Clinical trials: Obesity Overweight
Obesity, Weight Loss
Feasibility Trial of a Problem-Solving Weight Loss Mobile Application
The purpose of this research was to develop and test the feasibility of Habit, a weight loss mobile application that was designed to coach patients through their weight loss challenges.
- Trial name
- NCT02192905
- Testing
- Diabetes Prevention Program Lifestyle Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Polycystic Ovarian Syndrome, Infertility
Healthy Eating for Reproductive Health (HERHealth)
This study will be a 6-month intervention that is examining how different dietary approached may be useful for women with Polycystic Ovarian Syndrome (PCOS) who are attempting pregnancy, particularly by measuring changes in…
- Conditions
- Polycystic Ovarian Syndrome, Infertility, Obesity, Overweight
- Trial name
- HERHealth (NCT01509066)
- Testing
- Diet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Dyslipidemia, Obesity &Amp; Overweight
Improvement and Safety of Nutrilite Protein MetX Pro on Weight Management in Overweight Individuals With Dyslipidemia
The goal of this randomized, double-blind, placebo-controlled, single center study is to evaluate the impact of Nutrilite Protein MetX Pro (the study product, a high-protein compound beverages supplemented with multiple plant…
- Trial name
- NCT07094022
- Testing
- Nutrilite Protein MetX Pro
- Where
- 2 sites in China
- Volunteers
- 66 people
- Sponsor
- Amway (China) R&D Center
Prader-Willi Syndrome, Obesity
Plasma Adiponectin Level and Vascular Endothelial and Smooth Muscle Cell Function in Children With Prader-Willi Syndrome
Context: Prader-Willi syndrome (PWS) is a genetic disorder characterized by childhood-onset obesity and endocrine dysfunction that leads to cardiovascular disability and early death within the first 3 decades of life.
- Trial name
- NCT01479322
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Obesity
To Evaluate the Safety, Tolerability, PK, PK-PD Relation of KD101 in the Fed State in Obese or Overweight Subjects
To Evaluate the safety, tolerability and pharmacokinetic property after KD101 multiple oral dosing in the fed state in obese or overweight subjects.
- Trial name
- NCT02462031
- Testing
- KD101
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kwang Dong Pharmaceutical co., ltd.
Metabolic Syndrome, Metabolic Syndrome Obesity
Impact of Medical Nutrition Therapy and Follow-Up Frequency on Metabolic Syndrome Parameters
There is no study that has investigated the effects of medical nutrition therapy and more frequent follow-up via telehealth on metabolic syndrome parameters in patients with MetS who have multiple metabolic disorders such as…
- Conditions
- Metabolic Syndrome, Metabolic Syndrome Obesity, Metabolic Syndrome Parameters
- Trial name
- NCT06813131
- Testing
- Dietary counseling, calling via telephone
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Hacettepe University
Morbid Obesity, Bariatric Surgery Candidate
Transversus Abdominis Plane (TAP) Block Using Liposomal Bupivacaine in Metabolic and Bariatric Surgery Patients
To investigate if laparoscopic Transversus Abdominis Plane (TAP) block using plain bupivacaine is equivalent to using liposomal bupivacaine in patients undergoing metabolic and bariatric surgery.
- Trial name
- TAP (NCT05537883)
- Testing
- Liposomal bupivacaine, Bupivacaine Injection
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Wake Forest University Health Sciences
Obesity
A Study to Measure Energy Expenditure and Food Intake in Participants With Obesity Using Tirzepatide
This is a study of tirzepatide in participants with obesity. The main purpose is to learn more about how tirzepatide affects the number of calories participants burn and the amount of food they eat.
- Trial name
- NCT04081337
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Eli Lilly and Company
Obesity/Therapy
Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity
Glucagon-like peptide 1 receptor agonists (GLP-1RA), such as Ozempic and Wegovy, have been rapidly adopted for the treatment of obesity in both youth and adults.
- Trial name
- PLASTIC (NCT07021937)
- Testing
- Semaglutide 1.7mg subcutaneous
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Obesity, Weight Loss
Weight Loss Via Bariatric Surgery and Lifestyle Modification
Gastric myoelectric, inflammatory, and hormonal responses, body compositional, energy expenditure, and metabolic changes during the development of obesity and the weight loss process are underinvestigated.
