Clinical trials: Obesity; Overweight
Brain Care Score, Exercise
An Exercise Intervention to Improve Overall Brain Health
The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a…
- Conditions
- Brain Care Score, Exercise, Hypertension, BMI
- Trial name
- NCT06035094
- Testing
- Exercise Intervention to improve overall Brain Health
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Overweight (BMI > 25), Obese But Otherwise Healthy Participants
Pistachio Snacking and Metabolic Flexibility
The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults.
- Conditions
- Overweight (BMI > 25), Obese But Otherwise Healthy Participants, Overweight or Obese, Obese Patients (BMI ≥ 30 kg/m²)
- Trial name
- NCT07340125
- Testing
- Pistachio
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Obesity, Morbid, Obesity and Overweight
The Effect of Laparoscopic Sleeve Gastrectomy on Blood Phoenixin-14 Levels
Obesity is a major global health concern with a rising prevalence and numerous associated comorbidities. For the treatment of severe obesity, bariatric surgery stands as the most effective procedure.
- Trial name
- Morbid Obesity (NCT07004556)
- Testing
- Preoperative blood sampling for determining Phoenixin 14 levels, Postoperative blood sampling for determining Phoenixin 14 levels
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Obesity & Overweight, Sleeve Gastrectomy
Istmin Levels in Laparoscopik Sleeve Gastrectomy
Obesity is a multifactorial disease which has become a public health problem with increasing frequency, especially in recent years.
- Conditions
- Obesity & Overweight, Sleeve Gastrectomy, Adipokines
- Trial name
- NCT07335549
- Testing
- Preoperative Serum Isthmin Levels, Postoperative Third Month's Serum Isthmin Levels, Preoperative BMI
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Metabolic Syndrome, Obesity & Overweight
Effect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based Therapy
We investigate the role of empagliflozin in the treatment of obesity in PLWH.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, HIV (Human Immunodeficiency Virus)
- Trial name
- NCT07336797
- Testing
- Empagliflozin (oral)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Abdelrahman Mahmoud
Overweight
Promotion of Weight Management
The identification of intermittent fasting as an alternative method to traditional weight maintenance protocols could have a significant impact on preventing body weight regain common after successful weight loss, and potentially…
- Trial name
- POWER-VET (NCT04131647)
- Testing
- Weight Maintenance, Weight Maintenance + Intermittent Fasting
- Where
- 2 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obesity, Maternal, Hypertension in Pregnancy
Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children
This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on postpartum mothers and infants.
- Conditions
- Obesity, Maternal, Hypertension in Pregnancy, Hypertension, Pregnancy-Induced, Diabetes
- Trial name
- NCT05473767
- Testing
- Family Check Up Heart, Family Check-Up
- Where
- 3 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of Pittsburgh
Obesity &Amp;Amp; Overweight
The Role of Empathy in the Links Between Binge Eating Disorder and Interpersonal Difficulties
Obesity, recognized as a chronic disease by the WHO since 1998, affects 22.1% of adults in the Hauts-de-France region. Beyond the physiological aspects, it is associated with psychological difficulties, particularly eating…
- Trial name
- EMBED_OB (NCT07201662)
- Testing
- Condensed and Revised Multifaceted Empathy Test, Hospital Anxiety and Depression Scale, Interpersonal Reactivity Index
- Where
- France
- Volunteers
- 155 people
- Sponsor
- Clinique de la Mitterie
Malnutrition, Nutritional Risk
Nutrition Support on Outcomes and Cost-effectiveness for Patients at Risk
1. The aim of this large scale study to survey the prevalence of nutritional risk and malnutrition in China,Europe and USA. 2. The impact of nutritional support for the patients at nutritional risk on clinical outcomes and…
- Trial name
- NCT00289380
- Where
- 15 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Peking Union Medical College
Obesity or Overweight
A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose Weight
This study will look at how well the new medicine CagriSema helps people with excess body weight losing weight compared to a "dummy" medicine and a medicine called semaglutide.
- Trial name
- REDEFINE 6 (NCT05996848)
- Testing
- Cagrilintide, Semaglutide
- Where
- 37 sites in China
- Volunteers
- 300 people
- Sponsor
- Novo Nordisk A/S
Overweight and Obesity
A Study to Investigate the Safety and Tolerability of TE-8105 in Overweight/Obese Participants Without Diabetes
This is a Phase 1/2a, first-in-human, prospective, open-label study to evaluate the safety, tolerability, PK, PD, and effect on body weight of TE-8105 in overweight/obese participants without diabetes.
