Clinical trials: Obesity Overweight
Obesity, Type 2 Diabetes
Effects of Oral Sodium Butyrate Supplementation on Body Weight Reduction in Overweight/Obese Individuals With and Without Type 2 Diabetes
The goal of this clinical trial (randomized controlled trial with parallel group design) is to evaluate the effects of oral sodium butyrate supplementation for 12 weeks, compared with placebo, in addition to a moderately…
- Trial name
- ButRed (NCT07252609)
- Testing
- Sodium Butyrate (NaBut)
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Federico II University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis
A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)
This study is researching an experimental drug called ALN-CIDEB, also referred to as "study drug". The study is focused on participants with metabolic dysfunction-associated steatotic liver disease (MASLD) (Part A) and metabolic…
- Trial name
- NCT06836609
- Testing
- ALN-CIDEB
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 132 people
- Sponsor
- Regeneron Pharmaceuticals
Overweight and Obesity, Eating Disorders
Project Health: Enhancing Effectiveness of an Obesity Prevention Program
This 2-site effectiveness trial will test whether a brief dissonance-based obesity prevention program delivered in single sex groups combined with food response and attention training will produce significantly larger weight gain…
- Trial name
- NCT06067763
- Testing
- Project Health, Response and Attention Training, The Weight of the Nation
- Where
- 2 sites in United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Cardiovascular Diseases, Diabetes
Białystok PLUS - Polish Longitudinal University Study
The main goal of the study is to provide a unique multidimensional picture of the health of the population with simultaneous optimal standards of sampling, processing and storing of data and biomaterial that will allow…
- Conditions
- Cardiovascular Diseases, Diabetes, Neuro-Degenerative Disease, Obesity
- Trial name
- Bialystok+ (NCT03197363)
- Testing
- Discovering novel risk factors.
- Where
- Poland
- Volunteers
- 8,320 people
- Sponsor
- Medical University of Bialystok
Healthy Human Male Subjects
The Influence of Liraglutide on the Reward Properties of Food: an fMRI Study on Healthy Volunteers
Clinical experience has confirmed the anorexic effect of Glucagon-like-peptide 1 (GLP-1) mimetics in comparison to DPP-4 inhibitors.
- Trial name
- NCT01695109
- Testing
- Liraglutide
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Obesity, Physical Fitness
Comprehensive Versus Traditional Lifestyle Program
Despite recommends that school-based interventions use a comprehensive approach for health promotions; most fitness programs exclusively emphasize physical activity.
- Conditions
- Obesity, Physical Fitness, Cognitive Function 1, Social
- Trial name
- NCT03182621
- Testing
- THINK, SPARK
- Volunteers
- 105 people
- Sponsor
- University of Miami
Obesity
Piloting Visual Chat in Internet Obesity Treatment
CHAT is an internet-based weight loss research program designed for women with overweight or obesity who want to lose weight through dietary change and increased physical activity.
- Trial name
- CHAT (NCT03491293)
- Testing
- Behavioral Weight Loss + Text, Behavioral Weight Loss + Video
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Obesity, Pregnancy
A Clinical Care Pathway for Obese Pregnant Women: A Pilot Cluster RCT
Clinics will be randomized to the use of the care pathway for obese pregnant women or standard care. Women who are (1) up to 20 weeks + 6 days gestation into their pregnancy, (2) are carrying one baby (not twins) that is healthy…
- Trial name
- NCT02534051
- Testing
- Clinical Care Pathway
- Where
- Canada
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- McMaster University
Obesity, Physical Activity
PRESENCE 2: Predicting Sedentary Entertainment Choices and Effects
The purpose of this study is to determine whether playing motion-controlled video games produces low caloric intake and higher caloric expenditure than watching TV or playing traditional video games.
- Trial name
- NCT01523795
- Testing
- Motion-controlled video gaming, Traditional video gaming, Television watching
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
NAFLD, Obesity
Vigabatrin and Insulin Sensitivity
Nonalcoholic fatty liver disease (NAFLD) is a common complication of obesity and is associated with an increased risk of developing type 2 diabetes.
