Clinical trials: Obesity Overweight
Obesity
Lipophilic Organic Polluants and Morbid Obesity
1. To study the kinetics of release after bariatric surgery of selected polluants stored in adipose tissue, looking for clinical and/or predictive factors 2.
- Trial name
- POLOB (NCT01969968)
- Testing
- Lipophilic Organic Polluants dosage
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Obesity, Adiposity
HybridAPC for Gastric Mucosal Ablation in Obese Patients.
This study is intended to investigate safety and feasibility of a new weight loss technique called Gastric Mucosal Ablation (GMA) that does not require surgery, but can be achieved using an endoscopic procedure.
- Trial name
- NCT05587491
- Testing
- Hybrid Argonplasma coagulation (HAPC)
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Erbe Elektromedizin GmbH
Obesity, Phentermine Withdrawal
Long-term Phentermine Pharmacotherapy: An Investigation for Symptoms of Dependence, Cravings, or Withdrawal
Phentermine, an amphetamine congener, is the most widely used anti-obesity drug in the U.S. Although phentermine is the agent-of-choice among physicians specializing in obesity treatment, the use of this drug for obesity…
- Trial name
- PC-II (NCT01402674)
- Testing
- Abrupt cessation of phentermine pharmacotherapy
- Where
- 2 sites in United States
- Volunteers
- 269 people
- Sponsor
- Center for Weight Management, California
Obesity, Type 2 Diabetes
A Very High Fiber Diet Versus a Low-carbohydrate Diet for Weight Loss
Using a 2x2 complete factorial design, approximately 140 obese men and women who may or may not have type 2 diabetes will be randomized to one of two conditions (70 in each condition): (a) a high fiber diet, or (b) a…
- Trial name
- NCT01051674
- Testing
- High fiber vs. low-carbohydrate diets
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Loma Linda University
Obesity, Overweight
An Intervention to Improve Nutrition and Physical Activity in Preschoolers in Cuenca, Ecuador
The aim of this study is to design and evaluate an educational and behavioral intervention focused on improving nutrition and physical activity habits among preschoolers in Cuenca, Ecuador, with the overarching goal of preventing…
- Conditions
- Obesity, Overweight, Underweight
- Trial name
- NCT02451410
- Testing
- Nutrition and physical activity
- Where
- 9 sites in Ecuador
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Universidad de Cuenca
Gastro Esophageal Reflux, Obesity (Disorder)
Association Between Obesity and Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is a chronic disorder marked by heartburn and regurgitation, resulting from the reflux of gastric acid or bile into the esophagus.
- Trial name
- NCT07199582
- Volunteers
- 200 people
- Sponsor
- Assiut University
Obesity, Physical Inactivity
"GameDay Ready": Evaluating a Behavioral Weight Management Program for Black Men Living in the Rural South
The primary objective of this study is to test the feasibility and acceptability of a 12-week behavioral weight management intervention adapted for Black men living in the rural South.
- Conditions
- Obesity, Physical Inactivity, Diet, Healthy
- Trial name
- NCT05530980
- Testing
- GameDay Ready Program
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Diabetes Mellitus, Type 2, Obesity
The Dietary Guidelines 3 Diet Patterns Study (DG3D): Phase 2
Based on the findings of our formative work, conduct a one-year intervention among African American Adults using revised culturally tailored materials to examine differences in Healthy Eating Index (HEI) and type 2 diabetes…
- Trial name
- DG3D-Phase2 (NCT05254496)
- Testing
- Dietary Intervention Classes
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Healthy Pregnant Women, Obese Pregnant Women
Pregnancy Cohort Study: Pregnancy as a Window to Future Health
The goal of this observational cohort study is to gain deep insights into how metabolic disorders such as obesity or diabetes during pregnancy affect the metabolic and cardiovascular health of mother and child in the short and…
- Conditions
- Healthy Pregnant Women, Obese Pregnant Women, Gestational Diabetes
- Trial name
- PregWin (NCT06925815)
- Where
- Austria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Neurologic Disorder, Adiposity
Childhood Adiposity and Neurodevelopmental Outcomes Among Offspring of Women With Type 1 Diabetes (CONCEPTT Kids)
This is a follow-up study of children born to mothers who participated in the CONCEPTT Trial. CONCEPTT (a multicentre randomized controlled trial of continuous glucose monitoring (CGM) in women with Type 1 diabetes during…
- Trial name
- NCT04098679
- Where
- 4 sites in Canada
- Volunteers
- 174 people
- Sponsor
- University of Calgary
COPD Exacerbation, Oxygen Toxicity
Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery
The main objective is to evaluate the FreeO2 device combined with noninvasive respiratory support technique for COPD patients and postoperative bariatric surgery patients.