- Trial name
- NCT06471530
- Testing
- TE-8105 SAD Cohort 1, TE-8105 SAD Cohort 3, TE-8105 SAD Cohort 5 (Adaptive cohort)
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Immunwork, Inc.
Obesity and Overweight
Comparision of Aerobic Exercise to Aerobic Plus Yoga Exercise for Weight Loss in Adults With Overweight or Obesity.
The goal of this clinical trial is to learn whether adding yoga exercise to a behavioral weight loss intervention improves weight loss in adults with overweight or obesity.
- Trial name
- NCT06636773
- Testing
- Diet, Aerobic Exercise, Behavioral Sessions
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- University of Kansas Medical Center
Obesity & Overweight
A Study of SGB-7342 in Subjects With Obesity or Overweight
The purpose of this study is to evaluate the safety and tolerability of subcutaneously administered SGB-7342 in adult subjects with obesity and overweight.
- Trial name
- NCT07324850
- Testing
- SGB-7342
- Volunteers
- 45 people
- Sponsor
- Suzhou Sanegene Bio Inc.
Metabolic Syndrome, Obesity & Overweight
Breath Mass Spectrometry in Metabolic Syndrome and Metabolically Healthy Obesity
This study aims to develop a non-invasive diagnostic method for metabolic syndrome (MetS) and metabolically healthy obesity (MHO) through analysis of exhaled air.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, Metabolically Healthy Obesity
- Trial name
- NCT07330297
- Testing
- Breath Sampling and Analysis by PTR-MS
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Healthy Subjects, Lean Trained Subjects
Training Effects on Fuel Metabolism
The investigators are interested in how skeletal muscle processes fat and how this may affect insulin resistance. This is an important question since insulin resistance predates and predicts type 2 diabetes.
- Conditions
- Healthy Subjects, Lean Trained Subjects, Overweight and Obesity
- Trial name
- TrainMeUpMN (NCT02150889)
- Testing
- Running Program, Yoga Program
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Overweight, Obesity
A Study of How CagriSema Works on Appetite in People With Excess Body Weight
Part A: The study will look at participants appetite and energy intake and also look at the mechanisms of brain associated with appetite and food intake.
- Trial name
- NCT06267092
- Testing
- No treatment given, Cagrilintide and Semaglutide
- Where
- Germany
- Volunteers
- 164 people
- Sponsor
- Novo Nordisk A/S
Obesity
A Study to Evaluate AMG 133 in Chinese Participants With Obesity or Overweight
The main objective of the study is to assess the pharmacokinetics (PK) of Maridebart Cafraglutide after a single subcutaneous (SC) administration in overweight or obese Chinese participants.
- Trial name
- NCT06352892
- Testing
- Maridebart Cafraglutide
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Amgen
Severe Mental Disorder, Metabolic Complication
Effectiveness of a Pragmatic, Metabolic Care Clinic for Patients With Severe Mental Illness - The Meta Care Clinic
This study will examine the effectiveness of a Pragmatic, Metabolic Care Clinic for Patients With Severe Mental Illness
- Conditions
- Severe Mental Disorder, Metabolic Complication, Side-Effect;Medication, Schizophrenia Spectrum and Other Psychotic Disorders
- Trial name
- NCT06624462
- Testing
- Treatment in the Meta Care Clinic, Standard care with general practitioner and/or outpatient clinics
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Bjorn H. Ebdrup
Adolescents With Obesity or Overweight With Weight-Related Comorbidities
A Study of IBI362 in Chinese Adolescents With Obesity or Overweight
The study is designed to assess the efficacy and safety of multiple doses of IBI362 in Chinese adolescent subjects with obesity or overweight.
- Trial name
- NCT07255209
- Testing
- IBI362
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Obesity &Amp;Amp; Overweight, Bariatric Surgery
EFFECTS OF SUPERVISED PHYSICAL EXERCISE AFTER BARIATRIC SURGERY ON MUSCLE MASS AND BONE DENSITY (OBEFIT STUDY)
CLINICAL TRIAL ON THE EFFECT OF SUPERVISED PHYSICAL EXERCISE AFTER BARIATRIC SURGERY ON MUSCLE MASS AND BONE DENSITY (OBEFIT STUDY)
- Conditions
- Obesity &Amp;Amp; Overweight, Bariatric Surgery, Physical Exercise
- Trial name
- BARIATRIC (NCT07324447)
- Testing
- physical exercise programme
- Where
- 2 sites in Spain
- Volunteers
- 54 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío