIN-1 pivotal study, which is designed to include two cohorts - an open label cohort referred to as REVEAL-1, and a randomized cohort, which includes both…
- Conditions
- Obesity, Weight Change Trajectory, Weight Change, Body
- Trial name
- REMAIN-1 (NCT06484114)
- Testing
- Revita Duodenal Mucosal Resurfacing (DMR)
- Where
- 32 sites in United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Fractyl Health Inc.
Glucocorticoids, Obesity and Overweight
Acute Effects of Ultra-processed Versus Unprocessed Foods on Glucocorticoid Secretion in Healthy Individuals
The investigators aim to understand whether the acute cortisol response to food differs between differently processed foods. In this monocentric, randomized, cross-over, open-label study, 20 healthy volunteers will receive two…
- Conditions
- Glucocorticoids, Obesity and Overweight, Food Effect
- Trial name
- UltraCort (NCT06724692)
- Testing
- Ultra-processed breakfast, Low-processed breakfast
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eleonora Seelig
Type 2 Diabetes
A Feasibility Study of Optimal Non-Pharmacological Lifestyle Modifications in People With Type 2 Diabetes
The overall aim of this study is to examine the feasibility of a 12-month, two-arm lifestyle intervention to induce and maintain remission of type 2 diabetes (T2D).
- Trial name
- ON LiMiT (NCT07262788)
- Testing
- CH-rich diet with exercise, CH-reduced diet with exercise
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Steno Diabetes Center Copenhagen