- Conditions
- COPD Exacerbation, Oxygen Toxicity, Abdominal Obesity, Surgery
- Trial name
- NCT04136717
- Testing
- Washout period, NIV - FreeO2, Nasal High flow Oxygen therapy - FreeO2
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- François Lellouche
Obesity, Blood Pressure
Immediate Effects of Whole Body Vibration on Hemodynamic Response and Fatigue in Normotensive People With Obesity
Whole Body Vibration Therapy (WBVT) has been identified as a useful tool to increase peripheral blood flow. The present study aimed at how dynamic exercises with WBVT immediate effect on hemodynamic response and fatigue…
- Conditions
- Obesity, Blood Pressure, Whole Body Vibration, Exercise
- Trial name
- RT (NCT03865368)
- Testing
- Whole Body Vibration Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Okan University
Non-Alcoholic Fatty Liver Disease, Obesity, Morbid
Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
The study is aimed To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Morbid, Brown Fat, Metabolic Disease
- Trial name
- NCT03875625
- Testing
- Bariatric surgery, Dietitian led life style modification intervention, Conventional care (control)
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Obesity
ULTIMATE Study for Weight Loss
The purpose of this study is to help find out more about how the Primary Obesity Surgery Endoluminal (POSE) procedure makes patients feel less hungry and fuller faster, leading to weight loss.
- Trial name
- ULTIMATE (NCT01771276)
- Testing
- g-Cath Suture Anchor Delivery Catheter
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- USGI Medical
Obesity; Drug
Nutritional Therapy to Incretin-based Anti-obesity Medications in the Management of Gastrointestinal Adverse Events
The goal of the study is to evaluate the effect of nutrition intervention on gastrointestinal symptoms, treatment discontinuation rate, nutritional parameters (e.g., dietary intake and eating habits), anthropometric measures…
- Trial name
- NCT06431308
- Testing
- nutritional intervention
- Where
- 3 sites in Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ariel University
Vegetable Acceptance in Early Childhood, Childhood Obesity
Baby's First Bites: Promoting Vegetable Intake in Infants and Toddlers
Overweight and obesity in preschool children is more and more common and predicts overweight in later childhood and adulthood. A healthy eating pattern with many vegetables decreases the risk to develop overweight.
- Conditions
- Vegetable Acceptance in Early Childhood, Childhood Obesity, Childhood Overweight
- Trial name
- NCT03348176
- Testing
- Vegetable exposure, VIPP-Feeding Infants, Control
- Where
- 2 sites in Netherlands
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Obesity
Endoscopic Stomach and Pouch Reduction in Patients With Weight Regain Following Roux-En-Y Bypass Surgery
The Roux-En-Y gastric bypass procedure is the most commonly performed bariatric procedure in the United States. Despite initial weight loss, some patients experience weight regain that may be related to an increase in the size of…
- Trial name
- NCT00411489
- Testing
- endolumenal surgery
- Where
- 4 sites in United States
- Sponsor
- USGI Medical
Obesity, Abdominal, Hypertension
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
The estrogenic deficit characteristic of the climacteric stage is accompanied by a high incidence of health problems, such as the presence of Metabolic Syndrome risk factors that contribute to the increase of cardiovascular…
- Conditions
- Obesity, Abdominal, Hypertension, Quality of Life, Menopause
- Trial name
- NCT05387174
- Testing
- : Nursing intervention in two risk factors of the Metabolic Syndrome, abdominal obesity and arterial hypertension and quality of life in the climacteric period.
- Where
- Ecuador
- Volunteers
- 80 people
- Sponsor
- Universidad de Concepcion
Gestational Diabetes Mellitus
Exercise Intervention to Prevent Gestational Diabetes
This study evaluates the role of exercise intervention in reducing the risk of gestational diabetes mellitus(GDM) risk of overweight/obese(prepregnancy BMI≥24kg/m^2） Chinese pregnant women.
- Trial name
- NCT02304718
- Testing
- Stationary bike
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Healthy
Probiotics to Improve Women's Health
The purpose of the study is explore the effect of probiotics on plasma lipopolysaccharides (LPS) concentrations, as well as insulin and glucose levels, in obese women prior to and after dietary challenges (high carbohydrate meal…
- Trial name
- NCT01800760
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
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