- Trial name
- NCT05775172
- Testing
- Sleeve gastrectomy, Lifestyle intervention, Control
- Where
- Saudi Arabia
- Volunteers
- 79 people
- Sponsor
- King Saud University
Congestive Heart Failure
Assess Measurements of Wireless Cardiac Output Device
Heart failure is a common cardiovascular problem which is increasing in both prevalence and incidence and associated with substantial morbidity and mortality.
- Trial name
- Remote-CO-1 (NCT02252757)
- Testing
- CoVa
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Aventyn, Inc.
Obesity
Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity
The purpose of this study is to understand the specific outflow and difference between normal weight and volunteers with obesity of upper body subcutaneous adipose tissue in response to a mixed meal challenge by site specific…
- Trial name
- NCT07031297
- Testing
- Meal Study
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight and Obesity
Low-frequency High-Intensity Interval Training in Overweight or Obese Young Adults
Background: The relationship between the frequency of high-intensity interval training (HIIT) and the resultant adaptations is largely unclear.
- Trial name
- NCT03904810
- Testing
- Exercise intervention
- Where
- Hong Kong
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Obesity, Type 2 Diabetes
Improving Diabetes Through Lifestyle and Surgery
Weight loss is effective in reducing many complications of obesity, with the majority of patients who undergo bariatric surgery having substantial improvements in their weight-related illnesses.
- Trial name
- IDeaLS (NCT01667783)
- Testing
- Gastric Banding, Medical Weight Loss, Gastric Bypass
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Obesity, Cardiovascular Risk Factors
Effects of Soy Based Dietary Supplements on Cardiometabolic Risk Factors.
This study will test the effect of both Luna Rich X© and Reliv Now© against placebo pills or powder (control) on blood lipids. It will also explore the potential effects of these dietary supplements on inflammation markers and…
- Trial name
- NCT02490683
- Testing
- Luna Rich X, Reliv Now
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loma Linda University
Overweight, Obesity
Simplifying Diet Tracking in a Digital Weight Loss Intervention
The purpose of this study is to compare two approaches for tracking dietary intake in a 12-month fully digital weight loss intervention: (1) Simplified approach: track Red Zone Foods (e.g., foods high in calories and low in…
- Conditions
- Overweight, Obesity, Weight Loss, Health Behavior
- Trial name
- NCT07601061
- Testing
- Simplified Dietary Self-Monitoring, Detailed Dietary Self-Monitoring, Core Behavioral Weight Loss Intervention
- Where
- United States
- Volunteers
- 328 people
- Sponsor
- Stanford University
Low Back Pain in Obese Patients After Important Weight Loss
Prospective Study on the Consequences of Weight Loss After Bariatric Surgery on Obese Patients' Spine.
The purpose of this study is to determine how an important weight loss after bariatric surgery affects obese patients ' spine, and the effects it has on low back pain, sagittal alignment and lipomatosis .
- Trial name
- SPINOB (NCT04893954)
- Testing
- Full Spine Radiography, Lumbar spine MRI
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Health Status Disparities, Pediatric Obesity
Determining the Optimal Amount of Structured Environments for Healthy Kids
Studies show that virtually all increases in children's (5-12yrs) BMI occur during the summer, no matter children's' weight status (i.e., normal weight, overweight, or obese) at summer entry.
- Conditions
- Health Status Disparities, Pediatric Obesity, Ethnic Groups, Socioeconomic Factors
- Trial name
- DOSE (NCT06158594)
- Testing
- Summer day camp
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Pediatric Obesity
The Peds Obesity Study
The aim of the study is to investigate, in severely obese adolescents, the effects of a high protein, restricted carbohydrates utilizing partial meal replacements diet (HPRC-PMR) on weight loss, body composition, and bio-chemical…
- Trial name
- NCT02353637
- Testing
- Partial Meal Replacements
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Obese
Influence of Changes in Food Group Variety on Food Cravings, Energy Intake, and Weight Loss After Bariatric Surgery
The purpose of this study is to find out if there is any change in diet on food cravings and weight loss in the 12 months following bariatric surgery.
- Trial name
- NCT01399177
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
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