- Trial name
- NCT04321395
- Testing
- Vigabatrin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Obesity, Insulin Resistance
Vitamin K and Glucose Metabolism in Adults at Risk for Diabetes (Vita-K 'n' Adults Study)
Given that glutamate carboxylation or decarboxylation is key to the metabolic role of osteocalcin (at least in mouse models) and that carboxylation is vitamin K dependent, it is critical to isolate the effect of vitamin K…
- Conditions
- Obesity, Insulin Resistance, Insulin Sensitivity, Beta-Cell Dysfunction
- Trial name
- NCT02366481
- Testing
- Low-Dose Vitamin K2 Supplement (menaquinone-7; 90-mcg/d), High-Dose Vitamin K2 Supplement (menaquinone-7; 180-mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Obesity, Vitamin D Deficiency
Impact of Maternal Body Weight on Vitamin D Status During Pregnancy
Research shows high levels of vitamin D deficiency in pregnant women in Northern Ireland. Body composition is a determinant of vitamin D status.
- Trial name
- MO-VITD (NCT02713009)
- Testing
- Pregnancy multi-vitamin (including 10μg vitamin D3), 10μg vitamin D3
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Obesity
Effect of an Antiinflammatory Diet on Postprandial Gene Expression of Mononuclear Cells of Adult Obese Women
Obesity is one of the major health problems worldwide. The consumption of healthy-dietary patterns can be difficult in some countries due to the availability of certain foods. Suggestion of alternative foods could be a necessity.
- Trial name
- NCT04920409
- Testing
- FAWGT diet, Usual diet (UD)
- Where
- Colombia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad de Caldas
Obesity, Vitamin D3 Deficiency
Vitamins D and K Effects on Vascular Function in Obese Adults.
A prospective, randomized, placebo-controlled, double-blind study that aims to evaluate the effects of combined vitamin D3 and K2-MK7 supplementation on vascular function, sympathetic tone, metabolic biomarkers and inflammatory…
- Trial name
- NCT05689632
- Testing
- Vitamin D3 + K2-MK7, Vitamin D3
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Pedro Ernesto
Cardiovascular Diseases, Coronary Disease
Coronary Artery Risk Development in Young Adults
To measure changes in coronary heart disease risk factors in cohorts of Black and White males and females 18 to 30 years of age at baseline.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Hypertension, Heart Diseases
- Trial name
- CARDIA (NCT00005130)
- Volunteers
- 5,115 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hyperlipidemia, Diabetes Mellitus
Baseline Physiology Studies in Carriers of Gene Variant X Conferring Major Risk of CVD-prone Metabolic Disorders
The purpose of the present study is to conduct a thorough and relevant physiology study of carriers and non-carriers of the gene variant X in order to determine the effect of the genetic variant on various metabolic parameters.
- Conditions
- Hyperlipidemia, Diabetes Mellitus, Metabolic Syndrome, Arterial Hypertension
- Trial name
- NCT01571609
- Testing
- first phase insulin secretion (FPIR), Hyperinsulinemic euglycemic clamp (HEC), glucose tracer, and palmitate tracer
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Lifestyle-related Condition
Obesity Pathway Intervention Among Overweight and Obese Adults at Primary Care Centers in Hail, Saudi Arabia
The goal of this pragmatic trial is to test the benefit of using dietary advice and health coaching for physical activities for obese and overweight in lowering body weight and making them lead a healthy lifestyle.
- Trial name
- Telehealth (NCT05654337)
- Testing
- Expert health counseling
- Where
- Saudi Arabia
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The New Model of Care, Hail Health Cluster
Food Labelling, Eating Behaviour
Food Menu Labelling Effects on Individuals With Eating Disorders and Other Mental Health Conditions.
Calorie labelling in out-of-home (OOH) settings was introduced by the government in England as part of a wider strategy to 'tackle obesity' (DHSC, 2020).
- Conditions
- Food Labelling, Eating Behaviour, Mental Health, Eating Disorder
- Trial name
- NCT07809295
- Testing
- Control condition, Calorie labelling, Nutri-Score labelling
- Where
- United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Uric Acid
Orlistat Reduces Uric Acid in Overweight/Obese Patients With Hyperuricemia
To clarify the uric acid-lowering efficacy of orlistat in overweight/obese patients with hyperuricemia, and to evaluate the safety of orlistat treatment
- Trial name
- NCT05496075
- Testing
- Orlistat
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Obesity, Morbid
Outpatient Bariatric Surgery
This study first presents the organizational path and the health interventions included in the care episode for outpatient bariatric surgery, as compared to the health interventions usually performed in the care episode for…
- Trial name
- Bariatric Ambu (NCT04423575)
- Testing
- Outpatient health care pathway
- Where
- France
- Volunteers
- 60 people
- Sponsor
- IHU Strasbourg
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.